Q9UQ80: Proliferation-associated protein 2G4

General Information

Protein names	- Proliferation-associated protein 2G4 - Cell cycle protein p38-2G4 homolog - hG4-1 - ErbB3-binding protein 1
Gene names	PA2G4
Organism	Homo sapiens
Protease Family
Protease ID	M24.973
Chromosome location
UniProt ID	Q9UQ80

16 N-termini

12 C-termini

15 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSGEDEQQEQ TIAEDLVVTK YKMGGDIANR VLRSLVEASS SGVSVLSLCE KGDAMIMEET
        70         80         90        100        110        120
GKIFKKEKEM KKGIAFPTSI SVNNCVCHFS PLKSDQDYIL KEGDLVKIDL GVHVDGFIAN
       130        140        150        160        170        180
VAHTFVVDVA QGTQVTGRKA DVIKAAHLCA EAALRLVKPG NQNTQVTEAW NKVAHSFNCT
       190        200        210        220        230        240
PIEGMLSHQL KQHVIDGEKT IIQNPTDQQK KDHEKAEFEV HEVYAVDVLV SSGEGKAKDA
       250        260        270        280        290        300
GQRTTIYKRD PSKQYGLKMK TSRAFFSEVE RRFDAMPFTL RAFEDEKKAR MGVVECAKHE
       310        320        330        340        350        360
LLQPFNVLYE KEGEFVAQFK FTVLLMPNGP MRITSGPFEP DLYKSEMEVQ DAELKALLQS
       370        380        390
SASRKTQKKK KKKASKTAEN ATSGETLEEN EAGD

Isoforms

- Isoform 2 of Proliferation-associated protein 2G4

Sequence View

        10         20         30         40         50         60
MSGEDEQQEQ TIAEDLVVTK YKMGGDIANR VLRSLVEASS SGVSVLSLCE KGDAMIMEET
        70         80         90        100        110        120
GKIFKKEKEM KKGIAFPTSI SVNNCVCHFS PLKSDQDYIL KEGDLVKIDL GVHVDGFIAN
       130        140        150        160        170        180
VAHTFVVDVA QGTQVTGRKA DVIKAAHLCA EAALRLVKPG NQNTQVTEAW NKVAHSFNCT
       190        200        210        220        230        240
PIEGMLSHQL KQHVIDGEKT IIQNPTDQQK KDHEKAEFEV HEVYAVDVLV SSGEGKAKDA
       250        260        270        280        290        300
GQRTTIYKRD PSKQYGLKMK TSRAFFSEVE RRFDAMPFTL RAFEDEKKAR MGVVECAKHE
       310        320        330        340        350        360
LLQPFNVLYE KEGEFVAQFK FTVLLMPNGP MRITSGPFEP DLYKSEMEVQ DAELKALLQS
       370        380        390
SASRKTQKKK KKKASKTAEN ATSGETLEEN EAGD

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UQ80-2-unknown	MSGEDE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UQ80-2-Acetylation	SGEDEQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UQ80-2-Acetylation	SGEDEQ...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9UQ80-2-Acetylation	SGEDEQ...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q9UQ80-2-Acetylation	SGEDEQ...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9UQ80-2-Acetylation	SGEDEQ...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q9UQ80-5-unknown	DEQQEQ...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19867
Q9UQ80-9-unknown	EQTIAE...	9		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18177
Q9UQ80-9-unknown	EQTIAE...	9		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19868
Q9UQ80-15-unknown	DLVVTK...	15		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18178
Q9UQ80-15-unknown	DLVVTK...	15		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13585
Q9UQ80-15-unknown	DLVVTK...	15		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19869
Q9UQ80-23-unknown	MGGDIA...	23		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q9UQ80-55-unknown	MIMEET...	55		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000447389
Q9UQ80-124-	TFVVDV...	124			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q9UQ80-131-unknown	QGTQVT...	131		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8153
Q9UQ80-141-unknown	DVIKAA...	141		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18179
Q9UQ80-141-unknown	DVIKAA...	141		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19870
Q9UQ80-180-unknown	TPIEGM...	180		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18180
Q9UQ80-180-unknown	TPIEGM...	180		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19871
Q9UQ80-226-unknown	VDVLVS...	226		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18181
Q9UQ80-226-unknown	VDVLVS...	226		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19872
Q9UQ80-342-unknown	LYKSEM...	342		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13586
Q9UQ80-345-	SEMEVQ...	345			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UQ80-374-	ASKTAE...	374			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9UQ80-386-unknown	TLEENE...	386		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13587

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...EDEQQE	8	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18177
...EDEQQE	8	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19868
...QTIAED	14	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18178
...QTIAED	14	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13585
...QTIAED	14	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19869
...VDGFIA	118	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000447389
...VVDVAQ	130	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8153
...TGRKAD	140	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18179
...TGRKAD	140	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19870
...HSFNCT	179	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18180
...HSFNCT	179	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19871
...VIDGEK	198	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000447615
...HEVYAV	225	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18181
...HEVYAV	225	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19872
...PFEPDL	341	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13586
...ATSGET	385	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13587
...NEAGD	394	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...NEAGD	394		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...NEAGD	394		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...NEAGD	394		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...NEAGD	394		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	4	SGED.\|.DEQQ	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	8	EQQE.\|.EQTI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	8	EQQE.\|.EQTI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	14	IAED.\|.DLVV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAB_HUMAN	14	IAED.\|.DLVV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
MEP1B_HUMAN	14	IAED.\|.DLVV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATS_HUMAN	130	DVAQ.\|.QGTQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	140	RKAD.\|.DVIK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	140	RKAD.\|.DVIK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	179	FNCT.\|.TPIE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	179	FNCT.\|.TPIE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	225	VYAV.\|.VDVL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	225	VYAV.\|.VDVL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAB_HUMAN	341	EPDL.\|.LYKS	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_HUMAN	385	SGET.\|.TLEE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

TopFIND

Q9UQ80: Proliferation-associated protein 2G4

General Information

16

N-termini

12

C-termini

15

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

16 N-termini - 12 C-termini - 15 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates