P31689: DnaJ homolog subfamily A member 1

General Information

Protein names	- DnaJ homolog subfamily A member 1 - DnaJ protein homolog 2 - HSDJ - Heat shock 40 kDa protein 4 - Heat shock protein J2 - HSJ-2 - Human DnaJ protein 2 - hDj-2
Gene names	DNAJA1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P31689

8 N-termini

5 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVKETTYYDV LGVKPNATQE ELKKAYRKLA LKYHPDKNPN EGEKFKQISQ AYEVLSDAKK
        70         80         90        100        110        120
RELYDKGGEQ AIKEGGAGGG FGSPMDIFDM FFGGGGRMQR ERRGKNVVHQ LSVTLEDLYN
       130        140        150        160        170        180
GATRKLALQK NVICDKCEGR GGKKGAVECC PNCRGTGMQI RIHQIGPGMV QQIQSVCMEC
       190        200        210        220        230        240
QGHGERISPK DRCKSCNGRK IVREKKILEV HIDKGMKDGQ KITFHGEGDQ EPGLEPGDII
       250        260        270        280        290        300
IVLDQKDHAV FTRRGEDLFM CMDIQLVEAL CGFQKPISTL DNRTIVITSH PGQIVKHGDI
       310        320        330        340        350        360
KCVLNEGMPI YRRPYEKGRL IIEFKVNFPE NGFLSPDKLS LLEKLLPERK EVEETDEMDQ
       370        380        390
VELVDFDPNQ ERRRHYNGEA YEDDEHHPRG GVQCQTS

Isoforms

- Isoform 2 of DnaJ homolog subfamily A member 1

Sequence View

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Protein Neighborhood

Domains & Features

8 N-termini - 5 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P31689-1-unknown	MVKETT...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P31689-1-unknown	MVKETT...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt73041
P31689-2-	VKETTY...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P31689-2-unknown	VKETTY...	2		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P31689-2-unknown	VKETTY...	2		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P31689-2-unknown	VKETTY...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162553
P31689-12-unknown	GVKPNA...	12	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5783
P31689-12-unknown	GVKPNA...	12	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136367
P31689-13-unknown	VKPNAT...	13	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5785
P31689-13-unknown	VKPNAT...	13	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7423
P31689-13-unknown	VKPNAT...	13	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136389
P31689-289-unknown	SHPGQI...	289	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7425
P31689-289-unknown	SHPGQI...	289	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149555
P31689-332-	GFLSPD...	332		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P31689-335-unknown	SPDKLS...	335	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17572

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YYDVLG	11	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5783
...YDVLGV	12	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5785
...YDVLGV	12	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7423
...TIVITS	288	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7425
...TIVITS	288	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132943
...ENGFLS	334	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17572
...GGVQCQ	394	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	11	DVLG.\|.GVKP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	12	VLGV.\|.VKPN	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	12	VLGV.\|.VKPN	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	288	VITS.\|.SHPG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	334	GFLS.\|.SPDK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)