O15355: Protein phosphatase 1G

General Information

Protein names	- Protein phosphatase 1G - 3.1.3.16 - Protein phosphatase 1C - Protein phosphatase 2C isoform gamma - PP2C-gamma - Protein phosphatase magnesium-dependent 1 gamma
Gene names	PPM1G
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O15355

21 N-termini

14 C-termini

14 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGAYLSQPNT VKCSGDGVGA PRLPLPYGFS AMQGWRVSME DAHNCIPELD SETAMFSVYD
        70         80         90        100        110        120
GHGGEEVALY CAKYLPDIIK DQKAYKEGKL QKALEDAFLA IDAKLTTEEV IKELAQIAGR
       130        140        150        160        170        180
PTEDEDEKEK VADEDDVDNE EAALLHEEAT MTIEELLTRY GQNCHKGPPH SKSGGGTGEE
       190        200        210        220        230        240
PGSQGLNGEA GPEDSTRETP SQENGPTAKA YTGFSSNSER GTEAGQVGEP GIPTGEAGPS
       250        260        270        280        290        300
CSSASDKLPR VAKSKFFEDS EDESDEAEEE EEDSEECSEE EDGYSSEEAE NEEDEDDTEE
       310        320        330        340        350        360
AEEDDEEEEE EMMVPGMEGK EEPGSDSGTT AVVALIRGKQ LIVANAGDSR CVVSEAGKAL
       370        380        390        400        410        420
DMSYDHKPED EVELARIKNA GGKVTMDGRV NGGLNLSRAI GDHFYKRNKN LPPEEQMISA
       430        440        450        460        470        480
LPDIKVLTLT DDHEFMVIAC DGIWNVMSSQ EVVDFIQSKI SQRDENGELR LLSSIVEELL
       490        500        510        520        530        540
DQCLAPDTSG DGTGCDNMTC IIICFKPRNT AELQPESGKR KLEEVLSTEG AEENGNSDKK

KKAKRD

Isoforms

Sequence View

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O15355-1-unknown	MGAYLS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O15355-33-unknown	QGWRVS...	33	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13721
O15355-116-unknown	QIAGRP...	116	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5143
O15355-116-unknown	QIAGRP...	116	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7014
O15355-117-unknown	IAGRPT...	117	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3266
O15355-119-unknown	GRPTED...	119	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5144
O15355-142-unknown	AALLHE...	142		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O15355-142-	AALLHE...	142		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
O15355-148-unknown	EATMTI...	148	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10709
O15355-155-unknown	ELLTRY...	155	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
O15355-167-	GPPHSK...	167		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
O15355-210-	AYTGFS...	210		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O15355-218-	SERGTE...	218		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O15355-243-unknown	SASDKL...	243	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7015
O15355-327-unknown	SGTTAV...	327	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10710
O15355-350-unknown	RCVVSE...	350	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10711
O15355-362-unknown	MSYDHK...	362	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13722
O15355-363-	SYDHKP...	363		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O15355-364-unknown	YDHKPE...	364	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13723
O15355-366-unknown	HKPEDE...	366	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5145
O15355-387-unknown	DGRVNG...	387	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13724
O15355-388-unknown	GRVNGG...	388	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10712

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GFSAMQ	32	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13721
...IKELAQ	115	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5143
...IKELAQ	115	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7014
...KELAQI	116	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3266
...LAQIAG	118	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5144
...ALLHEE	147	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10709
...GPSCSS	242	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7015
...EPGSDS	326	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10710
...NAGDSR	349	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10711
...GKALDM	361	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13722
...ALDMSY	363	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13723
...DMSYDH	365	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5145
...GKVTMD	386	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13724
...KVTMDG	387	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10712
...KAKRD	546	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	32	SAMQ.\|.QGWR	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CATL1_HUMAN	115	ELAQ.\|.QIAG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	115	ELAQ.\|.QIAG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	116	LAQI.\|.IAGR	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	118	QIAG.\|.GRPT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	147	LHEE.\|.EATM	inferred from experiment	unknown	MEROPS		Merops GRAB_HUMAN -> PPM1G_HUMAN @147
GRAB_HUMAN	147	LHEE.\|.EATM	inferred from experiment	unknown	MEROPS	Gevaert K	Plasman K et al.:Probing the efficiency of prote... (S01.010)	21048194,
CATS_HUMAN	242	SCSS.\|.SASD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	326	GSDS.\|.SGTT	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	349	GDSR.\|.RCVV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAM_HUMAN	361	ALDM.\|.MSYD	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	363	DMSY.\|.YDHK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CATL1_HUMAN	365	SYDH.\|.HKPE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAM_HUMAN	386	VTMD.\|.DGRV	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	387	TMDG.\|.GRVN	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

TopFIND

O15355: Protein phosphatase 1G

General Information

21

N-termini

14

C-termini

14

Cleavages

0

Substrates

Sequence

Isoforms

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Protein Neighborhood

Domains & Features

21 N-termini - 14 C-termini - 14 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates