TopFIND 4.0

P42677: 40S ribosomal protein S27

General Information

Protein names	- 40S ribosomal protein S27 - Metallopan-stimulin 1 - MPS-1 - Small ribosomal subunit protein eS27 {ECO:0000303\|PubMed:24524803}
Gene names	RPS27
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P42677

4

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MPLAKDLLHP SPEEEKRKHK KKRLVQSPNS YFMDVKCPGC YKITTVFSHA QTVVLCVGCS
70 80
TVLCQPTGGK ARLTEGCSFR RKQH

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P42677-2-	PLAKDL...	2			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P42677-2-	PLAKDL...	2			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P42677-2-	PLAKDL...	2			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P42677-2-unknown	PLAKDL...	2		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P42677-2-unknown	PLAKDL...	2			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P42677-2-unknown	PLAKDL...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P42677-6-unknown	DLLHPS...	6		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17647
P42677-24-	LVQSPN...	24			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...MPLAKD	5	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17647
	...RRKQH	84	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	5	LAKD.\|.DLLH	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)