Q9ULZ3: Apoptosis-associated speck-like protein containing a CARD

General Information

Protein names	- Apoptosis-associated speck-like protein containing a CARD - hASC - Caspase recruitment domain-containing protein 5 - PYD and CARD domain-containing protein - Target of methylation-induced silencing 1
Gene names	PYCARD
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9ULZ3

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Apoptosis-associated speck-like protein containing a CARD - Isoform 3 of Apoptosis-associated speck-like protein containing a CARD

Sequence View

        10         20         30         40         50         60
MGRARDAILD ALENLTAEEL KKFKLKLLSV PLREGYGRIP RGALLSMDAL DLTDKLVSFY
        70         80         90        100        110        120
LETYGAELTA NVLRDMGLQE MAGQLQAATH QGSGAAPAGI QAPPQSAAKP GLHFIDQHRA
       130        140        150        160        170        180
ALIARVTNVE WLLDALYGKV LTDEQYQAVR AEPTNPSKMR KLFSFTPAWN WTCKDLLLQA
       190
LRESQSYLVE DLERS         10         20         30         40         50         60
MGRARDAILD ALENLTAEEL KKFKLKLLSV PLREGYGRIP RGALLSMDAL DLTDKLVSFY
        70         80         90        100        110        120
LETYGAELTA NVLRDMGLQE MAGQLQAATH QGSGAAPAGI QAPPQSAAKP GLHFIDQHRA
       130        140        150        160        170        180
ALIARVTNVE WLLDALYGKV LTDEQYQAVR AEPTNPSKMR KLFSFTPAWN WTCKDLLLQA
       190
LRESQSYLVE DLERS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9ULZ3-1-unknown	MGRARD...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9ULZ3-1-unknown	MGRARD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt67623
Q9ULZ3-1-unknown	MGRARD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt67624
Q9ULZ3-107-unknown	AAKPGL...	107	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18169
Q9ULZ3-107-unknown	AAKPGL...	107	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt138938

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...APPQSA	106	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18169
...APPQSA	106	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122005
...DLERS	195	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DLERS	195	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt63242
...DLERS	195	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt63241

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	106	PQSA.\|.AAKP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)