P31431: Syndecan-4

General Information

Protein names	- Syndecan-4 - SYND4 - Amphiglycan - Ryudocan core protein
Gene names	SDC4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P31431

5 N-termini

4 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAPARLFALL LFFVGGVAES IRETEVIDPQ DLLEGRYFSG ALPDDEDVVG PGQESDDFEL
        70         80         90        100        110        120
SGSGDLDDLE DSMIGPEVVH PLVPLDNHIP ERAGSGSQVP TEPKKLEENE VIPKRISPVE
       130        140        150        160        170        180
ESEDVSNKVS MSSTVQGSNI FERTEVLAAL IVGGIVGILF AVFLILLLMY RMKKKDEGSY
       190
DLGKKPIYKK APTNEFYA

Isoforms

- Isoform 2 of Syndecan-4

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P31431-1-unknown	MAPARL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89134
P31431-19-unknown	ESIRET...	19	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P31431-19-unknown	ESIRET...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112120
P31431-71-unknown	DSMIGP...	71	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19034
P31431-71-unknown	DSMIGP...	71	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17570
P31431-71-unknown	DSMIGP...	71	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140714
P31431-115-unknown	RISPVE...	115	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31778
P31431-115-unknown	RISPVE...	115	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27577
P31431-115-unknown	RISPVE...	115	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143219
P31431-129-unknown	VSMSST...	129	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27579

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LDDLED	70	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19034
...LDDLED	70	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17570
...LDDLED	70	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123849
...EVIPKR	114	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31778
...EVIPKR	114	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27577
...EVIPKR	114	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126445
...DVSNKV	128	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27579
...DVSNKV	128	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127108
...NEFYA	198	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	70	DLED.\|.DSMI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	70	DLED.\|.DSMI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
THRB_HUMAN	114	IPKR.\|.RISP	inferred from experiment	unknown	MEROPS	Buddecke E	Schmidt A et al.:Plasmin- and thrombin-accelerat... (S01.233)	16087677,
PLMN_HUMAN	114	IPKR.\|.RISP	inferred from experiment	unknown	MEROPS	Buddecke E	Schmidt A et al.:Plasmin- and thrombin-accelerat... (S01.233)	16087677,
PLMN_HUMAN	128	SNKV.\|.VSMS	inferred from experiment	unknown	MEROPS	Buddecke E	Schmidt A et al.:Plasmin- and thrombin-accelerat... (S01.233)	16087677,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)