Q9NTZ6: RNA-binding protein 12

General Information

Protein names	- RNA-binding protein 12 - RNA-binding motif protein 12 - SH3/WW domain anchor protein in the nucleus - SWAN
Gene names	RBM12
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NTZ6

7 N-termini

10 C-termini

8 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAVVIRLQGL PIVAGTMDIR HFFSGLTIPD GGVHIVGGEL GEAFIVFATD EDARLGMMRT
        70         80         90        100        110        120
GGTIKGSKVT LLLSSKTEMQ NMIELSRRRF ETANLDIPPA NASRSGPPPS SGMSSRVNLP
       130        140        150        160        170        180
TTVSNFNNPS PSVVTATTSV HESNKNIQTF STASVGTAPP NMGASFGSPT FSSTVPSTAS
       190        200        210        220        230        240
PMNTVPPPPI PPIPAMPSLP PMPSIPPIPV PPPVPTLPPV PPVPPIPPVP SVPPMTPLPP
       250        260        270        280        290        300
MSGMPPLNPP PVAPLPAGMN GSGAPMNLNN NLNPMFLGPL NPVNPIQMNS QSSVKPLPIN
       310        320        330        340        350        360
PDDLYVSVHG MPFSAMENDV RDFFHGLRVD AVHLLKDHVG RNNGNGLVKF LSPQDTFEAL
       370        380        390        400        410        420
KRNRMLMIQR YVEVSPATER QWVAAGGHIT FKQNMGPSGQ THPPPQTLPR SKSPSGQKRS
       430        440        450        460        470        480
RSRSPHEAGF CVYLKGLPFE AENKHVIDFF KKLDIVEDSI YIAYGPNGKA TGEGFVEFRN
       490        500        510        520        530        540
EADYKAALCR HKQYMGNRFI QVHPITKKGM LEKIDMIRKR LQNFSYDQRE MILNPEGDVN
       550        560        570        580        590        600
SAKVCAHITN IPFSITKMDV LQFLEGIPVD ENAVHVLVDN NGQGLGQALV QFKNEDDARK
       610        620        630        640        650        660
SERLHRKKLN GREAFVHVVT LEDMREIEKN PPAQGKKGLK MPVPGNPAVP GMPNAGLPGV
       670        680        690        700        710        720
GLPSAGLPGA GLPSTGLPGS AITSAGLPGA GMPSAGIPSA GGEEHAFLTV GSKEANNGPP
       730        740        750        760        770        780
FNFPGNFGGS NAFGPPIPPP GLGGGAFGDA RPGMPSVGNS GLPGLGLDVP GFGGGPNNLS
       790        800        810        820        830        840
GPSGFGGGPQ NFGNGPGSLG GPPGFGSGPP GLGSAPGHLG GPPAFGPGPG PGPGPGPIHI
       850        860        870        880        890        900
GGPPGFASSS GKPGPTVIKV QNMPFTVSID EILDFFYGYQ VIPGSVCLKY NEKGMPTGEA
       910        920        930
MVAFESRDEA TAAVIDLNDR PIGSRKVKLV LG

Isoforms

Sequence View

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Directness:

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Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 10 C-termini - 8 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NTZ6-1-unknown	MAVVIR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NTZ6-293-	SVKPLP...	293		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9NTZ6-385-unknown	AGGHIT...	385	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6808
Q9NTZ6-385-unknown	AGGHIT...	385	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8108
Q9NTZ6-842-unknown	GPPGFA...	842	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6809
Q9NTZ6-846-unknown	FASSSG...	846	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4260
Q9NTZ6-848-unknown	SSSGKP...	848	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6810
Q9NTZ6-848-unknown	SSSGKP...	848	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8109
Q9NTZ6-849-unknown	SSGKPG...	849	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4261
Q9NTZ6-849-unknown	SSGKPG...	849	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8110

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...SPSVVT	134	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000411692
...SVHESN	143	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000392642
...QMNSQS	291	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000411036
...RQWVAA	384	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6808
...RQWVAA	384	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8108
...PIHIGG	841	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6809
...GGPPGF	845	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4260
...PPGFAS	847	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6810
...PPGFAS	847	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8109
...PGFASS	848	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4261
...PGFASS	848	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8110
...KLVLG	932	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...KLVLG	932		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...KLVLG	932		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	384	WVAA.\|.AGGH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	384	WVAA.\|.AGGH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	841	HIGG.\|.GPPG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	845	PPGF.\|.FASS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	847	GFAS.\|.SSSG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	847	GFAS.\|.SSSG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	848	FASS.\|.SSGK	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	848	FASS.\|.SSGK	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)