O94985: Calsyntenin-1

General Information

Protein names	- Calsyntenin-1 - Alcadein-alpha - Alc-alpha - Alzheimer-related cadherin-like protein - Non-classical cadherin XB31alpha - Soluble Alc-alpha - SAlc-alpha - CTF1-alpha - C-terminal fragment 1-alpha
Gene names	CLSTN1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O94985

5 N-termini

4 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLRRPAPALA PAARLLLAGL LCGGGVWAAR VNKHKPWLEP TYHGIVTEND NTVLLDPPLI
        70         80         90        100        110        120
ALDKDAPLRF AESFEVTVTK EGEICGFKIH GQNVPFDAVV VDKSTGEGVI RSKEKLDCEL
       130        140        150        160        170        180
QKDYSFTIQA YDCGKGPDGT NVKKSHKATV HIQVNDVNEY APVFKEKSYK ATVIEGKQYD
       190        200        210        220        230        240
SILRVEAVDA DCSPQFSQIC SYEIITPDVP FTVDKDGYIK NTEKLNYGKE HQYKLTVTAY
       250        260        270        280        290        300
DCGKKRATED VLVKISIKPT CTPGWQGWNN RIEYEPGTGA LAVFPNIHLE TCDEPVASVQ
       310        320        330        340        350        360
ATVELETSHI GKGCDRDTYS EKSLHRLCGA AAGTAELLPS PSGSLNWTMG LPTDNGHDSD
       370        380        390        400        410        420
QVFEFNGTQA VRIPDGVVSV SPKEPFTISV WMRHGPFGRK KETILCSSDK TDMNRHHYSL
       430        440        450        460        470        480
YVHGCRLIFL FRQDPSEEKK YRPAEFHWKL NQVCDEEWHH YVLNVEFPSV TLYVDGTSHE
       490        500        510        520        530        540
PFSVTEDYPL HPSKIETQLV VGACWQEFSG VENDNETEPV TVASAGGDLH MTQFFRGNLA
       550        560        570        580        590        600
GLTLRSGKLA DKKVIDCLYT CKEGLDLQVL EDSGRGVQIQ AHPSQLVLTL EGEDLGELDK
       610        620        630        640        650        660
AMQHISYLNS RQFPTPGIRR LKITSTIKCF NEATCISVPP VDGYVMVLQP EEPKISLSGV
       670        680        690        700        710        720
HHFARAASEF ESSEGVFLFP ELRIISTITR EVEPEGDGAE DPTVQESLVS EEIVHDLDTC
       730        740        750        760        770        780
EVTVEGEELN HEQESLEVDM ARLQQKGIEV SSSELGMTFT GVDTMASYEE VLHLLRYRNW
       790        800        810        820        830        840
HARSLLDRKF KLICSELNGR YISNEFKVEV NVIHTANPME HANHMAAQPQ FVHPEHRSFV
       850        860        870        880        890        900
DLSGHNLANP HPFAVVPSTA TVVIVVCVSF LVFMIILGVF RIRAAHRRTM RDQDTGKENE
       910        920        930        940        950        960
MDWDDSALTI TVNPMETYED QHSSEEEEEE EEEEESEDGE EEDDITSAES ESSEEEEGEQ
       970        980
GDPQNATRQQ QLEWDDSTLS Y

Isoforms

- Isoform 2 of Calsyntenin-1

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O94985-1-unknown	MLRRPA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71947
O94985-29-unknown	ARVNKH...	29	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O94985-29-unknown	ARVNKH...	29	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114517
O94985-56-unknown	DPPLIA...	56	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16972
O94985-56-unknown	DPPLIA...	56	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18325
O94985-97-unknown	DAVVVD...	97	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16974
O94985-97-unknown	DAVVVD...	97	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18327
O94985-97-unknown	DAVVVD...	97	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141663
O94985-826-unknown	AAQPQF...	826	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O94985-826-unknown	AAQPQF...	826	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt116379

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NTVLLD	55	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16972
...NTVLLD	55	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18325
...NTVLLD	55	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122690
...QNVPFD	96	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16974
...QNVPFD	96	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18327
...HANHMA	825	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...HANHMA	825	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt93414
...STLSY	981	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...STLSY	981	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67565

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	55	VLLD.\|.DPPL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	55	VLLD.\|.DPPL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	96	VPFD.\|.DAVV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	96	VPFD.\|.DAVV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)