P29590: Protein PML
Protein names | - Protein PML - Promyelocytic leukemia protein - RING finger protein 71 - Tripartite motif-containing protein 19 |
---|---|
Gene names | PML |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P29590 |
12
N-termini
6
C-termini
6
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MEPAPARSPR PQQDPARPQE PTMPPPETPS EGRQPSPSPS PTERAPASEE EFQFLRCQQC
70 80 90 100 110 120
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR
130 140 150 160 170 180
QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG
190 200 210 220 230 240
TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEEL
250 260 270 280 290 300
DAMTQALQEQ DSAFGAVHAQ MHAAVGQLGR ARAETEELIR ERVRQVVAHV RAQERELLEA
310 320 330 340 350 360
VDARYQRDYE EMASRLGRLD AVLQRIRTGS ALVQRMKCYA SDQEVLDMHG FLRQALCRLR
370 380 390 400 410 420
QEEPQSLQAA VRTDGFDEFK VRLQDLSSCI TQGKDAAVSK KASPEAASTP RDPIDVDLPE
430 440 450 460 470 480
EAERVKAQVQ ALGLAEAQPM AVVQSVPGAH PVPVYAFSIK GPSYGEDVSN TTTAQKRKCS
490 500 510 520 530 540
QTQCPRKVIK MESEEGKEAR LARSSPEQPR PSTSKAVSPP HLDGPPSPRS PVIGSEVFLP
550 560 570 580 590 600
NSNHVASGAG EAEERVVVIS SSEDSDAENS SSRELDDSSS ESSDLQLEGP STLRVLDENL
610 620 630 640 650 660
ADPQAEDRPL VFFDLKIDNE TQKISQLAAV NRESKFRVVI QPEAFFSIYS KAVSLEVGLQ
670 680 690 700 710 720
HFLSFLSSMR RPILACYKLW GPGLPNFFRA LEDINRLWEF QEAISGFLAA LPLIRERVPG
730 740 750 760 770 780
ASSFKLKNLA QTYLARNMSE RSAMAAVLAM RDLCRLLEVS PGPQLAQHVY PFSSLQCFAS
790 800 810 820 830 840
LQPLVQAAVL PRAEARLLAL HNVSFMELLS AHRRDRQGGL KKYSRYLSLQ TTTLPPAQPA
850 860 870 880
FNLQALGTYF EGLLEGPALA RAEGVSTPLA GRGLAERASQ QS
Isoforms
- Isoform PML-2 of Protein PML - Isoform PML-3 of Protein PML - Isoform PML-4 of Protein PML - Isoform PML-5 of Protein PML - Isoform PML-6 of Protein PML - Isoform PML-7 of Protein PML - Isoform PML-8 of Protein PML - Isoform PML-11 of Protein PML - Isoform PML-12 of Protein PML - Isoform PML-13 of Protein PML - Isoform PML-14 of Protein PML - Isoform PML-8 of Protein PMLSequence View
10 20 30 40 50 60
MEPAPARSPR PQQDPARPQE PTMPPPETPS EGRQPSPSPS PTERAPASEE EFQFLRCQQC
70 80 90 100 110 120
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR
130 140 150 160 170 180
QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG
190 200 210 220 230 240
TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEEL
250 260 270 280 290 300
DAMTQALQEQ DSAFGAVHAQ MHAAVGQLGR ARAETEELIR ERVRQVVAHV RAQERELLEA
310 320 330 340 350 360
VDARYQRDYE EMASRLGRLD AVLQRIRTGS ALVQRMKCYA SDQEVLDMHG FLRQALCRLR
370 380 390 400 410 420
QEEPQSLQAA VRTDGFDEFK VRLQDLSSCI TQGKDAAVSK KASPEAASTP RDPIDVDLPE
430 440 450 460 470 480
EAERVKAQVQ ALGLAEAQPM AVVQSVPGAH PVPVYAFSIK GPSYGEDVSN TTTAQKRKCS
490 500 510 520 530 540
QTQCPRKVIK MESEEGKEAR LARSSPEQPR PSTSKAVSPP HLDGPPSPRS PVIGSEVFLP
550 560 570 580 590 600
NSNHVASGAG EAEERVVVIS SSEDSDAENS SSRELDDSSS ESSDLQLEGP STLRVLDENL
610 620 630 640 650 660
ADPQAEDRPL VFFDLKIDNE TQKISQLAAV NRESKFRVVI QPEAFFSIYS KAVSLEVGLQ
670 680 690 700 710 720
HFLSFLSSMR RPILACYKLW GPGLPNFFRA LEDINRLWEF QEAISGFLAA LPLIRERVPG
730 740 750 760 770 780
ASSFKLKNLA QTYLARNMSE RSAMAAVLAM RDLCRLLEVS PGPQLAQHVY PFSSLQCFAS
790 800 810 820 830 840
LQPLVQAAVL PRAEARLLAL HNVSFMELLS AHRRDRQGGL KKYSRYLSLQ TTTLPPAQPA
850 860 870 880
FNLQALGTYF EGLLEGPALA RAEGVSTPLA GRGLAERASQ QS
10 20 30 40 50 60
MEPAPARSPR PQQDPARPQE PTMPPPETPS EGRQPSPSPS PTERAPASEE EFQFLRCQQC
70 80 90 100 110 120
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR
130 140 150 160 170 180
QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG
190 200 210 220 230 240
TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEEL
250 260 270 280 290 300
DAMTQALQEQ DSAFGAVHAQ MHAAVGQLGR ARAETEELIR ERVRQVVAHV RAQERELLEA
310 320 330 340 350 360
VDARYQRDYE EMASRLGRLD AVLQRIRTGS ALVQRMKCYA SDQEVLDMHG FLRQALCRLR
370 380 390 400 410 420
QEEPQSLQAA VRTDGFDEFK VRLQDLSSCI TQGKDAAVSK KASPEAASTP RDPIDVDLPE
430 440 450 460 470 480
EAERVKAQVQ ALGLAEAQPM AVVQSVPGAH PVPVYAFSIK GPSYGEDVSN TTTAQKRKCS
490 500 510 520 530 540
QTQCPRKVIK MESEEGKEAR LARSSPEQPR PSTSKAVSPP HLDGPPSPRS PVIGSEVFLP
550 560 570 580 590 600
NSNHVASGAG EAEERVVVIS SSEDSDAENS SSRELDDSSS ESSDLQLEGP STLRVLDENL
610 620 630 640 650 660
ADPQAEDRPL VFFDLKIDNE TQKISQLAAV NRESKFRVVI QPEAFFSIYS KAVSLEVGLQ
670 680 690 700 710 720
HFLSFLSSMR RPILACYKLW GPGLPNFFRA LEDINRLWEF QEAISGFLAA LPLIRERVPG
730 740 750 760 770 780
ASSFKLKNLA QTYLARNMSE RSAMAAVLAM RDLCRLLEVS PGPQLAQHVY PFSSLQCFAS
790 800 810 820 830 840
LQPLVQAAVL PRAEARLLAL HNVSFMELLS AHRRDRQGGL KKYSRYLSLQ TTTLPPAQPA
850 860 870 880
FNLQALGTYF EGLLEGPALA RAEGVSTPLA GRGLAERASQ QS
10 20 30 40 50 60
MEPAPARSPR PQQDPARPQE PTMPPPETPS EGRQPSPSPS PTERAPASEE EFQFLRCQQC
70 80 90 100 110 120
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR
130 140 150 160 170 180
QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG
190 200 210 220 230 240
TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEEL
250 260 270 280 290 300
DAMTQALQEQ DSAFGAVHAQ MHAAVGQLGR ARAETEELIR ERVRQVVAHV RAQERELLEA
310 320 330 340 350 360
VDARYQRDYE EMASRLGRLD AVLQRIRTGS ALVQRMKCYA SDQEVLDMHG FLRQALCRLR
370 380 390 400 410 420
QEEPQSLQAA VRTDGFDEFK VRLQDLSSCI TQGKDAAVSK KASPEAASTP RDPIDVDLPE
430 440 450 460 470 480
EAERVKAQVQ ALGLAEAQPM AVVQSVPGAH PVPVYAFSIK GPSYGEDVSN TTTAQKRKCS
490 500 510 520 530 540
QTQCPRKVIK MESEEGKEAR LARSSPEQPR PSTSKAVSPP HLDGPPSPRS PVIGSEVFLP
550 560 570 580 590 600
NSNHVASGAG EAEERVVVIS SSEDSDAENS SSRELDDSSS ESSDLQLEGP STLRVLDENL
610 620 630 640 650 660
ADPQAEDRPL VFFDLKIDNE TQKISQLAAV NRESKFRVVI QPEAFFSIYS KAVSLEVGLQ
670 680 690 700 710 720
HFLSFLSSMR RPILACYKLW GPGLPNFFRA LEDINRLWEF QEAISGFLAA LPLIRERVPG
730 740 750 760 770 780
ASSFKLKNLA QTYLARNMSE RSAMAAVLAM RDLCRLLEVS PGPQLAQHVY PFSSLQCFAS
790 800 810 820 830 840
LQPLVQAAVL PRAEARLLAL HNVSFMELLS AHRRDRQGGL KKYSRYLSLQ TTTLPPAQPA
850 860 870 880
FNLQALGTYF EGLLEGPALA RAEGVSTPLA GRGLAERASQ QS
10 20 30 40 50 60
MEPAPARSPR PQQDPARPQE PTMPPPETPS EGRQPSPSPS PTERAPASEE EFQFLRCQQC
70 80 90 100 110 120
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR
130 140 150 160 170 180
QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG
190 200 210 220 230 240
TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEEL
250 260 270 280 290 300
DAMTQALQEQ DSAFGAVHAQ MHAAVGQLGR ARAETEELIR ERVRQVVAHV RAQERELLEA
310 320 330 340 350 360
VDARYQRDYE EMASRLGRLD AVLQRIRTGS ALVQRMKCYA SDQEVLDMHG FLRQALCRLR
370 380 390 400 410 420
QEEPQSLQAA VRTDGFDEFK VRLQDLSSCI TQGKDAAVSK KASPEAASTP RDPIDVDLPE
430 440 450 460 470 480
EAERVKAQVQ ALGLAEAQPM AVVQSVPGAH PVPVYAFSIK GPSYGEDVSN TTTAQKRKCS
490 500 510 520 530 540
QTQCPRKVIK MESEEGKEAR LARSSPEQPR PSTSKAVSPP HLDGPPSPRS PVIGSEVFLP
550 560 570 580 590 600
NSNHVASGAG EAEERVVVIS SSEDSDAENS SSRELDDSSS ESSDLQLEGP STLRVLDENL
610 620 630 640 650 660
ADPQAEDRPL VFFDLKIDNE TQKISQLAAV NRESKFRVVI QPEAFFSIYS KAVSLEVGLQ
670 680 690 700 710 720
HFLSFLSSMR RPILACYKLW GPGLPNFFRA LEDINRLWEF QEAISGFLAA LPLIRERVPG
730 740 750 760 770 780
ASSFKLKNLA QTYLARNMSE RSAMAAVLAM RDLCRLLEVS PGPQLAQHVY PFSSLQCFAS
790 800 810 820 830 840
LQPLVQAAVL PRAEARLLAL HNVSFMELLS AHRRDRQGGL KKYSRYLSLQ TTTLPPAQPA
850 860 870 880
FNLQALGTYF EGLLEGPALA RAEGVSTPLA GRGLAERASQ QS
10 20 30 40 50 60
MEPAPARSPR PQQDPARPQE PTMPPPETPS EGRQPSPSPS PTERAPASEE EFQFLRCQQC
70 80 90 100 110 120
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR
130 140 150 160 170 180
QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG
190 200 210 220 230 240
TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEEL
250 260 270 280 290 300
DAMTQALQEQ DSAFGAVHAQ MHAAVGQLGR ARAETEELIR ERVRQVVAHV RAQERELLEA
310 320 330 340 350 360
VDARYQRDYE EMASRLGRLD AVLQRIRTGS ALVQRMKCYA SDQEVLDMHG FLRQALCRLR
370 380 390 400 410 420
QEEPQSLQAA VRTDGFDEFK VRLQDLSSCI TQGKDAAVSK KASPEAASTP RDPIDVDLPE
430 440 450 460 470 480
EAERVKAQVQ ALGLAEAQPM AVVQSVPGAH PVPVYAFSIK GPSYGEDVSN TTTAQKRKCS
490 500 510 520 530 540
QTQCPRKVIK MESEEGKEAR LARSSPEQPR PSTSKAVSPP HLDGPPSPRS PVIGSEVFLP
550 560 570 580 590 600
NSNHVASGAG EAEERVVVIS SSEDSDAENS SSRELDDSSS ESSDLQLEGP STLRVLDENL
610 620 630 640 650 660
ADPQAEDRPL VFFDLKIDNE TQKISQLAAV NRESKFRVVI QPEAFFSIYS KAVSLEVGLQ
670 680 690 700 710 720
HFLSFLSSMR RPILACYKLW GPGLPNFFRA LEDINRLWEF QEAISGFLAA LPLIRERVPG
730 740 750 760 770 780
ASSFKLKNLA QTYLARNMSE RSAMAAVLAM RDLCRLLEVS PGPQLAQHVY PFSSLQCFAS
790 800 810 820 830 840
LQPLVQAAVL PRAEARLLAL HNVSFMELLS AHRRDRQGGL KKYSRYLSLQ TTTLPPAQPA
850 860 870 880
FNLQALGTYF EGLLEGPALA RAEGVSTPLA GRGLAERASQ QS
10 20 30 40 50 60
MEPAPARSPR PQQDPARPQE PTMPPPETPS EGRQPSPSPS PTERAPASEE EFQFLRCQQC
70 80 90 100 110 120
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR
130 140 150 160 170 180
QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG
190 200 210 220 230 240
TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEEL
250 260 270 280 290 300
DAMTQALQEQ DSAFGAVHAQ MHAAVGQLGR ARAETEELIR ERVRQVVAHV RAQERELLEA
310 320 330 340 350 360
VDARYQRDYE EMASRLGRLD AVLQRIRTGS ALVQRMKCYA SDQEVLDMHG FLRQALCRLR
370 380 390 400 410 420
QEEPQSLQAA VRTDGFDEFK VRLQDLSSCI TQGKDAAVSK KASPEAASTP RDPIDVDLPE
430 440 450 460 470 480
EAERVKAQVQ ALGLAEAQPM AVVQSVPGAH PVPVYAFSIK GPSYGEDVSN TTTAQKRKCS
490 500 510 520 530 540
QTQCPRKVIK MESEEGKEAR LARSSPEQPR PSTSKAVSPP HLDGPPSPRS PVIGSEVFLP
550 560 570 580 590 600
NSNHVASGAG EAEERVVVIS SSEDSDAENS SSRELDDSSS ESSDLQLEGP STLRVLDENL
610 620 630 640 650 660
ADPQAEDRPL VFFDLKIDNE TQKISQLAAV NRESKFRVVI QPEAFFSIYS KAVSLEVGLQ
670 680 690 700 710 720
HFLSFLSSMR RPILACYKLW GPGLPNFFRA LEDINRLWEF QEAISGFLAA LPLIRERVPG
730 740 750 760 770 780
ASSFKLKNLA QTYLARNMSE RSAMAAVLAM RDLCRLLEVS PGPQLAQHVY PFSSLQCFAS
790 800 810 820 830 840
LQPLVQAAVL PRAEARLLAL HNVSFMELLS AHRRDRQGGL KKYSRYLSLQ TTTLPPAQPA
850 860 870 880
FNLQALGTYF EGLLEGPALA RAEGVSTPLA GRGLAERASQ QS
10 20 30 40 50 60
MEPAPARSPR PQQDPARPQE PTMPPPETPS EGRQPSPSPS PTERAPASEE EFQFLRCQQC
70 80 90 100 110 120
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR
130 140 150 160 170 180
QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG
190 200 210 220 230 240
TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEEL
250 260 270 280 290 300
DAMTQALQEQ DSAFGAVHAQ MHAAVGQLGR ARAETEELIR ERVRQVVAHV RAQERELLEA
310 320 330 340 350 360
VDARYQRDYE EMASRLGRLD AVLQRIRTGS ALVQRMKCYA SDQEVLDMHG FLRQALCRLR
370 380 390 400 410 420
QEEPQSLQAA VRTDGFDEFK VRLQDLSSCI TQGKDAAVSK KASPEAASTP RDPIDVDLPE
430 440 450 460 470 480
EAERVKAQVQ ALGLAEAQPM AVVQSVPGAH PVPVYAFSIK GPSYGEDVSN TTTAQKRKCS
490 500 510 520 530 540
QTQCPRKVIK MESEEGKEAR LARSSPEQPR PSTSKAVSPP HLDGPPSPRS PVIGSEVFLP
550 560 570 580 590 600
NSNHVASGAG EAEERVVVIS SSEDSDAENS SSRELDDSSS ESSDLQLEGP STLRVLDENL
610 620 630 640 650 660
ADPQAEDRPL VFFDLKIDNE TQKISQLAAV NRESKFRVVI QPEAFFSIYS KAVSLEVGLQ
670 680 690 700 710 720
HFLSFLSSMR RPILACYKLW GPGLPNFFRA LEDINRLWEF QEAISGFLAA LPLIRERVPG
730 740 750 760 770 780
ASSFKLKNLA QTYLARNMSE RSAMAAVLAM RDLCRLLEVS PGPQLAQHVY PFSSLQCFAS
790 800 810 820 830 840
LQPLVQAAVL PRAEARLLAL HNVSFMELLS AHRRDRQGGL KKYSRYLSLQ TTTLPPAQPA
850 860 870 880
FNLQALGTYF EGLLEGPALA RAEGVSTPLA GRGLAERASQ QS
10 20 30 40 50 60
MEPAPARSPR PQQDPARPQE PTMPPPETPS EGRQPSPSPS PTERAPASEE EFQFLRCQQC
70 80 90 100 110 120
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR
130 140 150 160 170 180
QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG
190 200 210 220 230 240
TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEEL
250 260 270 280 290 300
DAMTQALQEQ DSAFGAVHAQ MHAAVGQLGR ARAETEELIR ERVRQVVAHV RAQERELLEA
310 320 330 340 350 360
VDARYQRDYE EMASRLGRLD AVLQRIRTGS ALVQRMKCYA SDQEVLDMHG FLRQALCRLR
370 380 390 400 410 420
QEEPQSLQAA VRTDGFDEFK VRLQDLSSCI TQGKDAAVSK KASPEAASTP RDPIDVDLPE
430 440 450 460 470 480
EAERVKAQVQ ALGLAEAQPM AVVQSVPGAH PVPVYAFSIK GPSYGEDVSN TTTAQKRKCS
490 500 510 520 530 540
QTQCPRKVIK MESEEGKEAR LARSSPEQPR PSTSKAVSPP HLDGPPSPRS PVIGSEVFLP
550 560 570 580 590 600
NSNHVASGAG EAEERVVVIS SSEDSDAENS SSRELDDSSS ESSDLQLEGP STLRVLDENL
610 620 630 640 650 660
ADPQAEDRPL VFFDLKIDNE TQKISQLAAV NRESKFRVVI QPEAFFSIYS KAVSLEVGLQ
670 680 690 700 710 720
HFLSFLSSMR RPILACYKLW GPGLPNFFRA LEDINRLWEF QEAISGFLAA LPLIRERVPG
730 740 750 760 770 780
ASSFKLKNLA QTYLARNMSE RSAMAAVLAM RDLCRLLEVS PGPQLAQHVY PFSSLQCFAS
790 800 810 820 830 840
LQPLVQAAVL PRAEARLLAL HNVSFMELLS AHRRDRQGGL KKYSRYLSLQ TTTLPPAQPA
850 860 870 880
FNLQALGTYF EGLLEGPALA RAEGVSTPLA GRGLAERASQ QS
10 20 30 40 50 60
MEPAPARSPR PQQDPARPQE PTMPPPETPS EGRQPSPSPS PTERAPASEE EFQFLRCQQC
70 80 90 100 110 120
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR
130 140 150 160 170 180
QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG
190 200 210 220 230 240
TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEEL
250 260 270 280 290 300
DAMTQALQEQ DSAFGAVHAQ MHAAVGQLGR ARAETEELIR ERVRQVVAHV RAQERELLEA
310 320 330 340 350 360
VDARYQRDYE EMASRLGRLD AVLQRIRTGS ALVQRMKCYA SDQEVLDMHG FLRQALCRLR
370 380 390 400 410 420
QEEPQSLQAA VRTDGFDEFK VRLQDLSSCI TQGKDAAVSK KASPEAASTP RDPIDVDLPE
430 440 450 460 470 480
EAERVKAQVQ ALGLAEAQPM AVVQSVPGAH PVPVYAFSIK GPSYGEDVSN TTTAQKRKCS
490 500 510 520 530 540
QTQCPRKVIK MESEEGKEAR LARSSPEQPR PSTSKAVSPP HLDGPPSPRS PVIGSEVFLP
550 560 570 580 590 600
NSNHVASGAG EAEERVVVIS SSEDSDAENS SSRELDDSSS ESSDLQLEGP STLRVLDENL
610 620 630 640 650 660
ADPQAEDRPL VFFDLKIDNE TQKISQLAAV NRESKFRVVI QPEAFFSIYS KAVSLEVGLQ
670 680 690 700 710 720
HFLSFLSSMR RPILACYKLW GPGLPNFFRA LEDINRLWEF QEAISGFLAA LPLIRERVPG
730 740 750 760 770 780
ASSFKLKNLA QTYLARNMSE RSAMAAVLAM RDLCRLLEVS PGPQLAQHVY PFSSLQCFAS
790 800 810 820 830 840
LQPLVQAAVL PRAEARLLAL HNVSFMELLS AHRRDRQGGL KKYSRYLSLQ TTTLPPAQPA
850 860 870 880
FNLQALGTYF EGLLEGPALA RAEGVSTPLA GRGLAERASQ QS
10 20 30 40 50 60
MEPAPARSPR PQQDPARPQE PTMPPPETPS EGRQPSPSPS PTERAPASEE EFQFLRCQQC
70 80 90 100 110 120
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR
130 140 150 160 170 180
QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG
190 200 210 220 230 240
TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEEL
250 260 270 280 290 300
DAMTQALQEQ DSAFGAVHAQ MHAAVGQLGR ARAETEELIR ERVRQVVAHV RAQERELLEA
310 320 330 340 350 360
VDARYQRDYE EMASRLGRLD AVLQRIRTGS ALVQRMKCYA SDQEVLDMHG FLRQALCRLR
370 380 390 400 410 420
QEEPQSLQAA VRTDGFDEFK VRLQDLSSCI TQGKDAAVSK KASPEAASTP RDPIDVDLPE
430 440 450 460 470 480
EAERVKAQVQ ALGLAEAQPM AVVQSVPGAH PVPVYAFSIK GPSYGEDVSN TTTAQKRKCS
490 500 510 520 530 540
QTQCPRKVIK MESEEGKEAR LARSSPEQPR PSTSKAVSPP HLDGPPSPRS PVIGSEVFLP
550 560 570 580 590 600
NSNHVASGAG EAEERVVVIS SSEDSDAENS SSRELDDSSS ESSDLQLEGP STLRVLDENL
610 620 630 640 650 660
ADPQAEDRPL VFFDLKIDNE TQKISQLAAV NRESKFRVVI QPEAFFSIYS KAVSLEVGLQ
670 680 690 700 710 720
HFLSFLSSMR RPILACYKLW GPGLPNFFRA LEDINRLWEF QEAISGFLAA LPLIRERVPG
730 740 750 760 770 780
ASSFKLKNLA QTYLARNMSE RSAMAAVLAM RDLCRLLEVS PGPQLAQHVY PFSSLQCFAS
790 800 810 820 830 840
LQPLVQAAVL PRAEARLLAL HNVSFMELLS AHRRDRQGGL KKYSRYLSLQ TTTLPPAQPA
850 860 870 880
FNLQALGTYF EGLLEGPALA RAEGVSTPLA GRGLAERASQ QS
10 20 30 40 50 60
MEPAPARSPR PQQDPARPQE PTMPPPETPS EGRQPSPSPS PTERAPASEE EFQFLRCQQC
70 80 90 100 110 120
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR
130 140 150 160 170 180
QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG
190 200 210 220 230 240
TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEEL
250 260 270 280 290 300
DAMTQALQEQ DSAFGAVHAQ MHAAVGQLGR ARAETEELIR ERVRQVVAHV RAQERELLEA
310 320 330 340 350 360
VDARYQRDYE EMASRLGRLD AVLQRIRTGS ALVQRMKCYA SDQEVLDMHG FLRQALCRLR
370 380 390 400 410 420
QEEPQSLQAA VRTDGFDEFK VRLQDLSSCI TQGKDAAVSK KASPEAASTP RDPIDVDLPE
430 440 450 460 470 480
EAERVKAQVQ ALGLAEAQPM AVVQSVPGAH PVPVYAFSIK GPSYGEDVSN TTTAQKRKCS
490 500 510 520 530 540
QTQCPRKVIK MESEEGKEAR LARSSPEQPR PSTSKAVSPP HLDGPPSPRS PVIGSEVFLP
550 560 570 580 590 600
NSNHVASGAG EAEERVVVIS SSEDSDAENS SSRELDDSSS ESSDLQLEGP STLRVLDENL
610 620 630 640 650 660
ADPQAEDRPL VFFDLKIDNE TQKISQLAAV NRESKFRVVI QPEAFFSIYS KAVSLEVGLQ
670 680 690 700 710 720
HFLSFLSSMR RPILACYKLW GPGLPNFFRA LEDINRLWEF QEAISGFLAA LPLIRERVPG
730 740 750 760 770 780
ASSFKLKNLA QTYLARNMSE RSAMAAVLAM RDLCRLLEVS PGPQLAQHVY PFSSLQCFAS
790 800 810 820 830 840
LQPLVQAAVL PRAEARLLAL HNVSFMELLS AHRRDRQGGL KKYSRYLSLQ TTTLPPAQPA
850 860 870 880
FNLQALGTYF EGLLEGPALA RAEGVSTPLA GRGLAERASQ QS
10 20 30 40 50 60
MEPAPARSPR PQQDPARPQE PTMPPPETPS EGRQPSPSPS PTERAPASEE EFQFLRCQQC
70 80 90 100 110 120
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR
130 140 150 160 170 180
QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG
190 200 210 220 230 240
TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEEL
250 260 270 280 290 300
DAMTQALQEQ DSAFGAVHAQ MHAAVGQLGR ARAETEELIR ERVRQVVAHV RAQERELLEA
310 320 330 340 350 360
VDARYQRDYE EMASRLGRLD AVLQRIRTGS ALVQRMKCYA SDQEVLDMHG FLRQALCRLR
370 380 390 400 410 420
QEEPQSLQAA VRTDGFDEFK VRLQDLSSCI TQGKDAAVSK KASPEAASTP RDPIDVDLPE
430 440 450 460 470 480
EAERVKAQVQ ALGLAEAQPM AVVQSVPGAH PVPVYAFSIK GPSYGEDVSN TTTAQKRKCS
490 500 510 520 530 540
QTQCPRKVIK MESEEGKEAR LARSSPEQPR PSTSKAVSPP HLDGPPSPRS PVIGSEVFLP
550 560 570 580 590 600
NSNHVASGAG EAEERVVVIS SSEDSDAENS SSRELDDSSS ESSDLQLEGP STLRVLDENL
610 620 630 640 650 660
ADPQAEDRPL VFFDLKIDNE TQKISQLAAV NRESKFRVVI QPEAFFSIYS KAVSLEVGLQ
670 680 690 700 710 720
HFLSFLSSMR RPILACYKLW GPGLPNFFRA LEDINRLWEF QEAISGFLAA LPLIRERVPG
730 740 750 760 770 780
ASSFKLKNLA QTYLARNMSE RSAMAAVLAM RDLCRLLEVS PGPQLAQHVY PFSSLQCFAS
790 800 810 820 830 840
LQPLVQAAVL PRAEARLLAL HNVSFMELLS AHRRDRQGGL KKYSRYLSLQ TTTLPPAQPA
850 860 870 880
FNLQALGTYF EGLLEGPALA RAEGVSTPLA GRGLAERASQ QS
Protein Neighborhood
Domains & Features
12 N-termini - 6 C-termini - 6 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P29590-1-unknown | MEPAPA... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P29590-1-unknown | MEPAPA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85661 | |||
P29590-1-unknown | MEPAPA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85662 | |||
P29590-1-unknown | MEPAPA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85663 | |||
P29590-1-unknown | MEPAPA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85664 | |||
P29590-1-unknown | MEPAPA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85665 | |||
P29590-1-unknown | MEPAPA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85667 | |||
P29590-408- | STPRDP... | 408 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P29590-408-unknown | STPRDP... | 408 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176948 | |||
P29590-408-unknown | STPRDP... | 408 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176949 | |||
P29590-408-unknown | STPRDP... | 408 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176950 | |||
P29590-408-unknown | STPRDP... | 408 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176951 | |||
P29590-408-unknown | STPRDP... | 408 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176952 | |||
P29590-408-unknown | STPRDP... | 408 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176953 | |||
P29590-443-unknown | VQSVPG... | 443 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9401 | |||
P29590-443-unknown | VQSVPG... | 443 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152684 | |||
P29590-443-unknown | VQSVPG... | 443 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152685 | |||
P29590-443-unknown | VQSVPG... | 443 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152686 | |||
P29590-443-unknown | VQSVPG... | 443 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152687 | |||
P29590-443-unknown | VQSVPG... | 443 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152688 | |||
P29590-443-unknown | VQSVPG... | 443 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152689 | |||
P29590-445-unknown | SVPGAH... | 445 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164966 | |||
P29590-445-unknown | SVPGAH... | 445 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164967 | |||
P29590-445-unknown | SVPGAH... | 445 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164968 | |||
P29590-445-unknown | SVPGAH... | 445 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164969 | |||
P29590-445-unknown | SVPGAH... | 445 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164970 | |||
P29590-445-unknown | SVPGAH... | 445 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164971 | |||
P29590-445- | SVPGAH... | 445 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
P29590-445- | SVPGAH... | 445 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P29590-455-unknown | YAFSIK... | 455 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9408 | |||
P29590-455-unknown | YAFSIK... | 455 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152846 | |||
P29590-455-unknown | YAFSIK... | 455 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152847 | |||
P29590-455-unknown | YAFSIK... | 455 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152848 | |||
P29590-455-unknown | YAFSIK... | 455 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152850 | |||
P29590-455-unknown | YAFSIK... | 455 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152851 | |||
P29590-455-unknown | YAFSIK... | 455 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152852 | |||
P29590-466-unknown | EDVSNT... | 466 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19002 | |||
P29590-466-unknown | EDVSNT... | 466 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17545 | |||
P29590-466-unknown | EDVSNT... | 466 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153007 | |||
P29590-466-unknown | EDVSNT... | 466 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153008 | |||
P29590-466-unknown | EDVSNT... | 466 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153009 | |||
P29590-466-unknown | EDVSNT... | 466 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153010 | |||
P29590-466-unknown | EDVSNT... | 466 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153011 | |||
P29590-466-unknown | EDVSNT... | 466 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153012 | |||
P29590-495-unknown | EGKEAR... | 495 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11418 | |||
P29590-495-unknown | EGKEAR... | 495 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153359 | |||
P29590-495-unknown | EGKEAR... | 495 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153360 | |||
P29590-495-unknown | EGKEAR... | 495 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153361 | |||
P29590-495-unknown | EGKEAR... | 495 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153362 | |||
P29590-495-unknown | EGKEAR... | 495 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153363 | |||
P29590-495-unknown | EGKEAR... | 495 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153364 | |||
P29590-524-unknown | GPPSPR... | 524 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1766 | |||
P29590-524-unknown | GPPSPR... | 524 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153670 | |||
P29590-524-unknown | GPPSPR... | 524 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153671 | |||
P29590-524-unknown | GPPSPR... | 524 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153672 | |||
P29590-524-unknown | GPPSPR... | 524 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153673 | |||
P29590-524-unknown | GPPSPR... | 524 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153674 | |||
P29590-524-unknown | GPPSPR... | 524 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153675 | |||
P29590-544- | HVASGA... | 544 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P29590-544-unknown | HVASGA... | 544 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174448 | |||
P29590-544-unknown | HVASGA... | 544 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174449 | |||
P29590-544-unknown | HVASGA... | 544 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174450 | |||
P29590-544-unknown | HVASGA... | 544 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174451 | |||
P29590-544-unknown | HVASGA... | 544 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174452 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...QPMAVV | 442 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9401 | |||
...QPMAVV | 442 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136103 | |||
...QPMAVV | 442 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136104 | |||
...QPMAVV | 442 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136105 | |||
...QPMAVV | 442 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136106 | |||
...QPMAVV | 442 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136107 | |||
...QPMAVV | 442 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136108 | |||
...HPVPVY | 454 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9408 | |||
...HPVPVY | 454 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136271 | |||
...HPVPVY | 454 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136272 | |||
...HPVPVY | 454 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136273 | |||
...HPVPVY | 454 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136275 | |||
...HPVPVY | 454 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136276 | |||
...HPVPVY | 454 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136277 | |||
...GPSYGE | 465 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19002 | |||
...GPSYGE | 465 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17545 | |||
...GPSYGE | 465 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136433 | |||
...GPSYGE | 465 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136434 | |||
...GPSYGE | 465 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136435 | |||
...GPSYGE | 465 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136436 | |||
...GPSYGE | 465 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136437 | |||
...GPSYGE | 465 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136438 | |||
...KMESEE | 494 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11418 | |||
...KMESEE | 494 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136783 | |||
...KMESEE | 494 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136784 | |||
...KMESEE | 494 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136785 | |||
...KMESEE | 494 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136786 | |||
...KMESEE | 494 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136787 | |||
...KMESEE | 494 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136788 | |||
...PPHLDG | 523 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1766 | |||
...PPHLDG | 523 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt137093 | |||
...PPHLDG | 523 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt137094 | |||
...PPHLDG | 523 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt137095 | |||
...PPHLDG | 523 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt137096 | |||
...PPHLDG | 523 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt137097 | |||
...PPHLDG | 523 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt137098 | |||
...ASQQS | 882 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|