P08865: 40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}

General Information

Protein names	- 40S ribosomal protein SA {ECO:0000255\|HAMAP-Rule:MF_03016} - 37 kDa laminin receptor precursor {ECO:0000255\|HAMAP-Rule:MF_03016} - 37LRP {ECO:0000255\|HAMAP-Rule:MF_03016} - 37/67 kDa laminin receptor {ECO:0000255\|HAMAP-Rule:MF_03016} - LRP/LR {ECO:0000255\|HAMAP-Rule:MF_03016} - 67 kDa laminin receptor {ECO:0000255\|HAMAP-Rule:MF_03016} - 67LR {ECO:0000255\|HAMAP-Rule:MF_03016} - Colon carcinoma laminin-binding protein - Laminin receptor 1 {ECO:0000255\|HAMAP-Rule:MF_03016} - LamR {ECO:0000255\|HAMAP-Rule:MF_03016} - Laminin-binding protein precursor p40 {ECO:0000255\|HAMAP-Rule:MF_03016} - LBP/p40 {ECO:0000255\|HAMAP-Rule:MF_03016} - Multidrug resistance-associated protein MGr1-Ag - NEM/1CHD4 - Small ribosomal subunit protein uS2 {ECO:0000303\|PubMed:24524803}
Gene names	RPSA
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P08865

9 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSGALDVLQM KEEDVLKFLA AGTHLGGTNL DFQMEQYIYK RKSDGIYIIN LKRTWEKLLL
        70         80         90        100        110        120
AARAIVAIEN PADVSVISSR NTGQRAVLKF AAATGATPIA GRFTPGTFTN QIQAAFREPR
       130        140        150        160        170        180
LLVVTDPRAD HQPLTEASYV NLPTIALCNT DSPLRYVDIA IPCNNKGAHS VGLMWWMLAR
       190        200        210        220        230        240
EVLRMRGTIS REHPWEVMPD LYFYRDPEEI EKEEQAAAEK AVTKEEFQGE WTAPAPEFTA
       250        260        270        280        290
TQPEVADWSE GVQVPSVPIQ QFPTEDWSAQ PATEDWSAAP TAQATEWVGA TTDWS

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

9 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P08865-2-unknown	MSGALD...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P08865-2-Acetylation	SGALDV...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P08865-2-Acetylation	SGALDV...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P08865-22-unknown	GTHLGG...	22		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3545
P08865-61-unknown	AARAIV...	61		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P08865-90-	FAAATG...	90			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P08865-90-	FAAATG...	90			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P08865-90-	FAAATG...	90			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P08865-90-	FAAATG...	90			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P08865-90-	FAAATG...	90			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P08865-91-	AAATGA...	91			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P08865-192-unknown	EHPWEV...	192		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17236
P08865-201-	LYFYRD...	201			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P08865-203-	FYRDPE...	203			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KFLAAG	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3545
...GTISRE	191	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17236
...IQQFPT	263	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000410848
...TTDWS	295	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	21	LAAG.\|.GTHL	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	191	ISRE.\|.EHPW	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)