P24592: Insulin-like growth factor-binding protein 6
| Protein names | - Insulin-like growth factor-binding protein 6 - IBP-6 - IGF-binding protein 6 - IGFBP-6 |
|---|---|
| Gene names | IGFBP6 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P24592 |
2
N-termini
2
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MTPHRLLPPL LLLLALLLAA SPGGALARCP GCGQGVQAGC PGGCVEEEDG GSPAEGCAEA
70 80 90 100 110 120
EGCLRREGQE CGVYTPNCAP GLQCHPPKDD EAPLRALLLG RGRCLPARAP AVAEENPKES
130 140 150 160 170 180
KPQAGTARPQ DVNRRDQQRN PGTSTTPSQP NSAGVQDTEM GPCRRHLDSV LQQLQTEVYR
190 200 210 220 230 240
GAQTLYVPNC DHRGFYRKRQ CRSSQGQRRG PCWCVDRMGK SLPGSPDGNG SSSCPTGSSG
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P24592-28-unknown | RCPGCG... | 28 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P24592-181-unknown | GAQTLY... | 181 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18950 | |||
| P24592-181-unknown | GAQTLY... | 181 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17529 | |||
| P24592-181-unknown | GAQTLY... | 181 | unknown | Wildes D. et al: Sampling the N-terminal proteome of human blood | 20173099 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...TEVYRG | 180 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18950 | |||
| ...TEVYRG | 180 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17529 | |||
| ...TGSSG | 240 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| MEP1B_HUMAN | 180 | VYRG.|.GAQT | inferred from experiment | unknown | MEROPS | Overall CM | Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) | 21693781, |
| MEP1A_HUMAN | 180 | VYRG.|.GAQT | inferred from experiment | unknown | MEROPS | Overall CM | Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) | 21693781, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|