P19338: Nucleolin

General Information

Protein names	- Nucleolin - Protein C23
Gene names	NCL
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P19338

73 N-termini

25 C-termini

24 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVKLAKAGKN QGDPKKMAPP PKEVEEDSED EEMSEDEEDD SSGEEVVIPQ KKGKKAAATS
        70         80         90        100        110        120
AKKVVVSPTK KVAVATPAKK AAVTPGKKAA ATPAKKTVTP AKAVTTPGKK GATPGKALVA
       130        140        150        160        170        180
TPGKKGAAIP AKGAKNGKNA KKEDSDEEED DDSEEDEEDD EDEDEDEDEI EPAAMKAAAA
       190        200        210        220        230        240
APASEDEDDE DDEDDEDDDD DEEDDSEEEA METTPAKGKK AAKVVPVKAK NVAEDEDEEE
       250        260        270        280        290        300
DDEDEDDDDD EDDEDDDDED DEEEEEEEEE EPVKEAPGKR KKEMAKQKAA PEAKKQKVEG
       310        320        330        340        350        360
TEPTTAFNLF VGNLNFNKSA PELKTGISDV FAKNDLAVVD VRIGMTRKFG YVDFESAEDL
       370        380        390        400        410        420
EKALELTGLK VFGNEIKLEK PKGKDSKKER DARTLLAKNL PYKVTQDELK EVFEDAAEIR
       430        440        450        460        470        480
LVSKDGKSKG IAYIEFKTEA DAEKTFEEKQ GTEIDGRSIS LYYTGEKGQN QDYRGGKNST
       490        500        510        520        530        540
WSGESKTLVL SNLSYSATEE TLQEVFEKAT FIKVPQNQNG KSKGYAFIEF ASFEDAKEAL
       550        560        570        580        590        600
NSCNKREIEG RAIRLELQGP RGSPNARSQP SKTLFVKGLS EDTTEETLKE SFDGSVRARI
       610        620        630        640        650        660
VTDRETGSSK GFGFVDFNSE EDAKAAKEAM EDGEIDGNKV TLDWAKPKGE GGFGGRGGGR
       670        680        690        700        710
GGFGGRGGGR GGRGGFGGRG RGGFGGRGGF RGGRGGGGDH KPQGKKTKFE

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

73 N-termini - 25 C-termini - 24 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P19338-2-unknown	VKLAKA...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P19338-17-unknown	MAPPPK...	17	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P19338-17-unknown	MAPPPK...	17	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P19338-17-unknown	MAPPPK...	17	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000401620
P19338-17-unknown	MAPPPK...	17	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000392747
P19338-17-unknown	MAPPPK...	17	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000413775
P19338-17-unknown	MAPPPK...	17	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000401322
P19338-63-unknown	KVVVSP...	63		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-63-unknown	KVVVSP...	63		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-63-	KVVVSP...	63		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P19338-63-	KVVVSP...	63		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P19338-71-unknown	KVAVAT...	71		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-71-	KVAVAT...	71		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P19338-72-unknown	VAVATP...	72		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-72-	VAVATP...	72		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P19338-72-	VAVATP...	72		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P19338-72-	VAVATP...	72		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P19338-72-	VAVATP...	72		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P19338-72-	VAVATP...	72		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P19338-72-	VAVATP...	72		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P19338-72-	VAVATP...	72		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-80-unknown	KAAVTP...	80		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-81-unknown	AAVTPG...	81		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-81-	AAVTPG...	81		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P19338-81-	AAVTPG...	81		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-89-unknown	AAATPA...	89		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-89-	AAATPA...	89		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P19338-97-unknown	TVTPAK...	97	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P19338-97-unknown	TVTPAK...	97	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P19338-97-unknown	TVTPAK...	97		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-97-unknown	TVTPAK...	97		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-97-	TVTPAK...	97		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P19338-97-	TVTPAK...	97		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P19338-97-	TVTPAK...	97		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P19338-97-	TVTPAK...	97		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-97-	TVTPAK...	97		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-103-	AVTTPG...	103		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-111-unknown	GATPGK...	111		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-111-	GATPGK...	111		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P19338-111-	GATPGK...	111		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P19338-111-	GATPGK...	111		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P19338-117-unknown	ALVATP...	117		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-117-	ALVATP...	117		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P19338-125-	KGAAIP...	125		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P19338-179-	AAAPAS...	179		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P19338-180-	AAPASE...	180		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P19338-221-	AAKVVP...	221		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P19338-221-	AAKVVP...	221		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P19338-224-	VVPVKA...	224		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-268-unknown	EEEEPV...	268	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18833
P19338-350-	GYVDFE...	350		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-350-	GYVDFE...	350		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P19338-353-unknown	DFESAE...	353	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5647
P19338-394-	TLLAKN...	394		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P19338-394-	TLLAKN...	394		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P19338-399-	NLPYKV...	399		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P19338-399-	NLPYKV...	399		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P19338-399-	NLPYKV...	399		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-400-unknown	LPYKVT...	400	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000349410
P19338-402-	YKVTQD...	402		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-403-	KVTQDE...	403		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-403-	KVTQDE...	403		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P19338-404-	VTQDEL...	404		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-404-	VTQDEL...	404		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P19338-404-	VTQDEL...	404		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-407-unknown	DELKEV...	407	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17419
P19338-407-unknown	DELKEV...	407	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18834
P19338-408-unknown	ELKEVF...	408	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11312
P19338-409-unknown	LKEVFE...	409	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11313
P19338-412-	VFEDAA...	412		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-428-unknown	SKGIAY...	428	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P19338-428-unknown	SKGIAY...	428	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P19338-428-unknown	SKGIAY...	428		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-428-	SKGIAY...	428		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P19338-428-	SKGIAY...	428		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P19338-430-unknown	GIAYIE...	430	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11314
P19338-430-	GIAYIE...	430		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P19338-430-	GIAYIE...	430		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-430-	GIAYIE...	430		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P19338-430-	GIAYIE...	430		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P19338-430-	GIAYIE...	430		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-433-unknown	YIEFKT...	433	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11315
P19338-436-unknown	FKTEAD...	436	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11316
P19338-442-unknown	AEKTFE...	442	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11317
P19338-445-	TFEEKQ...	445		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-456-unknown	GRSISL...	456	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1680
P19338-458-unknown	SISLYY...	458		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-458-	SISLYY...	458		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P19338-458-	SISLYY...	458		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P19338-458-	SISLYY...	458		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-458-	SISLYY...	458		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P19338-458-	SISLYY...	458		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P19338-458-	SISLYY...	458		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-462-unknown	YYTGEK...	462		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19338-468-	GQNQDY...	468		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-475-	GGKNST...	475		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P19338-475-	GGKNST...	475		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-479-	STWSGE...	479		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-491-	SNLSYS...	491		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P19338-494-	SYSATE...	494		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P19338-494-	SYSATE...	494		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-494-	SYSATE...	494		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P19338-494-	SYSATE...	494		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P19338-494-	SYSATE...	494		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P19338-494-	SYSATE...	494		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-496-	SATEET...	496		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-496-	SATEET...	496		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P19338-496-	SATEET...	496		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P19338-496-	SATEET...	496		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P19338-497-	ATEETL...	497		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-527-unknown	FIEFAS...	527	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17420
P19338-534-unknown	EDAKEA...	534	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17421
P19338-534-unknown	EDAKEA...	534	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18835
P19338-573-	TLFVKG...	573		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P19338-573-	TLFVKG...	573		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P19338-576-unknown	VKGLSE...	576	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17422
P19338-578-	GLSEDT...	578		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P19338-578-	GLSEDT...	578		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P19338-578-	GLSEDT...	578		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P19338-578-	GLSEDT...	578		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P19338-578-	GLSEDT...	578		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-578-	GLSEDT...	578		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P19338-578-	GLSEDT...	578		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P19338-578-	GLSEDT...	578		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P19338-578-	GLSEDT...	578		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P19338-578-	GLSEDT...	578		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-581-unknown	EDTTEE...	581	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7355
P19338-582-unknown	DTTEET...	582	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17423
P19338-582-unknown	DTTEET...	582	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18836
P19338-583-unknown	TTEETL...	583	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11318
P19338-611-	GFGFVD...	611		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P19338-611-	GFGFVD...	611		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-611-	GFGFVD...	611		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P19338-611-	GFGFVD...	611		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P19338-611-	GFGFVD...	611		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-613-	GFVDFN...	613		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-613-	GFVDFN...	613		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P19338-614-unknown	FVDFNS...	614	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5648
P19338-614-unknown	FVDFNS...	614	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3676
P19338-614-unknown	FVDFNS...	614	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7356
P19338-614-	FVDFNS...	614		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-633-unknown	GEIDGN...	633	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1681
P19338-637-unknown	GNKVTL...	637	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1682
P19338-637-	GNKVTL...	637		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19338-637-	GNKVTL...	637		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P19338-706-	KTKFE...	706		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SEEDEE	157	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000401322
...EDEDED	167	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000413775
...AAAAPA	182	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000392747
...PASEDE	186	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000401620
...EEEEEE	267	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18833
...KFGYVD	352	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5647
...YKVTQD	406	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17419
...YKVTQD	406	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18834
...KVTQDE	407	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11312
...VTQDEL	408	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11313
...DGKSKG	429	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11314
...SKGIAY	432	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11315
...IAYIEF	435	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11316
...KTEADA	441	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11317
...GTEIDG	455	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1680
...SKGYAF	526	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17420
...EFASFE	533	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17421
...EFASFE	533	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18835
...SKTLFV	575	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17422
...VKGLSE	580	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7355
...KGLSED	581	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17423
...KGLSED	581	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18836
...GLSEDT	582	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11318
...SKGFGF	613	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5648
...SKGFGF	613	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3676
...SKGFGF	613	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7356
...EAMEDG	632	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1681
...DGEIDG	636	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1682
...GGGRGG	671	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000349410
...KTKFE	710	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	267	EEEE.\|.EEEE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	352	GYVD.\|.DFES	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	406	VTQD.\|.DELK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	406	VTQD.\|.DELK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAB_HUMAN	407	TQDE.\|.ELKE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_HUMAN	408	QDEL.\|.LKEV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	429	KSKG.\|.GIAY	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	432	GIAY.\|.YIEF	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	435	YIEF.\|.FKTE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_HUMAN	441	EADA.\|.AEKT	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
CASP3_HUMAN	455	EIDG.\|.GRSI	inferred from experiment	unknown	MEROPS	Rudel T	Thiede B et al.:Predominant identification of R... (C14.003)	11352910,
MEP1A_HUMAN	526	GYAF.\|.FIEF	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	533	ASFE.\|.EDAK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	533	ASFE.\|.EDAK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	575	TLFV.\|.VKGL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATS_HUMAN	580	GLSE.\|.EDTT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	581	LSED.\|.DTTE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	581	LSED.\|.DTTE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAB_HUMAN	582	SEDT.\|.TTEE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
CATL1_HUMAN	613	GFGF.\|.FVDF	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	613	GFGF.\|.FVDF	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	613	GFGF.\|.FVDF	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CASP3_HUMAN	632	MEDG.\|.GEID	inferred from experiment	unknown	MEROPS	Rudel T	Thiede B et al.:Predominant identification of R... (C14.003)	11352910,
CASP3_HUMAN	636	EIDG.\|.GNKV	inferred from experiment	unknown	MEROPS	Rudel T	Thiede B et al.:Predominant identification of R... (C14.003)	11352910,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)