P07741: Adenine phosphoribosyltransferase

General Information

Protein names	- Adenine phosphoribosyltransferase - APRT - 2.4.2.7
Gene names	APRT
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P07741

8 N-termini

5 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADSELQLVE QRIRSFPDFP TPGVVFRDIS PVLKDPASFR AAIGLLARHL KATHGGRIDY
        70         80         90        100        110        120
IAGLDSRGFL FGPSLAQELG LGCVLIRKRG KLPGPTLWAS YSLEYGKAEL EIQKDALEPG
       130        140        150        160        170        180
QRVVVVDDLL ATGGTMNAAC ELLGRLQAEV LECVSLVELT SLKGREKLAP VPFFSLLQYE

Isoforms

- Isoform 2 of Adenine phosphoribosyltransferase

Sequence View

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Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

8 N-termini - 5 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P07741-2-unknown	MADSEL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P07741-1-unknown	MADSEL...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt67277
P07741-2-Acetylation	ADSELQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P07741-2-Acetylation	ADSELQ...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P07741-2-Acetylation	ADSELQ...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P07741-2-Acetylation	ADSELQ...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P07741-2-Acetylation	ADSELQ...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P07741-2-Acetylation	ADSELQ...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110680
P07741-15-	SFPDFP...	15			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P07741-15-unknown	SFPDFP...	15		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171809
P07741-19-unknown	FPTPGV...	19		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17181
P07741-19-unknown	FPTPGV...	19		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136766
P07741-34-unknown	KDPASF...	34		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5448
P07741-34-unknown	KDPASF...	34		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt137862
P07741-138-unknown	AACELL...	138		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11099

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...RSFPDF	18	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17181
...ISPVLK	33	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5448
...ISPVLK	33	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt120867
...GGTMNA	137	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11099
...LLQYE	180		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...LLQYE	180		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...LLQYE	180	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...LLQYE	180		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...LLQYE	180		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	18	FPDF.\|.FPTP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	33	PVLK.\|.KDPA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	137	TMNA.\|.AACE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)