Q99729: Heterogeneous nuclear ribonucleoprotein A/B

General Information

Protein names	- Heterogeneous nuclear ribonucleoprotein A/B - hnRNP A/B - APOBEC1-binding protein 1 - ABBP-1
Gene names	HNRNPAB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99729

7 N-termini

5 C-termini

5 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Heterogeneous nuclear ribonucleoprotein A/B - Isoform 3 of Heterogeneous nuclear ribonucleoprotein A/B - Isoform 4 of Heterogeneous nuclear ribonucleoprotein A/B

Sequence View

        10         20         30         40         50         60
MSEAGEEQPM ETTGATENGH EAVPEASRGR GWTGAAAGAG GATAAPPSGN QNGAEGDQIN
        70         80         90        100        110        120
ASKNEEDAGK MFVGGLSWDT SKKDLKDYFT KFGEVVDCTI KMDPNTGRSR GFGFILFKDA
       130        140        150        160        170        180
ASVEKVLDQK EHRLDGRVID PKKAMAMKKD PVKKIFVGGL NPESPTEEKI REYFGEFGEI
       190        200        210        220        230        240
EAIELPMDPK LNKRRGFVFI TFKEEEPVKK VLEKKFHTVS GSKCEIKVAQ PKEVYQQQQY
       250        260        270        280        290        300
GSGGRGNRNR GNRGSGGGGG GGGQSQSWNQ GYGNYWNQGY GYQQGYGPGY GGYDYSPYGY
       310        320        330
YGYGPGYDYS QGSTNYGKSQ RRGGHQNNYK PY         10         20         30         40         50         60
MSEAGEEQPM ETTGATENGH EAVPEASRGR GWTGAAAGAG GATAAPPSGN QNGAEGDQIN
        70         80         90        100        110        120
ASKNEEDAGK MFVGGLSWDT SKKDLKDYFT KFGEVVDCTI KMDPNTGRSR GFGFILFKDA
       130        140        150        160        170        180
ASVEKVLDQK EHRLDGRVID PKKAMAMKKD PVKKIFVGGL NPESPTEEKI REYFGEFGEI
       190        200        210        220        230        240
EAIELPMDPK LNKRRGFVFI TFKEEEPVKK VLEKKFHTVS GSKCEIKVAQ PKEVYQQQQY
       250        260        270        280        290        300
GSGGRGNRNR GNRGSGGGGG GGGQSQSWNQ GYGNYWNQGY GYQQGYGPGY GGYDYSPYGY
       310        320        330
YGYGPGYDYS QGSTNYGKSQ RRGGHQNNYK PY         10         20         30         40         50         60
MSEAGEEQPM ETTGATENGH EAVPEASRGR GWTGAAAGAG GATAAPPSGN QNGAEGDQIN
        70         80         90        100        110        120
ASKNEEDAGK MFVGGLSWDT SKKDLKDYFT KFGEVVDCTI KMDPNTGRSR GFGFILFKDA
       130        140        150        160        170        180
ASVEKVLDQK EHRLDGRVID PKKAMAMKKD PVKKIFVGGL NPESPTEEKI REYFGEFGEI
       190        200        210        220        230        240
EAIELPMDPK LNKRRGFVFI TFKEEEPVKK VLEKKFHTVS GSKCEIKVAQ PKEVYQQQQY
       250        260        270        280        290        300
GSGGRGNRNR GNRGSGGGGG GGGQSQSWNQ GYGNYWNQGY GYQQGYGPGY GGYDYSPYGY
       310        320        330
YGYGPGYDYS QGSTNYGKSQ RRGGHQNNYK PY

Filter Information:

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 5 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q99729-1-unknown	MSEAGE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99729-1-unknown	MSEAGE...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88056
Q99729-1-unknown	MSEAGE...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88057
Q99729-1-unknown	MSEAGE...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88058
Q99729-53-unknown	GAEGDQ...	53	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173948
Q99729-53-unknown	GAEGDQ...	53	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173949
Q99729-53-unknown	GAEGDQ...	53	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173950
Q99729-53-	GAEGDQ...	53		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q99729-53-	GAEGDQ...	53		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q99729-53-	GAEGDQ...	53		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q99729-72-unknown	FVGGLS...	72	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4213
Q99729-72-unknown	FVGGLS...	72	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt140833
Q99729-72-unknown	FVGGLS...	72	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt140834
Q99729-72-unknown	FVGGLS...	72	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt140835
Q99729-75-unknown	GLSWDT...	75	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4217
Q99729-75-unknown	GLSWDT...	75	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt141045
Q99729-75-unknown	GLSWDT...	75	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt141046
Q99729-75-unknown	GLSWDT...	75	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt141047
Q99729-157-unknown	VGGLNP...	157	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19747
Q99729-157-unknown	VGGLNP...	157	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18085
Q99729-157-unknown	VGGLNP...	157	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145058
Q99729-159-unknown	GLNPES...	159	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4221
Q99729-159-unknown	GLNPES...	159	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145136

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DAGKMF	71	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4213
...DAGKMF	71	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123972
...DAGKMF	71	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123973
...DAGKMF	71	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123974
...KMFVGG	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4217
...KMFVGG	74	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124195
...KMFVGG	74	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124196
...KMFVGG	74	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124197
...VKKIFV	156	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19747
...VKKIFV	156	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18085
...VKKIFV	156	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128341
...VKKIFV	156	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155037
...VKKIFV	156	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155038
...KIFVGG	158	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4221
...KIFVGG	158	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128423
...KIFVGG	158	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155071
...KIFVGG	158	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155072
...NYKPY	332	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...NYKPY	332	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83675
...NYKPY	332	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83676
...NYKPY	332	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83674

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	71	GKMF.\|.FVGG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	74	FVGG.\|.GLSW	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1B_HUMAN	156	KIFV.\|.VGGL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	156	KIFV.\|.VGGL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATB_HUMAN	158	FVGG.\|.GLNP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)