Q12791: Calcium-activated potassium channel subunit alpha-1

General Information

Protein names	- Calcium-activated potassium channel subunit alpha-1 - BK channel - BKCA alpha - Calcium-activated potassium channel, subfamily M subunit alpha-1 - K(VCA)alpha - KCa1.1 - Maxi K channel - MaxiK - Slo-alpha - Slo1 - Slowpoke homolog - Slo homolog - hSlo
Gene names	KCNMA1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q12791

7 N-termini

2 C-termini

3 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Calcium-activated potassium channel subunit alpha-1 - Isoform 3 of Calcium-activated potassium channel subunit alpha-1 - Isoform 4 of Calcium-activated potassium channel subunit alpha-1 - Isoform 5 of Calcium-activated potassium channel subunit alpha-1 - Isoform 6 of Calcium-activated potassium channel subunit alpha-1 - Isoform 7 of Calcium-activated potassium channel subunit alpha-1

Sequence View

        10         20         30         40         50         60
MANGGGGGGG SSGGGGGGGG SSLRMSSNIH ANHLSLDASS SSSSSSSSSS SSSSSSSSSS
        70         80         90        100        110        120
VHEPKMDALI IPVTMEVPCD SRGQRMWWAF LASSMVTFFG GLFIILLWRT LKYLWTVCCH
       130        140        150        160        170        180
CGGKTKEAQK INNGSSQADG TLKPVDEKEE AVAAEVGWMT SVKDWAGVMI SAQTLTGRVL
       190        200        210        220        230        240
VVLVFALSIG ALVIYFIDSS NPIESCQNFY KDFTLQIDMA FNVFFLLYFG LRFIAANDKL
       250        260        270        280        290        300
WFWLEVNSVV DFFTVPPVFV SVYLNRSWLG LRFLRALRLI QFSEILQFLN ILKTSNSIKL
       310        320        330        340        350        360
VNLLSIFIST WLTAAGFIHL VENSGDPWEN FQNNQALTYW ECVYLLMVTM STVGYGDVYA
       370        380        390        400        410        420
KTTLGRLFMV FFILGGLAMF ASYVPEIIEL IGNRKKYGGS YSAVSGRKHI VVCGHITLES
       430        440        450        460        470        480
VSNFLKDFLH KDRDDVNVEI VFLHNISPNL ELEALFKRHF TQVEFYQGSV LNPHDLARVK
       490        500        510        520        530        540
IESADACLIL ANKYCADPDA EDASNIMRVI SIKNYHPKIR IITQMLQYHN KAHLLNIPSW
       550        560        570        580        590        600
NWKEGDDAIC LAELKLGFIA QSCLAQGLST MLANLFSMRS FIKIEEDTWQ KYYLEGVSNE
       610        620        630        640        650        660
MYTEYLSSAF VGLSFPTVCE LCFVKLKLLM IAIEYKSANR ESRILINPGN HLKIQEGTLG
       670        680        690        700        710        720
FFIASDAKEV KRAFFYCKAC HDDITDPKRI KKCGCKRPKM SIYKRMRRAC CFDCGRSERD
       730        740        750        760        770        780
CSCMSGRVRG NVDTLERAFP LSSVSVNDCS TSFRAFEDEQ PSTLSPKKKQ RNGGMRNSPN
       790        800        810        820        830        840
TSPKLMRHDP LLIPGNDQID NMDSNVKKYD STGMFHWCAP KEIEKVILTR SEAAMTVLSG
       850        860        870        880        890        900
HVVVCIFGDV SSALIGLRNL VMPLRASNFH YHELKHIVFV GSIEYLKREW ETLHNFPKVS
       910        920        930        940        950        960
ILPGTPLSRA DLRAVNINLC DMCVILSANQ NNIDDTSLQD KECILASLNI KSMQFDDSIG
       970        980        990       1000       1010       1020
VLQANSQGFT PPGMDRSSPD NSPVHGMLRQ PSITTGVNIP IITELVNDTN VQFLDQDDDD
      1030       1040       1050       1060       1070       1080
DPDTELYLTQ PFACGTAFAV SVLDSLMSAT YFNDNILTLI RTLVTGGATP ELEALIAEEN
      1090       1100       1110       1120       1130       1140
ALRGGYSTPQ TLANRDRCRV AQLALLDGPF ADLGDGGCYG DLFCKALKTY NMLCFGIYRL
      1150       1160       1170       1180       1190       1200
RDAHLSTPSQ CTKRYVITNP PYEFELVPTD LIFCLMQFDH NAGQSRASLS HSSHSSQSSS
      1210       1220       1230
KKSSSVHSIP STANRQNRPK SRESRDKQKY VQEERL         10         20         30         40         50         60
MANGGGGGGG SSGGGGGGGG SSLRMSSNIH ANHLSLDASS SSSSSSSSSS SSSSSSSSSS
        70         80         90        100        110        120
VHEPKMDALI IPVTMEVPCD SRGQRMWWAF LASSMVTFFG GLFIILLWRT LKYLWTVCCH
       130        140        150        160        170        180
CGGKTKEAQK INNGSSQADG TLKPVDEKEE AVAAEVGWMT SVKDWAGVMI SAQTLTGRVL
       190        200        210        220        230        240
VVLVFALSIG ALVIYFIDSS NPIESCQNFY KDFTLQIDMA FNVFFLLYFG LRFIAANDKL
       250        260        270        280        290        300
WFWLEVNSVV DFFTVPPVFV SVYLNRSWLG LRFLRALRLI QFSEILQFLN ILKTSNSIKL
       310        320        330        340        350        360
VNLLSIFIST WLTAAGFIHL VENSGDPWEN FQNNQALTYW ECVYLLMVTM STVGYGDVYA
       370        380        390        400        410        420
KTTLGRLFMV FFILGGLAMF ASYVPEIIEL IGNRKKYGGS YSAVSGRKHI VVCGHITLES
       430        440        450        460        470        480
VSNFLKDFLH KDRDDVNVEI VFLHNISPNL ELEALFKRHF TQVEFYQGSV LNPHDLARVK
       490        500        510        520        530        540
IESADACLIL ANKYCADPDA EDASNIMRVI SIKNYHPKIR IITQMLQYHN KAHLLNIPSW
       550        560        570        580        590        600
NWKEGDDAIC LAELKLGFIA QSCLAQGLST MLANLFSMRS FIKIEEDTWQ KYYLEGVSNE
       610        620        630        640        650        660
MYTEYLSSAF VGLSFPTVCE LCFVKLKLLM IAIEYKSANR ESRILINPGN HLKIQEGTLG
       670        680        690        700        710        720
FFIASDAKEV KRAFFYCKAC HDDITDPKRI KKCGCKRPKM SIYKRMRRAC CFDCGRSERD
       730        740        750        760        770        780
CSCMSGRVRG NVDTLERAFP LSSVSVNDCS TSFRAFEDEQ PSTLSPKKKQ RNGGMRNSPN
       790        800        810        820        830        840
TSPKLMRHDP LLIPGNDQID NMDSNVKKYD STGMFHWCAP KEIEKVILTR SEAAMTVLSG
       850        860        870        880        890        900
HVVVCIFGDV SSALIGLRNL VMPLRASNFH YHELKHIVFV GSIEYLKREW ETLHNFPKVS
       910        920        930        940        950        960
ILPGTPLSRA DLRAVNINLC DMCVILSANQ NNIDDTSLQD KECILASLNI KSMQFDDSIG
       970        980        990       1000       1010       1020
VLQANSQGFT PPGMDRSSPD NSPVHGMLRQ PSITTGVNIP IITELVNDTN VQFLDQDDDD
      1030       1040       1050       1060       1070       1080
DPDTELYLTQ PFACGTAFAV SVLDSLMSAT YFNDNILTLI RTLVTGGATP ELEALIAEEN
      1090       1100       1110       1120       1130       1140
ALRGGYSTPQ TLANRDRCRV AQLALLDGPF ADLGDGGCYG DLFCKALKTY NMLCFGIYRL
      1150       1160       1170       1180       1190       1200
RDAHLSTPSQ CTKRYVITNP PYEFELVPTD LIFCLMQFDH NAGQSRASLS HSSHSSQSSS
      1210       1220       1230
KKSSSVHSIP STANRQNRPK SRESRDKQKY VQEERL         10         20         30         40         50         60
MANGGGGGGG SSGGGGGGGG SSLRMSSNIH ANHLSLDASS SSSSSSSSSS SSSSSSSSSS
        70         80         90        100        110        120
VHEPKMDALI IPVTMEVPCD SRGQRMWWAF LASSMVTFFG GLFIILLWRT LKYLWTVCCH
       130        140        150        160        170        180
CGGKTKEAQK INNGSSQADG TLKPVDEKEE AVAAEVGWMT SVKDWAGVMI SAQTLTGRVL
       190        200        210        220        230        240
VVLVFALSIG ALVIYFIDSS NPIESCQNFY KDFTLQIDMA FNVFFLLYFG LRFIAANDKL
       250        260        270        280        290        300
WFWLEVNSVV DFFTVPPVFV SVYLNRSWLG LRFLRALRLI QFSEILQFLN ILKTSNSIKL
       310        320        330        340        350        360
VNLLSIFIST WLTAAGFIHL VENSGDPWEN FQNNQALTYW ECVYLLMVTM STVGYGDVYA
       370        380        390        400        410        420
KTTLGRLFMV FFILGGLAMF ASYVPEIIEL IGNRKKYGGS YSAVSGRKHI VVCGHITLES
       430        440        450        460        470        480
VSNFLKDFLH KDRDDVNVEI VFLHNISPNL ELEALFKRHF TQVEFYQGSV LNPHDLARVK
       490        500        510        520        530        540
IESADACLIL ANKYCADPDA EDASNIMRVI SIKNYHPKIR IITQMLQYHN KAHLLNIPSW
       550        560        570        580        590        600
NWKEGDDAIC LAELKLGFIA QSCLAQGLST MLANLFSMRS FIKIEEDTWQ KYYLEGVSNE
       610        620        630        640        650        660
MYTEYLSSAF VGLSFPTVCE LCFVKLKLLM IAIEYKSANR ESRILINPGN HLKIQEGTLG
       670        680        690        700        710        720
FFIASDAKEV KRAFFYCKAC HDDITDPKRI KKCGCKRPKM SIYKRMRRAC CFDCGRSERD
       730        740        750        760        770        780
CSCMSGRVRG NVDTLERAFP LSSVSVNDCS TSFRAFEDEQ PSTLSPKKKQ RNGGMRNSPN
       790        800        810        820        830        840
TSPKLMRHDP LLIPGNDQID NMDSNVKKYD STGMFHWCAP KEIEKVILTR SEAAMTVLSG
       850        860        870        880        890        900
HVVVCIFGDV SSALIGLRNL VMPLRASNFH YHELKHIVFV GSIEYLKREW ETLHNFPKVS
       910        920        930        940        950        960
ILPGTPLSRA DLRAVNINLC DMCVILSANQ NNIDDTSLQD KECILASLNI KSMQFDDSIG
       970        980        990       1000       1010       1020
VLQANSQGFT PPGMDRSSPD NSPVHGMLRQ PSITTGVNIP IITELVNDTN VQFLDQDDDD
      1030       1040       1050       1060       1070       1080
DPDTELYLTQ PFACGTAFAV SVLDSLMSAT YFNDNILTLI RTLVTGGATP ELEALIAEEN
      1090       1100       1110       1120       1130       1140
ALRGGYSTPQ TLANRDRCRV AQLALLDGPF ADLGDGGCYG DLFCKALKTY NMLCFGIYRL
      1150       1160       1170       1180       1190       1200
RDAHLSTPSQ CTKRYVITNP PYEFELVPTD LIFCLMQFDH NAGQSRASLS HSSHSSQSSS
      1210       1220       1230
KKSSSVHSIP STANRQNRPK SRESRDKQKY VQEERL         10         20         30         40         50         60
MANGGGGGGG SSGGGGGGGG SSLRMSSNIH ANHLSLDASS SSSSSSSSSS SSSSSSSSSS
        70         80         90        100        110        120
VHEPKMDALI IPVTMEVPCD SRGQRMWWAF LASSMVTFFG GLFIILLWRT LKYLWTVCCH
       130        140        150        160        170        180
CGGKTKEAQK INNGSSQADG TLKPVDEKEE AVAAEVGWMT SVKDWAGVMI SAQTLTGRVL
       190        200        210        220        230        240
VVLVFALSIG ALVIYFIDSS NPIESCQNFY KDFTLQIDMA FNVFFLLYFG LRFIAANDKL
       250        260        270        280        290        300
WFWLEVNSVV DFFTVPPVFV SVYLNRSWLG LRFLRALRLI QFSEILQFLN ILKTSNSIKL
       310        320        330        340        350        360
VNLLSIFIST WLTAAGFIHL VENSGDPWEN FQNNQALTYW ECVYLLMVTM STVGYGDVYA
       370        380        390        400        410        420
KTTLGRLFMV FFILGGLAMF ASYVPEIIEL IGNRKKYGGS YSAVSGRKHI VVCGHITLES
       430        440        450        460        470        480
VSNFLKDFLH KDRDDVNVEI VFLHNISPNL ELEALFKRHF TQVEFYQGSV LNPHDLARVK
       490        500        510        520        530        540
IESADACLIL ANKYCADPDA EDASNIMRVI SIKNYHPKIR IITQMLQYHN KAHLLNIPSW
       550        560        570        580        590        600
NWKEGDDAIC LAELKLGFIA QSCLAQGLST MLANLFSMRS FIKIEEDTWQ KYYLEGVSNE
       610        620        630        640        650        660
MYTEYLSSAF VGLSFPTVCE LCFVKLKLLM IAIEYKSANR ESRILINPGN HLKIQEGTLG
       670        680        690        700        710        720
FFIASDAKEV KRAFFYCKAC HDDITDPKRI KKCGCKRPKM SIYKRMRRAC CFDCGRSERD
       730        740        750        760        770        780
CSCMSGRVRG NVDTLERAFP LSSVSVNDCS TSFRAFEDEQ PSTLSPKKKQ RNGGMRNSPN
       790        800        810        820        830        840
TSPKLMRHDP LLIPGNDQID NMDSNVKKYD STGMFHWCAP KEIEKVILTR SEAAMTVLSG
       850        860        870        880        890        900
HVVVCIFGDV SSALIGLRNL VMPLRASNFH YHELKHIVFV GSIEYLKREW ETLHNFPKVS
       910        920        930        940        950        960
ILPGTPLSRA DLRAVNINLC DMCVILSANQ NNIDDTSLQD KECILASLNI KSMQFDDSIG
       970        980        990       1000       1010       1020
VLQANSQGFT PPGMDRSSPD NSPVHGMLRQ PSITTGVNIP IITELVNDTN VQFLDQDDDD
      1030       1040       1050       1060       1070       1080
DPDTELYLTQ PFACGTAFAV SVLDSLMSAT YFNDNILTLI RTLVTGGATP ELEALIAEEN
      1090       1100       1110       1120       1130       1140
ALRGGYSTPQ TLANRDRCRV AQLALLDGPF ADLGDGGCYG DLFCKALKTY NMLCFGIYRL
      1150       1160       1170       1180       1190       1200
RDAHLSTPSQ CTKRYVITNP PYEFELVPTD LIFCLMQFDH NAGQSRASLS HSSHSSQSSS
      1210       1220       1230
KKSSSVHSIP STANRQNRPK SRESRDKQKY VQEERL         10         20         30         40         50         60
MANGGGGGGG SSGGGGGGGG SSLRMSSNIH ANHLSLDASS SSSSSSSSSS SSSSSSSSSS
        70         80         90        100        110        120
VHEPKMDALI IPVTMEVPCD SRGQRMWWAF LASSMVTFFG GLFIILLWRT LKYLWTVCCH
       130        140        150        160        170        180
CGGKTKEAQK INNGSSQADG TLKPVDEKEE AVAAEVGWMT SVKDWAGVMI SAQTLTGRVL
       190        200        210        220        230        240
VVLVFALSIG ALVIYFIDSS NPIESCQNFY KDFTLQIDMA FNVFFLLYFG LRFIAANDKL
       250        260        270        280        290        300
WFWLEVNSVV DFFTVPPVFV SVYLNRSWLG LRFLRALRLI QFSEILQFLN ILKTSNSIKL
       310        320        330        340        350        360
VNLLSIFIST WLTAAGFIHL VENSGDPWEN FQNNQALTYW ECVYLLMVTM STVGYGDVYA
       370        380        390        400        410        420
KTTLGRLFMV FFILGGLAMF ASYVPEIIEL IGNRKKYGGS YSAVSGRKHI VVCGHITLES
       430        440        450        460        470        480
VSNFLKDFLH KDRDDVNVEI VFLHNISPNL ELEALFKRHF TQVEFYQGSV LNPHDLARVK
       490        500        510        520        530        540
IESADACLIL ANKYCADPDA EDASNIMRVI SIKNYHPKIR IITQMLQYHN KAHLLNIPSW
       550        560        570        580        590        600
NWKEGDDAIC LAELKLGFIA QSCLAQGLST MLANLFSMRS FIKIEEDTWQ KYYLEGVSNE
       610        620        630        640        650        660
MYTEYLSSAF VGLSFPTVCE LCFVKLKLLM IAIEYKSANR ESRILINPGN HLKIQEGTLG
       670        680        690        700        710        720
FFIASDAKEV KRAFFYCKAC HDDITDPKRI KKCGCKRPKM SIYKRMRRAC CFDCGRSERD
       730        740        750        760        770        780
CSCMSGRVRG NVDTLERAFP LSSVSVNDCS TSFRAFEDEQ PSTLSPKKKQ RNGGMRNSPN
       790        800        810        820        830        840
TSPKLMRHDP LLIPGNDQID NMDSNVKKYD STGMFHWCAP KEIEKVILTR SEAAMTVLSG
       850        860        870        880        890        900
HVVVCIFGDV SSALIGLRNL VMPLRASNFH YHELKHIVFV GSIEYLKREW ETLHNFPKVS
       910        920        930        940        950        960
ILPGTPLSRA DLRAVNINLC DMCVILSANQ NNIDDTSLQD KECILASLNI KSMQFDDSIG
       970        980        990       1000       1010       1020
VLQANSQGFT PPGMDRSSPD NSPVHGMLRQ PSITTGVNIP IITELVNDTN VQFLDQDDDD
      1030       1040       1050       1060       1070       1080
DPDTELYLTQ PFACGTAFAV SVLDSLMSAT YFNDNILTLI RTLVTGGATP ELEALIAEEN
      1090       1100       1110       1120       1130       1140
ALRGGYSTPQ TLANRDRCRV AQLALLDGPF ADLGDGGCYG DLFCKALKTY NMLCFGIYRL
      1150       1160       1170       1180       1190       1200
RDAHLSTPSQ CTKRYVITNP PYEFELVPTD LIFCLMQFDH NAGQSRASLS HSSHSSQSSS
      1210       1220       1230
KKSSSVHSIP STANRQNRPK SRESRDKQKY VQEERL         10         20         30         40         50         60
MANGGGGGGG SSGGGGGGGG SSLRMSSNIH ANHLSLDASS SSSSSSSSSS SSSSSSSSSS
        70         80         90        100        110        120
VHEPKMDALI IPVTMEVPCD SRGQRMWWAF LASSMVTFFG GLFIILLWRT LKYLWTVCCH
       130        140        150        160        170        180
CGGKTKEAQK INNGSSQADG TLKPVDEKEE AVAAEVGWMT SVKDWAGVMI SAQTLTGRVL
       190        200        210        220        230        240
VVLVFALSIG ALVIYFIDSS NPIESCQNFY KDFTLQIDMA FNVFFLLYFG LRFIAANDKL
       250        260        270        280        290        300
WFWLEVNSVV DFFTVPPVFV SVYLNRSWLG LRFLRALRLI QFSEILQFLN ILKTSNSIKL
       310        320        330        340        350        360
VNLLSIFIST WLTAAGFIHL VENSGDPWEN FQNNQALTYW ECVYLLMVTM STVGYGDVYA
       370        380        390        400        410        420
KTTLGRLFMV FFILGGLAMF ASYVPEIIEL IGNRKKYGGS YSAVSGRKHI VVCGHITLES
       430        440        450        460        470        480
VSNFLKDFLH KDRDDVNVEI VFLHNISPNL ELEALFKRHF TQVEFYQGSV LNPHDLARVK
       490        500        510        520        530        540
IESADACLIL ANKYCADPDA EDASNIMRVI SIKNYHPKIR IITQMLQYHN KAHLLNIPSW
       550        560        570        580        590        600
NWKEGDDAIC LAELKLGFIA QSCLAQGLST MLANLFSMRS FIKIEEDTWQ KYYLEGVSNE
       610        620        630        640        650        660
MYTEYLSSAF VGLSFPTVCE LCFVKLKLLM IAIEYKSANR ESRILINPGN HLKIQEGTLG
       670        680        690        700        710        720
FFIASDAKEV KRAFFYCKAC HDDITDPKRI KKCGCKRPKM SIYKRMRRAC CFDCGRSERD
       730        740        750        760        770        780
CSCMSGRVRG NVDTLERAFP LSSVSVNDCS TSFRAFEDEQ PSTLSPKKKQ RNGGMRNSPN
       790        800        810        820        830        840
TSPKLMRHDP LLIPGNDQID NMDSNVKKYD STGMFHWCAP KEIEKVILTR SEAAMTVLSG
       850        860        870        880        890        900
HVVVCIFGDV SSALIGLRNL VMPLRASNFH YHELKHIVFV GSIEYLKREW ETLHNFPKVS
       910        920        930        940        950        960
ILPGTPLSRA DLRAVNINLC DMCVILSANQ NNIDDTSLQD KECILASLNI KSMQFDDSIG
       970        980        990       1000       1010       1020
VLQANSQGFT PPGMDRSSPD NSPVHGMLRQ PSITTGVNIP IITELVNDTN VQFLDQDDDD
      1030       1040       1050       1060       1070       1080
DPDTELYLTQ PFACGTAFAV SVLDSLMSAT YFNDNILTLI RTLVTGGATP ELEALIAEEN
      1090       1100       1110       1120       1130       1140
ALRGGYSTPQ TLANRDRCRV AQLALLDGPF ADLGDGGCYG DLFCKALKTY NMLCFGIYRL
      1150       1160       1170       1180       1190       1200
RDAHLSTPSQ CTKRYVITNP PYEFELVPTD LIFCLMQFDH NAGQSRASLS HSSHSSQSSS
      1210       1220       1230
KKSSSVHSIP STANRQNRPK SRESRDKQKY VQEERL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 2 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q12791-1-unknown	MANGGG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q12791-1-unknown	MANGGG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78715
Q12791-1-unknown	MANGGG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78716
Q12791-1-unknown	MANGGG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78717
Q12791-1-unknown	MANGGG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78718
Q12791-1-unknown	MANGGG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78719
Q12791-1-unknown	MANGGG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78720
Q12791-3-unknown	NGGGGG...	3	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19387
Q12791-3-unknown	NGGGGG...	3	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17874
Q12791-3-unknown	NGGGGG...	3	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt194551
Q12791-3-unknown	NGGGGG...	3	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt194552
Q12791-3-unknown	NGGGGG...	3	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt194553
Q12791-3-unknown	NGGGGG...	3	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt194554
Q12791-3-unknown	NGGGGG...	3	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt194555
Q12791-3-unknown	NGGGGG...	3	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt194556
Q12791-27-unknown	SNIHAN...	27	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000396608
Q12791-27-unknown	SNIHAN...	27	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195485
Q12791-27-unknown	SNIHAN...	27	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195486
Q12791-27-unknown	SNIHAN...	27	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195487
Q12791-27-unknown	SNIHAN...	27	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195488
Q12791-27-unknown	SNIHAN...	27	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195489
Q12791-27-unknown	SNIHAN...	27	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195490
Q12791-64-unknown	PKMDAL...	64	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000361485
Q12791-64-unknown	PKMDAL...	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196396
Q12791-64-unknown	PKMDAL...	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196397
Q12791-64-unknown	PKMDAL...	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196398
Q12791-64-unknown	PKMDAL...	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196399
Q12791-64-unknown	PKMDAL...	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196400
Q12791-64-unknown	PKMDAL...	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196401
Q12791-66-unknown	MDALII...	66	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000361514
Q12791-66-unknown	MDALII...	66	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196430
Q12791-66-unknown	MDALII...	66	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196431
Q12791-66-unknown	MDALII...	66	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196432
Q12791-66-unknown	MDALII...	66	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196433
Q12791-66-unknown	MDALII...	66	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196434
Q12791-66-unknown	MDALII...	66	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196435
Q12791-140-unknown	GTLKPV...	140	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000473714
Q12791-140-unknown	GTLKPV...	140	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197542
Q12791-140-unknown	GTLKPV...	140	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197543
Q12791-140-unknown	GTLKPV...	140	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197544
Q12791-140-unknown	GTLKPV...	140	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197545
Q12791-140-unknown	GTLKPV...	140	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197546
Q12791-1009-unknown	TNVQFL...	1009	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11947
Q12791-1009-unknown	TNVQFL...	1009	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt157054
Q12791-1009-unknown	TNVQFL...	1009	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt157107
Q12791-1009-unknown	TNVQFL...	1009	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt157139
Q12791-1009-unknown	TNVQFL...	1009	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt157182
Q12791-1009-unknown	TNVQFL...	1009	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt157192

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ELVNDT	1008	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11947
...ELVNDT	1008	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140548
...ELVNDT	1008	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140607
...ELVNDT	1008	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140639
...ELVNDT	1008	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140683
...ELVNDT	1008	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140693
...QEERL	1236	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...QEERL	1236	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74336
...QEERL	1236	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74335
...QEERL	1236	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74333
...QEERL	1236	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74338
...QEERL	1236	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74334

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	2	.\|.NGGG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	2	.\|.NGGG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAB_HUMAN	1008	VNDT.\|.TNVQ	inferred from experiment	unknown	MEROPS	Rogers SW	Gahring L et al.:Granzyme B proteolysis of a neu... (S01.010)	11160179,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)