P09972: Fructose-bisphosphate aldolase C

General Information

Protein names	- Fructose-bisphosphate aldolase C - 4.1.2.13 - Brain-type aldolase
Gene names	ALDOC
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P09972

10 N-termini

11 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPHSYPALSA EQKKELSDIA LRIVAPGKGI LAADESVGSM AKRLSQIGVE NTEENRRLYR
        70         80         90        100        110        120
QVLFSADDRV KKCIGGVIFF HETLYQKDDN GVPFVRTIQD KGIVVGIKVD KGVVPLAGTD
       130        140        150        160        170        180
GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKISERTPS ALAILENANV LARYASICQQ
       190        200        210        220        230        240
NGIVPIVEPE ILPDGDHDLK RCQYVTEKVL AAVYKALSDH HVYLEGTLLK PNMVTPGHAC
       250        260        270        280        290        300
PIKYTPEEIA MATVTALRRT VPPAVPGVTF LSGGQSEEEA SFNLNAINRC PLPRPWALTF
       310        320        330        340        350        360
SYGRALQASA LNAWRGQRDN AGAATEEFIK RAEVNGLAAQ GKYEGSGEDG GAAAQSLYIA

NHAY

Isoforms

Sequence View

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Evidence Codes:

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Evidence Names:

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Protein Neighborhood

Domains & Features

10 N-termini - 11 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P09972-2-unknown	PHSYPA...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P09972-2-unknown	PHSYPA...	2	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P09972-2-unknown	PHSYPA...	2		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P09972-40-unknown	MAKRLS...	40	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000465623
P09972-107-unknown	IKVDKG...	107	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5528
P09972-118-unknown	GTDGET...	118	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7273
P09972-119-unknown	TDGETT...	119	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3572
P09972-121-	GETTTQ...	121		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P09972-182-unknown	GIVPIV...	182	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17264
P09972-182-	GIVPIV...	182		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P09972-183-unknown	IVPIVE...	183	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17265
P09972-336-	GLAAQG...	336		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GIVVGI	106	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5528
...VVPLAG	117	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7273
...VPLAGT	118	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3572
...GTDGET	122	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463118
...FAKWRC	149	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000398976
...VLARYA	174	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000465623
...LARYAS	175	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462674
...SICQQN	180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463174
...ICQQNG	181	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17264
...CQQNGI	182	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17265
...ANHAY	364	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	106	VVGI.\|.IKVD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	117	PLAG.\|.GTDG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	118	LAGT.\|.TDGE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	181	QQNG.\|.GIVP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	182	QNGI.\|.IVPI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)