Q9BQ61: Telomerase RNA component interacting RNase {ECO:0000303|PubMed:28322335, ECO:0000312|HGNC:HGNC:28424}
| Protein names | - Telomerase RNA component interacting RNase {ECO:0000303|PubMed:28322335, ECO:0000312|HGNC:HGNC:28424} - 3.1.13.- {ECO:0000269|PubMed:28322335} - Exoribonuclease TRIR {ECO:0000305} |
|---|---|
| Gene names | C19orf43 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q9BQ61 |
2
N-termini
2
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAARGRRAEP QGREAPGPAG GGGGGSRWAE SGSGTSPESG DEEVSGAGSS PVSGGVNLFA
70 80 90 100 110 120
NDGSFLELFK RKMEEEQRQR QEEPPPGPQR PDQSAAAAGP GDPKRKGGPG STLSFVGKRR
130 140 150 160 170
GGNKLALKTG IVAKKQKTED EVLTSKGDAW AKYMAEVKKY KAHQCGDDDK TRPLVK
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q9BQ61-1-unknown | MAARGR... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q9BQ61-62-unknown | DGSFLE... | 62 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19760 | |||
| Q9BQ61-62-unknown | DGSFLE... | 62 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18095 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...NLFAND | 61 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19760 | |||
| ...NLFAND | 61 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18095 | |||
| ...RPLVK | 176 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| MEP1B_HUMAN | 61 | FAND.|.DGSF | inferred from experiment | unknown | MEROPS | Overall CM | Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) | 21693781, |
| MEP1A_HUMAN | 61 | FAND.|.DGSF | inferred from experiment | unknown | MEROPS | Overall CM | Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) | 21693781, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|