Q9BXP5: Serrate RNA effector molecule homolog

General Information

Protein names	- Serrate RNA effector molecule homolog - Arsenite-resistance protein 2
Gene names	SRRT
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BXP5

9 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Serrate RNA effector molecule homolog - Isoform 3 of Serrate RNA effector molecule homolog - Isoform 4 of Serrate RNA effector molecule homolog - Isoform 5 of Serrate RNA effector molecule homolog

Sequence View

        10         20         30         40         50         60
MGDSDDEYDR RRRDKFRRER SDYDRSRERD ERRRGDDWND REWDRGRERR SRGEYRDYDR
        70         80         90        100        110        120
NRRERFSPPR HELSPPQKRM RRDWDEHSSD PYHSGYEMPY AGGGGGPTYG PPQPWGHPDV
       130        140        150        160        170        180
HIMQHHVLPI QARLGSIAEI DLGVPPPVMK TFKEFLLSLD DSVDETEAVK RYNDYKLDFR
       190        200        210        220        230        240
RQQMQDFFLA HKDEEWFRSK YHPDEVGKRR QEARGALQNR LRVFLSLMET GWFDNLLLDI
       250        260        270        280        290        300
DKADAIVKML DAAVIKMEGG TENDLRILEQ EEEEEQAGKP GEPSKKEEGR AGAGLGDGER
       310        320        330        340        350        360
KTNDKDEKKE DGKQAENDSS NDDKTKKSEG DGDKEEKKED SEKEAKKSSK KRNRKHSGDD
       370        380        390        400        410        420
SFDEGSVSES ESESESGQAE EEKEEAEEAL KEKEKPKEEE WEKPKDAAGL ECKPRPLHKT
       430        440        450        460        470        480
CSLFMRNIAP NISRAEIISL CKRYPGFMRV ALSEPQPERR FFRRGWVTFD RSVNIKEICW
       490        500        510        520        530        540
NLQNIRLREC ELSPGVNRDL TRRVRNINGI TQHKQIVRND IKLAAKLIHT LDDRTQLWAS
       550        560        570        580        590        600
EPGTPPLPTS LPSQNPILKN ITDYLIEEVS AEEEELLGSS GGAPPEEPPK EGNPAEINVE
       610        620        630        640        650        660
RDEKLIKVLD KLLLYLRIVH SLDYYNTCEY PNEDEMPNRC GIIHVRGPMP PNRISHGEVL
       670        680        690        700        710        720
EWQKTFEEKL TPLLSVRESL SEEEAQKMGR KDPEQEVEKF VTSNTQELGK DKWLCPLSGK
       730        740        750        760        770        780
KFKGPEFVRK HIFNKHAEKI EEVKKEVAFF NNFLTDAKRP ALPEIKPAQP PGPAQILPPG
       790        800        810        820        830        840
LTPGLPYPHQ TPQGLMPYGQ PRPPILGYGA GAVRPAVPTG GPPYPHAPYG AGRGNYDAFR
       850        860        870
GQGGYPGKPR NRMVRGDPRA IVEYRDLDAP DDVDFF         10         20         30         40         50         60
MGDSDDEYDR RRRDKFRRER SDYDRSRERD ERRRGDDWND REWDRGRERR SRGEYRDYDR
        70         80         90        100        110        120
NRRERFSPPR HELSPPQKRM RRDWDEHSSD PYHSGYEMPY AGGGGGPTYG PPQPWGHPDV
       130        140        150        160        170        180
HIMQHHVLPI QARLGSIAEI DLGVPPPVMK TFKEFLLSLD DSVDETEAVK RYNDYKLDFR
       190        200        210        220        230        240
RQQMQDFFLA HKDEEWFRSK YHPDEVGKRR QEARGALQNR LRVFLSLMET GWFDNLLLDI
       250        260        270        280        290        300
DKADAIVKML DAAVIKMEGG TENDLRILEQ EEEEEQAGKP GEPSKKEEGR AGAGLGDGER
       310        320        330        340        350        360
KTNDKDEKKE DGKQAENDSS NDDKTKKSEG DGDKEEKKED SEKEAKKSSK KRNRKHSGDD
       370        380        390        400        410        420
SFDEGSVSES ESESESGQAE EEKEEAEEAL KEKEKPKEEE WEKPKDAAGL ECKPRPLHKT
       430        440        450        460        470        480
CSLFMRNIAP NISRAEIISL CKRYPGFMRV ALSEPQPERR FFRRGWVTFD RSVNIKEICW
       490        500        510        520        530        540
NLQNIRLREC ELSPGVNRDL TRRVRNINGI TQHKQIVRND IKLAAKLIHT LDDRTQLWAS
       550        560        570        580        590        600
EPGTPPLPTS LPSQNPILKN ITDYLIEEVS AEEEELLGSS GGAPPEEPPK EGNPAEINVE
       610        620        630        640        650        660
RDEKLIKVLD KLLLYLRIVH SLDYYNTCEY PNEDEMPNRC GIIHVRGPMP PNRISHGEVL
       670        680        690        700        710        720
EWQKTFEEKL TPLLSVRESL SEEEAQKMGR KDPEQEVEKF VTSNTQELGK DKWLCPLSGK
       730        740        750        760        770        780
KFKGPEFVRK HIFNKHAEKI EEVKKEVAFF NNFLTDAKRP ALPEIKPAQP PGPAQILPPG
       790        800        810        820        830        840
LTPGLPYPHQ TPQGLMPYGQ PRPPILGYGA GAVRPAVPTG GPPYPHAPYG AGRGNYDAFR
       850        860        870
GQGGYPGKPR NRMVRGDPRA IVEYRDLDAP DDVDFF         10         20         30         40         50         60
MGDSDDEYDR RRRDKFRRER SDYDRSRERD ERRRGDDWND REWDRGRERR SRGEYRDYDR
        70         80         90        100        110        120
NRRERFSPPR HELSPPQKRM RRDWDEHSSD PYHSGYEMPY AGGGGGPTYG PPQPWGHPDV
       130        140        150        160        170        180
HIMQHHVLPI QARLGSIAEI DLGVPPPVMK TFKEFLLSLD DSVDETEAVK RYNDYKLDFR
       190        200        210        220        230        240
RQQMQDFFLA HKDEEWFRSK YHPDEVGKRR QEARGALQNR LRVFLSLMET GWFDNLLLDI
       250        260        270        280        290        300
DKADAIVKML DAAVIKMEGG TENDLRILEQ EEEEEQAGKP GEPSKKEEGR AGAGLGDGER
       310        320        330        340        350        360
KTNDKDEKKE DGKQAENDSS NDDKTKKSEG DGDKEEKKED SEKEAKKSSK KRNRKHSGDD
       370        380        390        400        410        420
SFDEGSVSES ESESESGQAE EEKEEAEEAL KEKEKPKEEE WEKPKDAAGL ECKPRPLHKT
       430        440        450        460        470        480
CSLFMRNIAP NISRAEIISL CKRYPGFMRV ALSEPQPERR FFRRGWVTFD RSVNIKEICW
       490        500        510        520        530        540
NLQNIRLREC ELSPGVNRDL TRRVRNINGI TQHKQIVRND IKLAAKLIHT LDDRTQLWAS
       550        560        570        580        590        600
EPGTPPLPTS LPSQNPILKN ITDYLIEEVS AEEEELLGSS GGAPPEEPPK EGNPAEINVE
       610        620        630        640        650        660
RDEKLIKVLD KLLLYLRIVH SLDYYNTCEY PNEDEMPNRC GIIHVRGPMP PNRISHGEVL
       670        680        690        700        710        720
EWQKTFEEKL TPLLSVRESL SEEEAQKMGR KDPEQEVEKF VTSNTQELGK DKWLCPLSGK
       730        740        750        760        770        780
KFKGPEFVRK HIFNKHAEKI EEVKKEVAFF NNFLTDAKRP ALPEIKPAQP PGPAQILPPG
       790        800        810        820        830        840
LTPGLPYPHQ TPQGLMPYGQ PRPPILGYGA GAVRPAVPTG GPPYPHAPYG AGRGNYDAFR
       850        860        870
GQGGYPGKPR NRMVRGDPRA IVEYRDLDAP DDVDFF         10         20         30         40         50         60
MGDSDDEYDR RRRDKFRRER SDYDRSRERD ERRRGDDWND REWDRGRERR SRGEYRDYDR
        70         80         90        100        110        120
NRRERFSPPR HELSPPQKRM RRDWDEHSSD PYHSGYEMPY AGGGGGPTYG PPQPWGHPDV
       130        140        150        160        170        180
HIMQHHVLPI QARLGSIAEI DLGVPPPVMK TFKEFLLSLD DSVDETEAVK RYNDYKLDFR
       190        200        210        220        230        240
RQQMQDFFLA HKDEEWFRSK YHPDEVGKRR QEARGALQNR LRVFLSLMET GWFDNLLLDI
       250        260        270        280        290        300
DKADAIVKML DAAVIKMEGG TENDLRILEQ EEEEEQAGKP GEPSKKEEGR AGAGLGDGER
       310        320        330        340        350        360
KTNDKDEKKE DGKQAENDSS NDDKTKKSEG DGDKEEKKED SEKEAKKSSK KRNRKHSGDD
       370        380        390        400        410        420
SFDEGSVSES ESESESGQAE EEKEEAEEAL KEKEKPKEEE WEKPKDAAGL ECKPRPLHKT
       430        440        450        460        470        480
CSLFMRNIAP NISRAEIISL CKRYPGFMRV ALSEPQPERR FFRRGWVTFD RSVNIKEICW
       490        500        510        520        530        540
NLQNIRLREC ELSPGVNRDL TRRVRNINGI TQHKQIVRND IKLAAKLIHT LDDRTQLWAS
       550        560        570        580        590        600
EPGTPPLPTS LPSQNPILKN ITDYLIEEVS AEEEELLGSS GGAPPEEPPK EGNPAEINVE
       610        620        630        640        650        660
RDEKLIKVLD KLLLYLRIVH SLDYYNTCEY PNEDEMPNRC GIIHVRGPMP PNRISHGEVL
       670        680        690        700        710        720
EWQKTFEEKL TPLLSVRESL SEEEAQKMGR KDPEQEVEKF VTSNTQELGK DKWLCPLSGK
       730        740        750        760        770        780
KFKGPEFVRK HIFNKHAEKI EEVKKEVAFF NNFLTDAKRP ALPEIKPAQP PGPAQILPPG
       790        800        810        820        830        840
LTPGLPYPHQ TPQGLMPYGQ PRPPILGYGA GAVRPAVPTG GPPYPHAPYG AGRGNYDAFR
       850        860        870
GQGGYPGKPR NRMVRGDPRA IVEYRDLDAP DDVDFF

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

9 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9BXP5-1-unknown	MGDSDD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90712
Q9BXP5-1-unknown	MGDSDD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90713
Q9BXP5-1-unknown	MGDSDD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90714
Q9BXP5-1-unknown	MGDSDD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90715
Q9BXP5-2-unknown	MGDSDD...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BXP5-2-Acetylation	GDSDDE...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BXP5-2-Acetylation	GDSDDE...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111675
Q9BXP5-2-Acetylation	GDSDDE...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111676
Q9BXP5-2-Acetylation	GDSDDE...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111677
Q9BXP5-2-Acetylation	GDSDDE...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111678
Q9BXP5-162-unknown	SVDETE...	162		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171697
Q9BXP5-162-unknown	SVDETE...	162		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171698
Q9BXP5-162-unknown	SVDETE...	162		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171699
Q9BXP5-162-unknown	SVDETE...	162		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171700
Q9BXP5-162-	SVDETE...	162			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9BXP5-579-unknown	SSGGAP...	579		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174067
Q9BXP5-579-unknown	SSGGAP...	579		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174068
Q9BXP5-579-unknown	SSGGAP...	579		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174069
Q9BXP5-579-unknown	SSGGAP...	579		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174070
Q9BXP5-579-	SSGGAP...	579			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9BXP5-579-	SSGGAP...	579			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9BXP5-579-	SSGGAP...	579			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9BXP5-703-unknown	SNTQEL...	703		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6747
Q9BXP5-703-unknown	SNTQEL...	703		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155480
Q9BXP5-703-unknown	SNTQEL...	703		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155875
Q9BXP5-703-unknown	SNTQEL...	703		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155876
Q9BXP5-703-unknown	SNTQEL...	703		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155884
Q9BXP5-841-unknown	GQGGYP...	841		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18117
Q9BXP5-841-unknown	GQGGYP...	841		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156503
Q9BXP5-841-unknown	GQGGYP...	841		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156636
Q9BXP5-841-unknown	GQGGYP...	841		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156639
Q9BXP5-841-unknown	GQGGYP...	841		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156649

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...EKFVTS	702	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6747
...EKFVTS	702	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt138917
...EKFVTS	702	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt139329
...EKFVTS	702	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt139330
...EKFVTS	702	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt139340
...YDAFRG	840	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18117
...YDAFRG	840	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt139987
...YDAFRG	840	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt140121
...YDAFRG	840	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt140124
...YDAFRG	840	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt140134
...DVDFF	876	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...DVDFF	876	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt86333
...DVDFF	876	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt86332
...DVDFF	876	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt86330
...DVDFF	876	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt86331
...DVDFF	876		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...DVDFF	876		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...DVDFF	876		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...DVDFF	876		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	702	FVTS.\|.SNTQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	840	AFRG.\|.GQGG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)