Q09666: Neuroblast differentiation-associated protein AHNAK

General Information

Protein names	- Neuroblast differentiation-associated protein AHNAK - Desmoyokin
Gene names	AHNAK
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q09666

52 N-termini

13 C-termini

15 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEKEETTREL LLPNWQGSGS HGLTIAQRDD GVFVQEVTQN SPAARTGVVK EGDQIVGATI
        70         80         90        100        110        120
YFDNLQSGEV TQLLNTMGHH TVGLKLHRKG DRSPEPGQTW TREVFSSCSS EVVLSGDDEE
       130        140        150        160        170        180
YQRIYTTKIK PRLKSEDGVE GDLGETQSRT ITVTRRVTAY TVDVTGREGA KDIDISSPEF
       190        200        210        220        230        240
KIKIPRHELT EISNVDVETQ SGKTVIRLPS GSGAASPTGS AVDIRAGAIS ASGPELQGAG
       250        260        270        280        290        300
HSKLQVTMPG IKVGGSGVNV NAKGLDLGGR GGVQVPAVDI SSSLGGRAVE VQGPSLESGD
       310        320        330        340        350        360
HGKIKFPTMK VPKFGVSTGR EGQTPKAGLR VSAPEVSVGH KGGKPGLTIQ APQLEVSVPS
       370        380        390        400        410        420
ANIEGLEGKL KGPQITGPSL EGDLGLKGAK PQGHIGVDAS APQIGGSITG PSVEVQAPDI
       430        440        450        460        470        480
DVQGPGSKLN VPKMKVPKFS VSGAKGEETG IDVTLPTGEV TVPGVSGDVS LPEIATGGLE
       490        500        510        520        530        540
GKMKGTKVKT PEMIIQKPKI SMQDVDLSLG SPKLKGDIKV SAPGVQGDVK GPQVALKGSR
       550        560        570        580        590        600
VDIETPNLEG TLTGPRLGSP SGKTGTCRIS MSEVDLNVAA PKVKGGVDVT LPRVEGKVKV
       610        620        630        640        650        660
PEVDVRGPKV DVSAPDVEAH GPEWNLKMPK MKMPTFSTPG AKGEGPDVHM TLPKGDISIS
       670        680        690        700        710        720
GPKVNVEAPD VNLEGLGGKL KGPDVKLPDM SVKTPKISMP DVDLHVKGTK VKGEYDVTVP
       730        740        750        760        770        780
KLEGELKGPK VDIDAPDVDV HGPDWHLKMP KMKMPKFSVP GFKAEGPEVD VNLPKADVDI
       790        800        810        820        830        840
SGPKIDVTAP DVSIEEPEGK LKGPKFKMPE MNIKVPKISM PDVDLHLKGP NVKGEYDVTM
       850        860        870        880        890        900
PKVESEIKVP DVELKSAKMD IDVPDVEVQG PDWHLKMPKM KMPKFSMPGF KAEGPEVDVN
       910        920        930        940        950        960
LPKADVDISG PKVGVEVPDV NIEGPEGKLK GPKFKMPEMN IKAPKISMPD VDLHMKGPKV
       970        980        990       1000       1010       1020
KGEYDMTVPK LEGDLKGPKV DVSAPDVEMQ GPDWNLKMPK IKMPKFSMPS LKGEGPEFDV
      1030       1040       1050       1060       1070       1080
NLSKANVDIS APKVDTNAPD LSLEGPEGKL KGPKFKMPEM HFRAPKMSLP DVDLDLKGPK
      1090       1100       1110       1120       1130       1140
MKGNVDISAP KIEGEMQVPD VDIRGPKVDI KAPDVEGQGL DWSLKIPKMK MPKFSMPSLK
      1150       1160       1170       1180       1190       1200
GEGPEVDVNL PKADVVVSGP KVDIEAPDVS LEGPEGKLKG PKFKMPEMHF KTPKISMPDV
      1210       1220       1230       1240       1250       1260
DLHLKGPKVK GDVDVSVPKV EGEMKVPDVE IKGPKMDIDA PDVEVQGPDW HLKMPKMKMP
      1270       1280       1290       1300       1310       1320
KFSMPGFKGE GREVDVNLPK ADIDVSGPKV DVEVPDVSLE GPEGKLKGPK FKMPEMHFKA
      1330       1340       1350       1360       1370       1380
PKISMPDVDL NLKGPKLKGD VDVSLPEVEG EMKVPDVDIK GPKVDISAPD VDVHGPDWHL
      1390       1400       1410       1420       1430       1440
KMPKVKMPKF SMPGFKGEGP EVDVKLPKAD VDVSGPKMDA EVPDVNIEGP DAKLKGPKFK
      1450       1460       1470       1480       1490       1500
MPEMSIKPQK ISIPDVGLHL KGPKMKGDYD VTVPKVEGEI KAPDVDIKGP KVDINAPDVE
      1510       1520       1530       1540       1550       1560
VHGPDWHLKM PKVKMPKFSM PGFKGEGPEV DMNLPKADLG VSGPKVDIDV PDVNLEAPEG
      1570       1580       1590       1600       1610       1620
KLKGPKFKMP SMNIQTHKIS MPDVGLNLKA PKLKTDVDVS LPKVEGDLKG PEIDVKAPKM
      1630       1640       1650       1660       1670       1680
DVNVGDIDIE GPEGKLKGPK FKMPEMHFKA PKISMPDVDL HLKGPKVKGD MDVSVPKVEG
      1690       1700       1710       1720       1730       1740
EMKVPDVDIK GPKVDIDAPD VEVHDPDWHL KMPKMKMPKF SMPGFKAEGP EVDVNLPKAD
      1750       1760       1770       1780       1790       1800
IDVSGPSVDT DAPDLDIEGP EGKLKGSKFK MPKLNIKAPK VSMPDVDLNL KGPKLKGEID
      1810       1820       1830       1840       1850       1860
ASVPELEGDL RGPQVDVKGP FVEAEVPDVD LECPDAKLKG PKFKMPEMHF KAPKISMPDV
      1870       1880       1890       1900       1910       1920
DLHLKGPKVK GDADVSVPKL EGDLTGPSVG VEVPDVELEC PDAKLKGPKF KMPDMHFKAP
      1930       1940       1950       1960       1970       1980
KISMPDVDLH LKGPKVKGDV DVSVPKLEGD LTGPSVGVEV PDVELECPDA KLKGPKFKMP
      1990       2000       2010       2020       2030       2040
EMHFKTPKIS MPDVDLHLKG PKVKGDMDVS VPKVEGEMKV PDVDIKGPKM DIDAPDVDVH
      2050       2060       2070       2080       2090       2100
GPDWHLKMPK MKMPKFSMPG FKAEGPEVDV NLPKADVVVS GPKVDVEVPD VSLEGPEGKL
      2110       2120       2130       2140       2150       2160
KGPKLKMPEM HFKAPKISMP DVDLHLKGPK VKGDVDVSLP KLEGDLTGPS VDVEVPDVEL
      2170       2180       2190       2200       2210       2220
ECPDAKLKGP KFKMPEMHFK TPKISMPDVN LNLKGPKVKG DMDVSVPKVE GEMKVPDVDI
      2230       2240       2250       2260       2270       2280
RGPKVDIDAP DVDVHGPDWH LKMPKMKMPK FSMPGFKGEG PEVDVNLPKA DVDVSGPKVD
      2290       2300       2310       2320       2330       2340
VEVPDVSLEG PEGKLKGPKF KMPEMHFKTP KISMPDVDFN LKGPKIKGDV DVSAPKLEGE
      2350       2360       2370       2380       2390       2400
LKGPELDVKG PKLDADMPEV AVEGPNGKWK TPKFKMPDMH FKAPKISMPD LDLHLKSPKA
      2410       2420       2430       2440       2450       2460
KGEVDVDVPK LEGDLKGPHV DVSGPDIDIE GPEGKLKGPK FKMPDMHFKA PNISMPDVDL
      2470       2480       2490       2500       2510       2520
NLKGPKIKGD VDVSVPEVEG KLEVPDMNIR GPKVDVNAPD VQAPDWHLKM PKMKMPKFSM
      2530       2540       2550       2560       2570       2580
PGFKAEGPEV DVNLPKADVD ISGPKVDIEG PDVNIEGPEG KLKGPKLKMP EMNIKAPKIS
      2590       2600       2610       2620       2630       2640
MPDFDLHLKG PKVKGDVDVS LPKVEGDLKG PEVDIKGPKV DINAPDVGVQ GPDWHLKMPK
      2650       2660       2670       2680       2690       2700
VKMPKFSMPG FKGEGPDGDV KLPKADIDVS GPKVDIEGPD VNIEGPEGKL KGPKFKMPEM
      2710       2720       2730       2740       2750       2760
NIKAPKISMP DIDLNLKGPK VKGDVDVSLP KVEGDLKGPE VDIKGPKVDI DAPDVDVHGP
      2770       2780       2790       2800       2810       2820
DWHLKMPKIK MPKISMPGFK GEGPDVDVNL PKADIDVSGP KVDVECPDVN IEGPEGKWKS
      2830       2840       2850       2860       2870       2880
PKFKMPEMHF KTPKISMPDI DLNLTGPKIK GDVDVTGPKV EGDLKGPEVD LKGPKVDIDV
      2890       2900       2910       2920       2930       2940
PDVNVQGPDW HLKMPKMKMP KFSMPGFKAE GPEVDVNLPK ADVDVSGPKV DVEGPDVNIE
      2950       2960       2970       2980       2990       3000
GPEGKLKGPK FKMPEMNIKA PKIPMPDFDL HLKGPKVKGD VDISLPKVEG DLKGPEVDIR
      3010       3020       3030       3040       3050       3060
GPQVDIDVPD VGVQGPDWHL KMPKVKMPKF SMPGFKGEGP DVDVNLPKAD LDVSGPKVDI
      3070       3080       3090       3100       3110       3120
DVPDVNIEGP EGKLKGPKFK MPEMNIKAPK ISMPDIDLNL KGPKVKGDMD VSLPKVEGDM
      3130       3140       3150       3160       3170       3180
KVPDVDIKGP KVDINAPDVD VQGPDWHLKM PKIKMPKISM PGFKGEGPEV DVNLPKADLD
      3190       3200       3210       3220       3230       3240
VSGPKVDVDV PDVNIEGPDA KLKGPKFKMP EMNIKAPKIS MPDLDLNLKG PKMKGEVDVS
      3250       3260       3270       3280       3290       3300
LANVEGDLKG PALDIKGPKI DVDAPDIDIH GPDAKLKGPK LKMPDMHVNM PKISMPEIDL
      3310       3320       3330       3340       3350       3360
NLKGSKLKGD VDVSGPKLEG DIKAPSLDIK GPEVDVSGPK LNIEGKSKKS RFKLPKFNFS
      3370       3380       3390       3400       3410       3420
GSKVQTPEVD VKGKKPDIDI TGPKVDINAP DVEVQGKVKG SKFKMPFLSI SSPKVSMPDV
      3430       3440       3450       3460       3470       3480
ELNLKSPKVK GDLDIAGPNL EGDFKGPKVD IKAPEVNLNA PDVDVHGPDW NLKMPKMKMP
      3490       3500       3510       3520       3530       3540
KFSVSGLKAE GPDVAVDLPK GDINIEGPSM NIEGPDLNVE GPEGGLKGPK FKMPDMNIKA
      3550       3560       3570       3580       3590       3600
PKISMPDIDL NLKGPKVKGD VDISLPKLEG DLKGPEVDIK GPKVDINAPD VDVHGPDWHL
      3610       3620       3630       3640       3650       3660
KMPKVKMPKF SMPGFKGEGP EVDVTLPKAD IDISGPNVDV DVPDVNIEGP DAKLKGPKFK
      3670       3680       3690       3700       3710       3720
MPEMNIKAPK ISMPDFDLNL KGPKMKGDVV VSLPKVEGDL KGPEVDIKGP KVDIDTPDIN
      3730       3740       3750       3760       3770       3780
IEGSEGKFKG PKFKIPEMHL KAPKISMPDI DLNLKGPKVK GDVDVSLPKM EGDLKGPEVD
      3790       3800       3810       3820       3830       3840
IKGPKVDINA PDVDVQGPDW HLKMPKVKMP KFSMPGFKGE GPDVDVNLPK ADLDVSGPKV
      3850       3860       3870       3880       3890       3900
DIDVPDVNIE GPEGKLKGPK FKMPEMNIKA PKISMPDIDL NLKGPKVKGD MDVSLPKVEG
      3910       3920       3930       3940       3950       3960
DMQVPDLDIK GPKVDINAPD VDVRGPDWHL KMPKIKMPKI SMPGFKGEGP EVDVNLPKAD
      3970       3980       3990       4000       4010       4020
LDVSGPKVDV DVPDVNIEGP DAKLKGPKFK MPEMNIKAPK ISMPDFDLHL KGPKVKGDVD
      4030       4040       4050       4060       4070       4080
VSLPKMEGDL KAPEVDIKGP KVDIDAPDVD VHGPDWHLKM PKVKMPKFSM PGFKGEGPEV
      4090       4100       4110       4120       4130       4140
DVNLPKADID VSGPKVDIDT PDIDIHGPEG KLKGPKFKMP DLHLKAPKIS MPEVDLNLKG
      4150       4160       4170       4180       4190       4200
PKMKGDVDVS LPKVEGDLKG PEVDIKGPKV DIDVPDVDVQ GPDWHLKMPK VKMPKFSMPG
      4210       4220       4230       4240       4250       4260
FKGEGPDVDV NLPKADLDVS GPKVDIDVPD VNIEGPDAKL KGPKFKMPEM NIKAPKISMP
      4270       4280       4290       4300       4310       4320
DFDLHLKGPK VKGDVDVSLP KVEGDLKGPE VDIKGPKVDI DAPDVDVHGP DWHLKMPKVK
      4330       4340       4350       4360       4370       4380
MPKFSMPGFK GEGPDVDVTL PKADIEISGP KVDIDAPDVS IEGPDAKLKG PKFKMPEMNI
      4390       4400       4410       4420       4430       4440
KAPKISMPDI DFNLKGPKVK GDVDVSLPKV EGDLKGPEID IKGPSLDIDT PDVNIEGPEG
      4450       4460       4470       4480       4490       4500
KLKGPKFKMP EMNIKAPKIS MPDFDLHLKG PKVKGDVDVS LPKVESDLKG PEVDIEGPEG
      4510       4520       4530       4540       4550       4560
KLKGPKFKMP DVHFKSPQIS MSDIDLNLKG PKIKGDMDIS VPKLEGDLKG PKVDVKGPKV
      4570       4580       4590       4600       4610       4620
GIDTPDIDIH GPEGKLKGPK FKMPDLHLKA PKISMPEVDL NLKGPKVKGD MDISLPKVEG
      4630       4640       4650       4660       4670       4680
DLKGPEVDIR DPKVDIDVPD VDVQGPDWHL KMPKVKMPKF SMPGFKGEGP DVDVNLPKAD
      4690       4700       4710       4720       4730       4740
IDVSGPKVDV DVPDVNIEGP DAKLKGPKFK MPEMSIKAPK ISMPDIDLNL KGPKVKGDVD
      4750       4760       4770       4780       4790       4800
VTLPKVEGDL KGPEADIKGP KVDINTPDVD VHGPDWHLKM PKVKMPKFSM PGFKGEGPDV
      4810       4820       4830       4840       4850       4860
DVSLPKADID VSGPKVDVDI PDVNIEGPDA KLKGPKFKMP EINIKAPKIS IPDVDLDLKG
      4870       4880       4890       4900       4910       4920
PKVKGDFDVS VPKVEGTLKG PEVDLKGPRL DFEGPDAKLS GPSLKMPSLE ISAPKVTAPD
      4930       4940       4950       4960       4970       4980
VDLHLKAPKI GFSGPKLEGG EVDLKGPKVE APSLDVHMDS PDINIEGPDV KIPKFKKPKF
      4990       5000       5010       5020       5030       5040
GFGAKSPKAD IKSPSLDVTV PEAELNLETP EISVGGKGKK SKFKMPKIHM SGPKIKAKKQ
      5050       5060       5070       5080       5090       5100
GFDLNVPGGE IDASLKAPDV DVNIAGPDAA LKVDVKSPKT KKTMFGKMYF PDVEFDIKSP
      5110       5120       5130       5140       5150       5160
KFKAEAPLPS PKLEGELQAP DLELSLPAIH VEGLDIKAKA PKVKMPDVDI SVPKIEGDLK
      5170       5180       5190       5200       5210       5220
GPKVQANLGA PDINIEGLDA KVKTPSFGIS APQVSIPDVN VNLKGPKIKG DVPSVGLEGP
      5230       5240       5250       5260       5270       5280
DVDLQGPEAK IKFPKFSMPK IGIPGVKMEG GGAEVHAQLP SLEGDLRGPD VKLEGPDVSL
      5290       5300       5310       5320       5330       5340
KGPGVDLPSV NLSMPKVSGP DLDLNLKGPS LKGDLDASVP SMKVHAPGLN LSGVGGKMQV
      5350       5360       5370       5380       5390       5400
GGDGVKVPGI DATTKLNVGA PDVTLRGPSL QGDLAVSGDI KCPKVSVGAP DLSLEASEGS
      5410       5420       5430       5440       5450       5460
IKLPKMKLPQ FGISTPGSDL HVNAKGPQVS GELKGPGVDV NLKGPRISAP NVDFNLEGPK
      5470       5480       5490       5500       5510       5520
VKGSLGATGE IKGPTVGGGL PGIGVQGLEG NLQMPGIKSS GCDVNLPGVN VKLPTGQISG
      5530       5540       5550       5560       5570       5580
PEIKGGLKGS EVGFHGAAPD ISVKGPAFNM ASPESDFGIN LKGPKIKGGA DVSGGVSAPD
      5590       5600       5610       5620       5630       5640
ISLGEGHLSV KGSGGEWKGP QVSSALNLDT SKFAGGLHFS GPKVEGGVKG GQIGLQAPGL
      5650       5660       5670       5680       5690       5700
SVSGPQGHLE SGSGKVTFPK MKIPKFTFSG RELVGREMGV DVHFPKAEAS IQAGAGDGEW
      5710       5720       5730       5740       5750       5760
EESEVKLKKS KIKMPKFNFS KPKGKGGVTG SPEASISGSK GDLKSSKASL GSLEGEAEAE
      5770       5780       5790       5800       5810       5820
ASSPKGKFSL FKSKKPRHRS NSFSDEREFS GPSTPTGTLE FEGGEVSLEG GKVKGKHGKL
      5830       5840       5850       5860       5870       5880
KFGTFGGLGS KSKGHYEVTG SDDETGKLQG SGVSLASKKS RLSSSSSNDS GNKVGIQLPE
      5890
VELSVSTKKE

Isoforms

- Isoform 2 of Neuroblast differentiation-associated protein AHNAK

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

52 N-termini - 13 C-termini - 15 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q09666-1-Acetylation	MEKEET...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q09666-1-Acetylation	MEKEET...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q09666-1-Acetylation	MEKEET...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt103415
Q09666-1-Acetylation	MEKEET...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q09666-1-unknown	MEKEET...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt66543
Q09666-173-unknown	IDISSP...	173		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19377
Q09666-173-unknown	IDISSP...	173		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17867
Q09666-195-unknown	VDVETQ...	195		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19378
Q09666-311-	VPKFGV...	311			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-436-	VPKFSV...	436			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-528-unknown	DVKGPQ...	528		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19379
Q09666-580-unknown	APKVKG...	580		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19380
Q09666-580-unknown	APKVKG...	580		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17868
Q09666-583-	VKGGVD...	583			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-598-	VKVPEV...	598			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-631-	MKMPTF...	631			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-711-	VKGEYD...	711			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-738-	VDVHGP...	738			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-740-	VHGPDW...	740			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-742-unknown	GPDWHL...	742		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17869
Q09666-866-	VEVQGP...	866			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-882-	MPKFSM...	882			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-882-	MPKFSM...	882			Subtiligase Based Positive Selection		Wells	RMPI_untreated	23264352
Q09666-920-	VNIEGP...	920			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q09666-1003-	MPKFSM...	1003			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-1195-	ISMPDV...	1195			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-1197-unknown	MPDVDL...	1197		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17870
Q09666-1214-unknown	DVSVPK...	1214		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19381
Q09666-1214-unknown	DVSVPK...	1214		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17871
Q09666-1245-unknown	VQGPDW...	1245		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17872
Q09666-1371-unknown	VDVHGP...	1371		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19382
Q09666-1425-	VNIEGP...	1425			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q09666-1425-	VNIEGP...	1425			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q09666-1486-unknown	DIKGPK...	1486		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19383
Q09666-1584-	VGLNLK...	1584			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-1593-	LKTDVD...	1593			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-1650-	APKISM...	1650			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-1816-unknown	DVKGPF...	1816		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17873
Q09666-2131-	VKGDVD...	2131			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-2491-	GPKVDV...	2491			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-2604-	VEGDLK...	2604			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-2704-	APKISM...	2704			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-2712-	IDLNLK...	2712			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-2771-	MPKISM...	2771			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-2883-	VNVQGP...	2883			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-2960-	APKIPM...	2960			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-3105-	VKGDMD...	3105			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-3158-	ISMPGF...	3158			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-3465-	VHGPDW...	3465			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-3479-	MPKFSV...	3479			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-3719-	INIEGS...	3719			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q09666-5143-	VKMPDV...	5143			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-5236-	FSMPKI...	5236			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-5406-	MKLPQF...	5406			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-5525-	GGLKGS...	5525			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-5581-	ISLGEG...	5581			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-5690-	SIQAGA...	5690			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q09666-5820-	LKFGTF...	5820			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-5824-	TFGGLG...	5824			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q09666-5843-unknown	DETGKL...	5843		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19384

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EGAKDI	172	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19377
...EGAKDI	172	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17867
...TEISNV	194	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19378
...PGVQGD	527	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19379
...DLNVAA	579	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19380
...DLNVAA	579	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17868
...DVDVHG	741	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17869
...TPKISM	1196	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17870
...VKGDVD	1213	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19381
...VKGDVD	1213	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17871
...APDVEV	1244	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17872
...ISAPDV	1370	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19382
...KAPDVD	1485	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19383
...RGPQVD	1815	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17873
...VTGSDD	5842	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19384
...STKKE	5890	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	172	AKDI.\|.IDIS	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	172	AKDI.\|.IDIS	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	194	ISNV.\|.VDVE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	527	VQGD.\|.DVKG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	579	NVAA.\|.APKV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	579	NVAA.\|.APKV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	741	DVHG.\|.GPDW	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	1196	KISM.\|.MPDV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	1213	GDVD.\|.DVSV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	1213	GDVD.\|.DVSV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	1244	DVEV.\|.VQGP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	1370	APDV.\|.VDVH	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	1485	PDVD.\|.DIKG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	1815	PQVD.\|.DVKG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	5842	GSDD.\|.DETG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)