P22392: Nucleoside diphosphate kinase B
Protein names | - Nucleoside diphosphate kinase B - NDK B - NDP kinase B - 2.7.4.6 {ECO:0000269|PubMed:1851158, ECO:0000269|PubMed:25679041} - C-myc purine-binding transcription factor PUF - Histidine protein kinase NDKB - 2.7.13.3 {ECO:0000269|PubMed:20946858} - nm23-H2 |
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Gene names | NME2 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P22392 |
13
N-termini
10
C-termini
13
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MANLERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVAMKF LRASEEHLKQ HYIDLKDRPF
70 80 90 100 110 120
FPGLVKYMNS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS
130 140 150
DSVKSAEKEI SLWFKPEELV DYKSCAHDWV YE
Isoforms
- Isoform 3 of Nucleoside diphosphate kinase BSequence View
10 20 30 40 50 60
MANLERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVAMKF LRASEEHLKQ HYIDLKDRPF
70 80 90 100 110 120
FPGLVKYMNS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS
130 140 150
DSVKSAEKEI SLWFKPEELV DYKSCAHDWV YE
Protein Neighborhood
Domains & Features
13 N-termini - 10 C-termini - 13 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P22392-2-unknown | MANLER... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P22392-1-unknown | MANLER... | 1 | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | |||
P22392-1-unknown | MANLER... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt100569 | |||
P22392-1-unknown | MANLER... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P22392-2-Acetylation | ANLERT... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
P22392-2-Acetylation | ANLERT... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110618 | ||
P22392-10-unknown | AIKPDG... | 10 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5692 | |||
P22392-10-unknown | AIKPDG... | 10 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7370 | |||
P22392-30-unknown | QKGFRL... | 30 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
P22392-30-unknown | QKGFRL... | 30 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt195592 | |||
P22392-76-unknown | MVWEGL... | 76 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3700 | |||
P22392-76-unknown | MVWEGL... | 76 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt146280 | |||
P22392-77-unknown | VWEGLN... | 77 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3702 | |||
P22392-77-unknown | VWEGLN... | 77 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt146317 | |||
P22392-92-unknown | GETNPA... | 92 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18907 | |||
P22392-93-unknown | ETNPAD... | 93 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5693 | |||
P22392-93-unknown | ETNPAD... | 93 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7371 | |||
P22392-93-unknown | ETNPAD... | 93 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18908 | |||
P22392-114-unknown | RNIIHG... | 114 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7372 | |||
P22392-114-unknown | RNIIHG... | 114 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt147703 | |||
P22392-119-unknown | GSDSVK... | 119 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5694 | |||
P22392-119-unknown | GSDSVK... | 119 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt147870 | |||
P22392-134-unknown | FKPEEL... | 134 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17489 | |||
P22392-134-unknown | FKPEEL... | 134 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt148375 | |||
P22392-135-unknown | KPEELV... | 135 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5696 | |||
P22392-135-unknown | KPEELV... | 135 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17491 | |||
P22392-135-unknown | KPEELV... | 135 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt148399 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...ERTFIA | 9 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5692 | |||
...ERTFIA | 9 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7370 | |||
...GPVVAM | 75 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3700 | |||
...GPVVAM | 75 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt129585 | |||
...PVVAMV | 76 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3702 | |||
...PVVAMV | 76 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt129620 | |||
...GRVMLG | 91 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18907 | |||
...RVMLGE | 92 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5693 | |||
...RVMLGE | 92 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7371 | |||
...RVMLGE | 92 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18908 | |||
...CIQVGR | 113 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7372 | |||
...CIQVGR | 113 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt131057 | |||
...RNIIHG | 118 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5694 | |||
...RNIIHG | 118 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt131226 | |||
...EISLWF | 133 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17489 | |||
...EISLWF | 133 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt131747 | |||
...ISLWFK | 134 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5696 | |||
...ISLWFK | 134 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17491 | |||
...ISLWFK | 134 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt131772 | |||
...DWVYE | 152 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...DWVYE | 152 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt78088 |
Cleavages
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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