Q15369: Elongin-C

General Information

Protein names	- Elongin-C - EloC - Elongin 15 kDa subunit - RNA polymerase II transcription factor SIII subunit C - SIII p15 - Transcription elongation factor B polypeptide 1
Gene names	TCEB1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15369

5 N-termini

4 C-termini

4 Cleavages

0 Substrates

Sequence

10 20 30 40 50 60
MDGEEKTYGG CEGPDAMYVK LISSDGHEFI VKREHALTSG TIKAMLSGPG QFAENETNEV
70 80 90 100 110
NFREIPSHVL SKVCMYFTYK VRYTNSSTEI PEFPIAPEIA LELLMAANFL DC

Isoforms

- Isoform 2 of Transcription elongation factor B polypeptide 1 - Isoform 2 of Elongin-C

Sequence View

        10         20         30         40         50         60
MDGEEKTYGG CEGPDAMYVK LISSDGHEFI VKREHALTSG TIKAMLSGPG QFAENETNEV
        70         80         90        100        110
NFREIPSHVL SKVCMYFTYK VRYTNSSTEI PEFPIAPEIA LELLMAANFL DC         10         20         30         40         50         60
MDGEEKTYGG CEGPDAMYVK LISSDGHEFI VKREHALTSG TIKAMLSGPG QFAENETNEV
        70         80         90        100        110
NFREIPSHVL SKVCMYFTYK VRYTNSSTEI PEFPIAPEIA LELLMAANFL DC

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q15369-1-unknown	MDGEEK...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q15369-10-unknown	GCEGPD...	10	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6470
Q15369-17-unknown	MYVKLI...	17	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt73831
Q15369-24-unknown	SDGHEF...	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6471
Q15369-24-unknown	SDGHEF...	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7864
Q15369-24-unknown	SDGHEF...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195337
Q15369-48-unknown	GPGQFA...	48	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6472
Q15369-48-unknown	GPGQFA...	48	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt137689

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EKTYGG	9	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6470
...VKLISS	23	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6471
...VKLISS	23	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7864
...KAMLSG	47	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6472
...KAMLSG	47	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120686
...NFLDC	112	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...NFLDC	112	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt69449

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	9	TYGG.\|.GCEG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	23	LISS.\|.SDGH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	23	LISS.\|.SDGH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	47	MLSG.\|.GPGQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)