Q9UH65: Switch-associated protein 70

General Information

Protein names	- Switch-associated protein 70 - SWAP-70
Gene names	SWAP70
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UH65

3 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGSLKEELLK AIWHAFTALD QDHSGKVSKS QLKVLSHNLC TVLKVPHDPV ALEEHFRDDD
        70         80         90        100        110        120
EGPVSNQGYM PYLNRFILEK VQDNFDKIEF NRMCWTLCVK KNLTKNPLLI TEEDAFKIWV
       130        140        150        160        170        180
IFNFLSEDKY PLIIVSEEIE YLLKKLTEAM GGGWQQEQFE HYKINFDDSK NGLSAWELIE
       190        200        210        220        230        240
LIGNGQFSKG MDRQTVSMAI NEVFNELILD VLKQGYMMKK GHRRKNWTER WFVLKPNIIS
       250        260        270        280        290        300
YYVSEDLKDK KGDILLDENC CVESLPDKDG KKCLFLVKCF DKTFEISASD KKKKQEWIQA
       310        320        330        340        350        360
IHSTIHLLKL GSPPPHKEAR QRRKELRKKQ LAEQEELERQ MKELQAANES KQQELEAVRK
       370        380        390        400        410        420
KLEEAASRAA EEEKKRLQTQ VELQARFSTE LEREKLIRQQ MEEQVAQKSS ELEQYLQRVR
       430        440        450        460        470        480
ELEDMYLKLQ EALEDERQAR QDEETVRKLQ ARLLEEESSK RAELEKWHLE QQQAIQTTEA
       490        500        510        520        530        540
EKQELENQRV LKEQALQEAM EQLEQLELER KQALEQYEEV KKKLEMATNK TKSWKDKVAH
       550        560        570        580
HEGLIRLIEP GSKNPHLITN WGPAAFTEAE LEEREKNWKE KKTTE

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9UH65-1-unknown	MGSLKE...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9UH65-150-unknown	MGGGWQ...	150	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435587
Q9UH65-402-unknown	EEQVAQ...	402	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19835
Q9UH65-402-unknown	EEQVAQ...	402	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18160

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EEEKKR	375	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435587
...IRQQME	401	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19835
...IRQQME	401	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18160
...KKTTE	585	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	401	QQME.\|.EEQV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	401	QQME.\|.EEQV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)