P19013: Keratin, type II cytoskeletal 4
| Protein names | - Keratin, type II cytoskeletal 4 - Cytokeratin-4 - CK-4 - Keratin-4 - K4 - Type-II keratin Kb4 |
|---|---|
| Gene names | KRT4 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P19013 |
2
N-termini
2
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MIARQQCVRG GPRGFSCGSA IVGGGKRGAF SSVSMSGGAG RCSSGGFGSR SLYNLRGNKS
70 80 90 100 110 120
ISMSVAGSRQ GACFGGAGGF GTGGFGAGGF GAGFGTGGFG GGFGGSFSGK GGPGFPVCPA
130 140 150 160 170 180
GGIQEVTINQ SLLTPLHVEI DPEIQKVRTE EREQIKLLNN KFASFIDKVQ FLEQQNKVLE
190 200 210 220 230 240
TKWNLLQQQT TTTSSKNLEP LFETYLSVLR KQLDTLGNDK GRLQSELKTM QDSVEDFKTK
250 260 270 280 290 300
YEEEINKRTA AENDFVVLKK DVDAAYLNKV ELEAKVDSLN DEINFLKVLY DAELSQMQTH
310 320 330 340 350 360
VSDTSVVLSM DNNRNLDLDS IIAEVRAQYE EIAQRSKAEA EALYQTKVQQ LQISVDQHGD
370 380 390 400 410 420
NLKNTKSEIA ELNRMIQRLR AEIENIKKQC QTLQVSVADA EQRGENALKD AHSKRVELEA
430 440 450 460 470 480
ALQQAKEELA RMLREYQELM SVKLALDIEI ATYRKLLEGE EYRMSGECQS AVSISVVSGS
490 500 510 520 530
TSTGGISGGL GSGSGFGLSS GFGSGSGSGF GFGGSVSGSS SSKIISTTTL NKRR
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P19013-1-unknown | MIARQQ... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P19013-360-unknown | DNLKNT... | 360 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17418 | |||
| P19013-360-unknown | DNLKNT... | 360 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18832 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...VDQHGD | 359 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17418 | |||
| ...VDQHGD | 359 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18832 | |||
| ...LNKRR | 534 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| MEP1A_HUMAN | 359 | QHGD.|.DNLK | inferred from experiment | unknown | MEROPS | Overall CM | Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) | 21693781, |
| MEP1B_HUMAN | 359 | QHGD.|.DNLK | inferred from experiment | unknown | MEROPS | Overall CM | Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) | 21693781, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|