Q13151: Heterogeneous nuclear ribonucleoprotein A0

General Information

Protein names	- Heterogeneous nuclear ribonucleoprotein A0 - hnRNP A0
Gene names	HNRNPA0
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13151

11 N-termini

4 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MENSQLCKLF IGGLNVQTSE SGLRGHFEAF GTLTDCVVVV NPQTKRSRCF GFVTYSNVEE
        70         80         90        100        110        120
ADAAMAASPH AVDGNTVELK RAVSREDSAR PGAHAKVKKL FVGGLKGDVA EGDLIEHFSQ
       130        140        150        160        170        180
FGTVEKAEII ADKQSGKKRG FGFVYFQNHD AADKAAVVKF HPIQGHRVEV KKAVPKEDIY
       190        200        210        220        230        240
SGGGGGGSRS SRGGRGGRGR GGGRDQNGLS KGGGGGYNSY GGYGGGGGGG YNAYGGGGGG
       250        260        270        280        290        300
SSYGGSDYGN GFGGFGSYSQ HQSSYGPMKS GGGGGGGGSS WGGRSNSGPY RGGYGGGGGY

GGSSF

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

11 N-termini - 4 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13151-1-Acetylation	MENSQL...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13151-1-Acetylation	MENSQL...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q13151-1-Acetylation	MENSQL...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q13151-37-	VVVVNP...	37			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q13151-63-	AAMAAS...	63			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q13151-66-	AASPHA...	66			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q13151-67-unknown	ASPHAV...	67		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7759
Q13151-67-unknown	ASPHAV...	67		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6312
Q13151-101-	FVGGLK...	101			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q13151-143-unknown	FVYFQN...	143		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3978
Q13151-150-unknown	DAADKA...	150		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19407
Q13151-150-unknown	DAADKA...	150		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17884
Q13151-156-	AVVKFH...	156			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q13151-173-	AVPKED...	173			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q13151-173-	AVPKED...	173			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q13151-173-	AVPKED...	173			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q13151-173-	AVPKED...	173			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q13151-251-	GFGGFG...	251			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DAAMAA	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7759
...DAAMAA	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6312
...KRGFGF	142	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3978
...YFQNHD	149	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19407
...YFQNHD	149	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17884
...GGSSF	305	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	66	AMAA.\|.ASPH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	66	AMAA.\|.ASPH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	142	GFGF.\|.FVYF	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1B_HUMAN	149	QNHD.\|.DAAD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	149	QNHD.\|.DAAD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)