P08134: Rho-related GTP-binding protein RhoC

General Information

Protein names	- Rho-related GTP-binding protein RhoC - Rho cDNA clone 9 - h9
Gene names	RHOC
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P08134

7 N-termini

9 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYIADIEVDG KQVELALWDT
        70         80         90        100        110        120
AGQEDYDRLR PLSYPDTDVI LMCFSIDSPD SLENIPEKWT PEVKHFCPNV PIILVGNKKD
       130        140        150        160        170        180
LRQDEHTRRE LAKMKQEPVR SEEGRDMANR ISAFGYLECS AKTKEGVREV FEMATRAGLQ
       190
VRKNKRRRGC PIL

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 9 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P08134-1-unknown	MAAIRK...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P08134-18-unknown	KTCLLI...	18	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13940
P08134-60-unknown	TAGQED...	60	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5499
P08134-81-	LMCFSI...	81		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P08134-85-	SIDSPD...	85		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P08134-85-	SIDSPD...	85		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P08134-91-	SLENIP...	91		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P08134-91-	SLENIP...	91		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P08134-91-	SLENIP...	91		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P08134-91-	SLENIP...	91		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P08134-114-unknown	LVGNKK...	114	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17220

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DGACGK	17	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13940
...LALWDT	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5499
...DSPDSL	91	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000395791
...SPDSLE	92	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000434877
...NVPIIL	113	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17220
...QDEHTR	127	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399424
...EGVREV	169	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000436240
...NKRRRG	188	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000390823
...RRRGCP	190	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	17	ACGK.\|.KTCL	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CATL1_HUMAN	59	LWDT.\|.TAGQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	113	PIIL.\|.LVGN	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)