P50395: Rab GDP dissociation inhibitor beta

General Information

Protein names	- Rab GDP dissociation inhibitor beta - Rab GDI beta - Guanosine diphosphate dissociation inhibitor 2 - GDI-2
Gene names	GDI2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P50395

10 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNEEYDVIVL GTGLTECILS GIMSVNGKKV LHMDRNPYYG GESASITPLE DLYKRFKIPG
        70         80         90        100        110        120
SPPESMGRGR DWNVDLIPKF LMANGQLVKM LLYTEVTRYL DFKVTEGSFV YKGGKIYKVP
       130        140        150        160        170        180
STEAEALASS LMGLFEKRRF RKFLVYVANF DEKDPRTFEG IDPKKTTMRD VYKKFDLGQD
       190        200        210        220        230        240
VIDFTGHALA LYRTDDYLDQ PCYETINRIK LYSESLARYG KSPYLYPLYG LGELPQGFAR
       250        260        270        280        290        300
LSAIYGGTYM LNKPIEEIIV QNGKVIGVKS EGEIARCKQL ICDPSYVKDR VEKVGQVIRV
       310        320        330        340        350        360
ICILSHPIKN TNDANSCQII IPQNQVNRKS DIYVCMISFA HNVAAQGKYI AIVSTTVETK
       370        380        390        400        410        420
EPEKEIRPAL ELLEPIEQKF VSISDLLVPK DLGTESQIFI SRTYDATTHF ETTCDDIKNI
       430        440
YKRMTGSEFD FEEMKRKKND IYGED

Isoforms

- Isoform 2 of Rab GDP dissociation inhibitor beta

Sequence View

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Protein Neighborhood

Domains & Features

10 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
P50395-1-Acetylation	MNEEYD...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P50395-1-Acetylation	MNEEYD...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt97651
P50395-1-unknown	MNEEYD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75837
P50395-43-unknown	SASITP...	43		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182754
P50395-43-	SASITP...	43			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P50395-45-unknown	SITPLE...	45		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182756
P50395-45-	SITPLE...	45			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P50395-194-	TDDYLD...	194			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P50395-194-unknown	TDDYLD...	194		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182750
P50395-253-unknown	KPIEEI...	253		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17683
P50395-253-unknown	KPIEEI...	253		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146818
P50395-257-Pyrrolidone carboxylic acid (Glu)	EIIVQN...	257	pyrrolidone carboxylic acid-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P50395-257-Pyrrolidone carboxylic acid (Glu)	EIIVQN...	257	pyrrolidone carboxylic acid-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182752

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...TYMLNK	252	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17683
...TYMLNK	252	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt130141
...IYGED	445	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...IYGED	445	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt71455
...IYGED	445		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...IYGED	445		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...IYGED	445		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...IYGED	445		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	252	MLNK.\|.KPIE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)