P80723: Brain acid soluble protein 1

General Information

Protein names	- Brain acid soluble protein 1 - 22 kDa neuronal tissue-enriched acidic protein - Neuronal axonal membrane protein NAP-22
Gene names	BASP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P80723

16 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGGKLSKKKK GYNVNDEKAK EKDKKAEGAA TEEEGTPKES EPQAAAEPAE AKEGKEKPDQ
        70         80         90        100        110        120
DAEGKAEEKE GEKDAAAAKE EAPKAEPEKT EGAAEAKAEP PKAPEQEQAA PGPAAGGEAP
       130        140        150        160        170        180
KAAEAAAAPA ESAAPAAGEE PSKEEGEPKK TEAPAAPAAQ ETKSDGAPAS DSKPGSSEAA
       190        200        210        220
PSSKETPAAT EAPSSTPKAQ GPAASAEEPK PVEAPAANSD QTVTVKE

Isoforms

- Isoform 2 of Brain acid soluble protein 1

Sequence View

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Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

16 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P80723-1-unknown	MGGKLS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt68224
P80723-2-unknown	GGKLSK...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P80723-2-unknown	GGKLSK...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111341
P80723-98-	AEPPKA...	98		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P80723-98-	AEPPKA...	98		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P80723-107-unknown	EQAAPG...	107	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19298
P80723-110-unknown	APGPAA...	110	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17817
P80723-127-	AAPAES...	127		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P80723-132-	SAAPAA...	132		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P80723-132-	SAAPAA...	132		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P80723-132-	SAAPAA...	132		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P80723-166-	GAPASD...	166		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P80723-166-	GAPASD...	166		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P80723-166-	GAPASD...	166		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P80723-166-	GAPASD...	166		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P80723-166-	GAPASD...	166		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P80723-166-	GAPASD...	166		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P80723-166-unknown	GAPASD...	166	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1265
P80723-166-unknown	GAPASD...	166	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143094
P80723-169-unknown	ASDSKP...	169	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165046
P80723-169-	ASDSKP...	169		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P80723-170-unknown	SDSKPG...	170	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164209
P80723-170-	SDSKPG...	170		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P80723-170-	SDSKPG...	170		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P80723-170-	SDSKPG...	170		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P80723-170-	SDSKPG...	170		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P80723-171-unknown	DSKPGS...	171	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19299
P80723-171-unknown	DSKPGS...	171	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143322
P80723-172-unknown	SKPGSS...	172	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165048
P80723-172-	SKPGSS...	172		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KAPEQE	106	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19298
...EQEQAA	109	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17817
...ETKSDG	165	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1265
...ETKSDG	165	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126312
...GAPASD	170	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19299
...GAPASD	170	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126553
...VTVKE	227	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...VTVKE	227	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt63842

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	106	PEQE.\|.EQAA	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	109	EQAA.\|.APGP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CASP1_HUMAN	165	KSDG.\|.GAPA	inferred from experiment	unknown	MEROPS	Wells JA	Agard NJ et al.:Inflammatory stimuli regulate c... (C14.001)	20173201,
MEP1B_HUMAN	170	PASD.\|.DSKP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)