Q9Y277: Voltage-dependent anion-selective channel protein 3

General Information

Protein names	- Voltage-dependent anion-selective channel protein 3 - VDAC-3 - hVDAC3 - Outer mitochondrial membrane protein porin 3
Gene names	VDAC3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y277

4 N-termini

2 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MCNTPTYCDL GKAAKDVFNK GYGFGMVKID LKTKSCSGVE FSTSGHAYTD TGKASGNLET
        70         80         90        100        110        120
KYKVCNYGLT FTQKWNTDNT LGTEISWENK LAEGLKLTLD TIFVPNTGKK SGKLKASYKR
       130        140        150        160        170        180
DCFSVGSNVD IDFSGPTIYG WAVLAFEGWL AGYQMSFDTA KSKLSQNNFA LGYKAADFQL
       190        200        210        220        230        240
HTHVNDGTEF GGSIYQKVNE KIETSINLAW TAGSNNTRFG IAAKYMLDCR TSLSAKVNNA
       250        260        270        280
SLIGLGYTQT LRPGVKLTLS ALIDGKNFSA GGHKVGLGFE LEA

Isoforms

- Isoform 2 of Voltage-dependent anion-selective channel protein 3

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
Q9Y277-2-unknown	MCNTPT...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y277-1-unknown	MCNTPT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94088
Q9Y277-2-Acetylation	CNTPTY...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y277-2-Acetylation	CNTPTY...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q9Y277-2-Acetylation	CNTPTY...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110648
Q9Y277-186-unknown	DGTEFG...	186		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18184
Q9Y277-186-unknown	DGTEFG...	186		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19874
Q9Y277-186-unknown	DGTEFG...	186		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146121
Q9Y277-186-unknown	DGTEFG...	186		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y277-186-unknown	DGTEFG...	186		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HTHVND	185	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18184
...HTHVND	185	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19874
...HTHVND	185	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129422
...FELEA	283	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FELEA	283	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89706

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	185	HVND.\|.DGTE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	185	HVND.\|.DGTE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)