P31947: 14-3-3 protein sigma

General Information

Protein names	- 14-3-3 protein sigma - Epithelial cell marker protein 1 - Stratifin
Gene names	SFN
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P31947

10 N-termini

11 C-termini

13 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MERASLIQKA KLAEQAERYE DMAAFMKGAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR
        70         80         90        100        110        120
VLSSIEQKSN EEGSEEKGPE VREYREKVET ELQGVCDTVL GLLDSHLIKE AGDAESRVFY
       130        140        150        160        170        180
LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH
       190        200        210        220        230        240
YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADNAGEEGG

EAPQEPQS

Isoforms

- Isoform 2 of 14-3-3 protein sigma

Sequence View

        10         20         30         40         50         60
MERASLIQKA KLAEQAERYE DMAAFMKGAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR
        70         80         90        100        110        120
VLSSIEQKSN EEGSEEKGPE VREYREKVET ELQGVCDTVL GLLDSHLIKE AGDAESRVFY
       130        140        150        160        170        180
LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH
       190        200        210        220        230        240
YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADNAGEEGG

EAPQEPQS

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P31947-1-unknown	MERASL...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P31947-1-unknown	MERASL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65721
P31947-21-unknown	DMAAFM...	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19043
P31947-21-unknown	DMAAFM...	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17583
P31947-21-unknown	DMAAFM...	21	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt136919
P31947-25-unknown	FMKGAV...	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17585
P31947-25-unknown	FMKGAV...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt137206
P31947-26-unknown	MKGAVE...	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17587
P31947-26-unknown	MKGAVE...	26	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt137287
P31947-64-unknown	SIEQKS...	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17589
P31947-64-unknown	SIEQKS...	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140245
P31947-71-unknown	EEGSEE...	71	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19045
P31947-71-unknown	EEGSEE...	71	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17591
P31947-73-unknown	GSEEKG...	73	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19047
P31947-73-unknown	GSEEKG...	73	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17593
P31947-97-unknown	DTVLGL...	97	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19049
P31947-98-unknown	TVLGLL...	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19050
P31947-104-unknown	DSHLIK...	104	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19051
P31947-104-unknown	DSHLIK...	104	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17595

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...AERYED	20	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19043
...AERYED	20	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17583
...EDMAAF	24	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17585
...EDMAAF	24	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt120123
...DMAAFM	25	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17587
...DMAAFM	25	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt120219
...WRVLSS	63	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17589
...WRVLSS	63	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt123364
...EQKSNE	70	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19045
...EQKSNE	70	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17591
...EQKSNE	70	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt123859
...KSNEEG	72	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19047
...KSNEEG	72	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17593
...KSNEEG	72	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt123968
...LQGVCD	96	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19049
...QGVCDT	97	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19050
...VLGLLD	103	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19051
...VLGLLD	103	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17595
...QEPQS	248	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...QEPQS	248	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt61339
...QEPQS	248		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...QEPQS	248		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	20	RYED.\|.DMAA	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	20	RYED.\|.DMAA	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	24	MAAF.\|.FMKG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	25	AAFM.\|.MKGA	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	63	VLSS.\|.SIEQ	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	70	KSNE.\|.EEGS	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	70	KSNE.\|.EEGS	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	72	NEEG.\|.GSEE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	72	NEEG.\|.GSEE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	96	GVCD.\|.DTVL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	97	VCDT.\|.TVLG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	103	GLLD.\|.DSHL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	103	GLLD.\|.DSHL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

TopFIND

P31947: 14-3-3 protein sigma

General Information

10

N-termini

11

C-termini

13

Cleavages

0

Substrates

Sequence

Isoforms

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Protein Neighborhood

Domains & Features

10 N-termini - 11 C-termini - 13 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates