P15880: 40S ribosomal protein S2

General Information

Protein names	- 40S ribosomal protein S2 - 40S ribosomal protein S4 - Protein LLRep3 - Small ribosomal subunit protein uS5 {ECO:0000303\|PubMed:24524803}
Gene names	RPS2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P15880

15 N-termini

11 C-termini

10 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADDAGAAGG PGGPGGPGMG NRGGFRGGFG SGIRGRGRGR GRGRGRGRGA RGGKAEDKEW
        70         80         90        100        110        120
MPVTKLGRLV KDMKIKSLEE IYLFSLPIKE SEIIDFFLGA SLKDEVLKIM PVQKQTRAGQ
       130        140        150        160        170        180
RTRFKAFVAI GDYNGHVGLG VKCSKEVATA IRGAIILAKL SIVPVRRGYW GNKIGKPHTV
       190        200        210        220        230        240
PCKVTGRCGS VLVRLIPAPR GTGIVSAPVP KKLLMMAGID DCYTSARGCT ATLGNFAKAT
       250        260        270        280        290
FDAISKTYSY LTPDLWKETV FTKSPYQEFT DHLVKTHTRV SVQRTQAPAV ATT

Isoforms

Sequence View

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P15880-2-unknown	MADDAG...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P15880-2-Acetylation	ADDAGA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P15880-2-Acetylation	ADDAGA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P15880-2-Acetylation	ADDAGA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P15880-61-unknown	MPVTKL...	61		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000454837
P15880-63-unknown	VTKLGR...	63		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000436227
P15880-90-unknown	ESEIID...	90		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000460860
P15880-99-unknown	GASLKD...	99		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5618
P15880-100-unknown	ASLKDE...	100		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3655
P15880-100-unknown	ASLKDE...	100		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7343
P15880-100-unknown	ASLKDE...	100		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5619
P15880-126-	AFVAIG...	126			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P15880-201-	GTGIVS...	201			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P15880-215-unknown	MMAGID...	215		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13978
P15880-216-unknown	MAGIDD...	216		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13979
P15880-232-unknown	TLGNFA...	232		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3656
P15880-264-	SPYQEF...	264			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P15880-266-unknown	YQEFTD...	266		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11232
P15880-268-unknown	EFTDHL...	268		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18781
P15880-268-unknown	EFTDHL...	268		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17386

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...IDFFLG	98	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5618
...DFFLGA	99	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3655
...DFFLGA	99	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7343
...DFFLGA	99	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5619
...ASLKDE	104	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000454837
...PKKLLM	214	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13978
...KKLLMM	215	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13979
...LMMAGI	218	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000433034
...RGCTAT	231	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3656
...FTKSPY	265	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11232
...KSPYQE	267	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18781
...KSPYQE	267	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17386
...AVATT	293		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...AVATT	293		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...AVATT	293	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...AVATT	293		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...AVATT	293		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	98	FFLG.\|.GASL	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	99	FLGA.\|.ASLK	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	99	FLGA.\|.ASLK	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	99	FLGA.\|.ASLK	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAM_HUMAN	214	KLLM.\|.MMAG	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	215	LLMM.\|.MAGI	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CATB_HUMAN	231	CTAT.\|.TLGN	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	265	KSPY.\|.YQEF	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
MEP1B_HUMAN	267	PYQE.\|.EFTD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	267	PYQE.\|.EFTD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

TopFIND

P15880: 40S ribosomal protein S2

General Information

15

N-termini

11

C-termini

10

Cleavages

0

Substrates

Sequence

Isoforms

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Protein Neighborhood

Domains & Features

15 N-termini - 11 C-termini - 10 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates