P41271: Neuroblastoma suppressor of tumorigenicity 1

General Information

Protein names	- Neuroblastoma suppressor of tumorigenicity 1 - DAN domain family member 1 - Protein N03 - Zinc finger protein DAN
Gene names	NBL1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P41271

3 N-termini

8 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MMLRVLVGAV LPAMLLAAPP PINKLALFPD KSAWCEAKNI TQIVGHSGCE AKSIQNRACL
        70         80         90        100        110        120
GQCFSYSVPN TFPQSTESLV HCDSCMPAQS MWEIVTLECP GHEEVPRVDK LVEKILHCSC
       130        140        150        160        170        180
QACGKEPSHE GLSVYVQGED GPGSQPGTHP HPHPHPHPGG QTPEPEDPPG APHTEEEGAE

D

Isoforms

- Isoform 2 of Neuroblastoma suppressor of tumorigenicity 1

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 8 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P41271-2-unknown	MLRVLV...	2	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000394079
P41271-2-unknown	MLRVLV...	2	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000449007
P41271-2-unknown	MLRVLV...	2	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt194414
P41271-17-unknown	AAPPPI...	17	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P41271-17-unknown	AAPPPI...	17	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111915
P41271-75-unknown	STESLV...	75	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17643
P41271-75-unknown	STESLV...	75	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142971

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NTFPQS	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17643
...NTFPQS	74	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126179
...SMWEIV	94	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000391858
...SMWEIV	94	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154306
...VPRVDK	109	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399333
...VPRVDK	109	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154471
...VEKILH	116	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000400250
...VEKILH	116	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154550
...EKILHC	117	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000412419
...EKILHC	117	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154554
...GKEPSH	128	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000390607
...GKEPSH	128	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154708
...GQTPEP	164	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000394079
...GQTPEP	164	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155170
...EGAED	181	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EGAED	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77966

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	74	FPQS.\|.STES	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)