P52815: 39S ribosomal protein L12, mitochondrial

General Information

Protein names	- 39S ribosomal protein L12, mitochondrial - L12mt - MRP-L12 - 5c5-2 - Mitochondrial large ribosomal subunit protein bL12m {ECO:0000303\|PubMed:25278503}
Gene names	MRPL12
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P52815

9 N-termini

3 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLPAAARPLW GPCLGLRAAA FRLARRQVPC VCAVRHMRSS GHQRCEALAG APLDNAPKEY
        70         80         90        100        110        120
PPKIQQLVQD IASLTLLEIS DLNELLKKTL KIQDVGLVPM GGVMSGAVPA AAAQEAVEED
       130        140        150        160        170        180
IPIAKERTHF TVRLTEAKPV DKVKLIKEIK NYIQGINLVQ AKKLVESLPQ EIKANVAKAE
       190
AEKIKAALEA VGGTVVLE

Isoforms

Sequence View

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Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

9 N-termini - 3 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P52815-46-unknown	EALAGA...	46	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P52815-47-	ALAGAP...	47		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P52815-47-	ALAGAP...	47		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P52815-50-unknown	GAPLDN...	50	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7551
P52815-96-	GLVPMG...	96		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P52815-97-	LVPMGG...	97		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P52815-102-	GVMSGA...	102		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P52815-106-	GAVPAA...	106		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P52815-107-	AVPAAA...	107		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P52815-107-	AVPAAA...	107		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P52815-107-	AVPAAA...	107		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P52815-107-	AVPAAA...	107		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P52815-115-unknown	EAVEED...	115	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17717
P52815-115-unknown	EAVEED...	115	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19190

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...CEALAG	49	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7551
...AAAAQE	114	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17717
...AAAAQE	114	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19190
...TVVLE	198	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	49	ALAG.\|.GAPL	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	114	AAQE.\|.EAVE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	114	AAQE.\|.EAVE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)