P51610: Host cell factor 1
Protein names | - Host cell factor 1 - HCF - HCF-1 - C1 factor - CFF - VCAF - VP16 accessory protein - HCF N-terminal chain 1 - HCF N-terminal chain 2 - HCF N-terminal chain 3 - HCF N-terminal chain 4 - HCF N-terminal chain 5 - HCF N-terminal chain 6 - HCF C-terminal chain 1 - HCF C-terminal chain 2 - HCF C-terminal chain 3 - HCF C-terminal chain 4 - HCF C-terminal chain 5 - HCF C-terminal chain 6 |
---|---|
Gene names | HCFC1 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P51610 |
34
N-termini
13
C-termini
7
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MASAVSPANL PAVLLQPRWK RVVGWSGPVP RPRHGHRAVA IKELIVVFGG GNEGIVDELH
70 80 90 100 110 120
VYNTATNQWF IPAVRGDIPP GCAAYGFVCD GTRLLVFGGM VEYGKYSNDL YELQASRWEW
130 140 150 160 170 180
KRLKAKTPKN GPPPCPRLGH SFSLVGNKCY LFGGLANDSE DPKNNIPRYL NDLYILELRP
190 200 210 220 230 240
GSGVVAWDIP ITYGVLPPPR ESHTAVVYTE KDNKKSKLVI YGGMSGCRLG DLWTLDIDTL
250 260 270 280 290 300
TWNKPSLSGV APLPRSLHSA TTIGNKMYVF GGWVPLVMDD VKVATHEKEW KCTNTLACLN
310 320 330 340 350 360
LDTMAWETIL MDTLEDNIPR ARAGHCAVAI NTRLYIWSGR DGYRKAWNNQ VCCKDLWYLE
370 380 390 400 410 420
TEKPPPPARV QLVRANTNSL EVSWGAVATA DSYLLQLQKY DIPATAATAT SPTPNPVPSV
430 440 450 460 470 480
PANPPKSPAP AAAAPAVQPL TQVGITLLPQ AAPAPPTTTT IQVLPTVPGS SISVPTAART
490 500 510 520 530 540
QGVPAVLKVT GPQATTGTPL VTMRPASQAG KAPVTVTSLP AGVRMVVPTQ SAQGTVIGSS
550 560 570 580 590 600
PQMSGMAALA AAAAATQKIP PSSAPTVLSV PAGTTIVKTM AVTPGTTTLP ATVKVASSPV
610 620 630 640 650 660
MVSNPATRML KTAAAQVGTS VSSATNTSTR PIITVHKSGT VTVAQQAQVV TTVVGGVTKT
670 680 690 700 710 720
ITLVKSPISV PGGSALISNL GKVMSVVQTK PVQTSAVTGQ ASTGPVTQII QTKGPLPAGT
730 740 750 760 770 780
ILKLVTSADG KPTTIITTTQ ASGAGTKPTI LGISSVSPST TKPGTTTIIK TIPMSAIITQ
790 800 810 820 830 840
AGATGVTSSP GIKSPITIIT TKVMTSGTGA PAKIITAVPK IATGHGQQGV TQVVLKGAPG
850 860 870 880 890 900
QPGTILRTVP MGGVRLVTPV TVSAVKPAVT TLVVKGTTGV TTLGTVTGTV STSLAGAGGH
910 920 930 940 950 960
STSASLATPI TTLGTIATLS SQVINPTAIT VSAAQTTLTA AGGLTTPTIT MQPVSQPTQV
970 980 990 1000 1010 1020
TLITAPSGVE AQPVHDLPVS ILASPTTEQP TATVTIADSG QGDVQPGTVT LVCSNPPCET
1030 1040 1050 1060 1070 1080
HETGTTNTAT TTVVANLGGH PQPTQVQFVC DRQEAAASLV TSTVGQQNGS VVRVCSNPPC
1090 1100 1110 1120 1130 1140
ETHETGTTNT ATTATSNMAG QHGCSNPPCE THETGTTNTA TTAMSSVGAN HQRDARRACA
1150 1160 1170 1180 1190 1200
AGTPAVIRIS VATGALEAAQ GSKSQCQTRQ TSATSTTMTV MATGAPCSAG PLLGPSMARE
1210 1220 1230 1240 1250 1260
PGGRSPAFVQ LAPLSSKVRL SSPSIKDLPA GRHSHAVSTA AMTRSSVGAG EPRMAPVCES
1270 1280 1290 1300 1310 1320
LQGGSPSTTV TVTALEALLC PSATVTQVCS NPPCETHETG TTNTATTSNA GSAQRVCSNP
1330 1340 1350 1360 1370 1380
PCETHETGTT HTATTATSNG GTGQPEGGQQ PPAGRPCETH QTTSTGTTMS VSVGALLPDA
1390 1400 1410 1420 1430 1440
TSSHRTVESG LEVAAAPSVT PQAGTALLAP FPTQRVCSNP PCETHETGTT HTATTVTSNM
1450 1460 1470 1480 1490 1500
SSNQDPPPAA SDQGEVESTQ GDSVNITSSS AITTTVSSTL TRAVTTVTQS TPVPGPSVPP
1510 1520 1530 1540 1550 1560
PEELQVSPGP RQQLPPRQLL QSASTALMGE SAEVLSASQT PELPAAVDLS STGEPSSGQE
1570 1580 1590 1600 1610 1620
SAGSAVVATV VVQPPPPTQS EVDQLSLPQE LMAEAQAGTT TLMVTGLTPE ELAVTAAAEA
1630 1640 1650 1660 1670 1680
AAQAAATEEA QALAIQAVLQ AAQQAVMGTG EPMDTSEAAA TVTQAELGHL SAEGQEGQAT
1690 1700 1710 1720 1730 1740
TIPIVLTQQE LAALVQQQQL QEAQAQQQHH HLPTEALAPA DSLNDPAIES NCLNELAGTV
1750 1760 1770 1780 1790 1800
PSTVALLPST ATESLAPSNT FVAPQPVVVA SPAKLQAAAT LTEVANGIES LGVKPDLPPP
1810 1820 1830 1840 1850 1860
PSKAPMKKEN QWFDVGVIKG TNVMVTHYFL PPDDAVPSDD DLGTVPDYNQ LKKQELQPGT
1870 1880 1890 1900 1910 1920
AYKFRVAGIN ACGRGPFSEI SAFKTCLPGF PGAPCAIKIS KSPDGAHLTW EPPSVTSGKI
1930 1940 1950 1960 1970 1980
IEYSVYLAIQ SSQAGGELKS STPAQLAFMR VYCGPSPSCL VQSSSLSNAH IDYTTKPAII
1990 2000 2010 2020 2030
FRIAARNEKG YGPATQVRWL QETSKDSSGT KPANKRPMSS PEMKSAPKKS KADGQ
Isoforms
- Isoform 2 of Host cell factor 1 - Isoform 3 of Host cell factor 1 - Isoform 4 of Host cell factor 1Sequence View
10 20 30 40 50 60
MASAVSPANL PAVLLQPRWK RVVGWSGPVP RPRHGHRAVA IKELIVVFGG GNEGIVDELH
70 80 90 100 110 120
VYNTATNQWF IPAVRGDIPP GCAAYGFVCD GTRLLVFGGM VEYGKYSNDL YELQASRWEW
130 140 150 160 170 180
KRLKAKTPKN GPPPCPRLGH SFSLVGNKCY LFGGLANDSE DPKNNIPRYL NDLYILELRP
190 200 210 220 230 240
GSGVVAWDIP ITYGVLPPPR ESHTAVVYTE KDNKKSKLVI YGGMSGCRLG DLWTLDIDTL
250 260 270 280 290 300
TWNKPSLSGV APLPRSLHSA TTIGNKMYVF GGWVPLVMDD VKVATHEKEW KCTNTLACLN
310 320 330 340 350 360
LDTMAWETIL MDTLEDNIPR ARAGHCAVAI NTRLYIWSGR DGYRKAWNNQ VCCKDLWYLE
370 380 390 400 410 420
TEKPPPPARV QLVRANTNSL EVSWGAVATA DSYLLQLQKY DIPATAATAT SPTPNPVPSV
430 440 450 460 470 480
PANPPKSPAP AAAAPAVQPL TQVGITLLPQ AAPAPPTTTT IQVLPTVPGS SISVPTAART
490 500 510 520 530 540
QGVPAVLKVT GPQATTGTPL VTMRPASQAG KAPVTVTSLP AGVRMVVPTQ SAQGTVIGSS
550 560 570 580 590 600
PQMSGMAALA AAAAATQKIP PSSAPTVLSV PAGTTIVKTM AVTPGTTTLP ATVKVASSPV
610 620 630 640 650 660
MVSNPATRML KTAAAQVGTS VSSATNTSTR PIITVHKSGT VTVAQQAQVV TTVVGGVTKT
670 680 690 700 710 720
ITLVKSPISV PGGSALISNL GKVMSVVQTK PVQTSAVTGQ ASTGPVTQII QTKGPLPAGT
730 740 750 760 770 780
ILKLVTSADG KPTTIITTTQ ASGAGTKPTI LGISSVSPST TKPGTTTIIK TIPMSAIITQ
790 800 810 820 830 840
AGATGVTSSP GIKSPITIIT TKVMTSGTGA PAKIITAVPK IATGHGQQGV TQVVLKGAPG
850 860 870 880 890 900
QPGTILRTVP MGGVRLVTPV TVSAVKPAVT TLVVKGTTGV TTLGTVTGTV STSLAGAGGH
910 920 930 940 950 960
STSASLATPI TTLGTIATLS SQVINPTAIT VSAAQTTLTA AGGLTTPTIT MQPVSQPTQV
970 980 990 1000 1010 1020
TLITAPSGVE AQPVHDLPVS ILASPTTEQP TATVTIADSG QGDVQPGTVT LVCSNPPCET
1030 1040 1050 1060 1070 1080
HETGTTNTAT TTVVANLGGH PQPTQVQFVC DRQEAAASLV TSTVGQQNGS VVRVCSNPPC
1090 1100 1110 1120 1130 1140
ETHETGTTNT ATTATSNMAG QHGCSNPPCE THETGTTNTA TTAMSSVGAN HQRDARRACA
1150 1160 1170 1180 1190 1200
AGTPAVIRIS VATGALEAAQ GSKSQCQTRQ TSATSTTMTV MATGAPCSAG PLLGPSMARE
1210 1220 1230 1240 1250 1260
PGGRSPAFVQ LAPLSSKVRL SSPSIKDLPA GRHSHAVSTA AMTRSSVGAG EPRMAPVCES
1270 1280 1290 1300 1310 1320
LQGGSPSTTV TVTALEALLC PSATVTQVCS NPPCETHETG TTNTATTSNA GSAQRVCSNP
1330 1340 1350 1360 1370 1380
PCETHETGTT HTATTATSNG GTGQPEGGQQ PPAGRPCETH QTTSTGTTMS VSVGALLPDA
1390 1400 1410 1420 1430 1440
TSSHRTVESG LEVAAAPSVT PQAGTALLAP FPTQRVCSNP PCETHETGTT HTATTVTSNM
1450 1460 1470 1480 1490 1500
SSNQDPPPAA SDQGEVESTQ GDSVNITSSS AITTTVSSTL TRAVTTVTQS TPVPGPSVPP
1510 1520 1530 1540 1550 1560
PEELQVSPGP RQQLPPRQLL QSASTALMGE SAEVLSASQT PELPAAVDLS STGEPSSGQE
1570 1580 1590 1600 1610 1620
SAGSAVVATV VVQPPPPTQS EVDQLSLPQE LMAEAQAGTT TLMVTGLTPE ELAVTAAAEA
1630 1640 1650 1660 1670 1680
AAQAAATEEA QALAIQAVLQ AAQQAVMGTG EPMDTSEAAA TVTQAELGHL SAEGQEGQAT
1690 1700 1710 1720 1730 1740
TIPIVLTQQE LAALVQQQQL QEAQAQQQHH HLPTEALAPA DSLNDPAIES NCLNELAGTV
1750 1760 1770 1780 1790 1800
PSTVALLPST ATESLAPSNT FVAPQPVVVA SPAKLQAAAT LTEVANGIES LGVKPDLPPP
1810 1820 1830 1840 1850 1860
PSKAPMKKEN QWFDVGVIKG TNVMVTHYFL PPDDAVPSDD DLGTVPDYNQ LKKQELQPGT
1870 1880 1890 1900 1910 1920
AYKFRVAGIN ACGRGPFSEI SAFKTCLPGF PGAPCAIKIS KSPDGAHLTW EPPSVTSGKI
1930 1940 1950 1960 1970 1980
IEYSVYLAIQ SSQAGGELKS STPAQLAFMR VYCGPSPSCL VQSSSLSNAH IDYTTKPAII
1990 2000 2010 2020 2030
FRIAARNEKG YGPATQVRWL QETSKDSSGT KPANKRPMSS PEMKSAPKKS KADGQ
10 20 30 40 50 60
MASAVSPANL PAVLLQPRWK RVVGWSGPVP RPRHGHRAVA IKELIVVFGG GNEGIVDELH
70 80 90 100 110 120
VYNTATNQWF IPAVRGDIPP GCAAYGFVCD GTRLLVFGGM VEYGKYSNDL YELQASRWEW
130 140 150 160 170 180
KRLKAKTPKN GPPPCPRLGH SFSLVGNKCY LFGGLANDSE DPKNNIPRYL NDLYILELRP
190 200 210 220 230 240
GSGVVAWDIP ITYGVLPPPR ESHTAVVYTE KDNKKSKLVI YGGMSGCRLG DLWTLDIDTL
250 260 270 280 290 300
TWNKPSLSGV APLPRSLHSA TTIGNKMYVF GGWVPLVMDD VKVATHEKEW KCTNTLACLN
310 320 330 340 350 360
LDTMAWETIL MDTLEDNIPR ARAGHCAVAI NTRLYIWSGR DGYRKAWNNQ VCCKDLWYLE
370 380 390 400 410 420
TEKPPPPARV QLVRANTNSL EVSWGAVATA DSYLLQLQKY DIPATAATAT SPTPNPVPSV
430 440 450 460 470 480
PANPPKSPAP AAAAPAVQPL TQVGITLLPQ AAPAPPTTTT IQVLPTVPGS SISVPTAART
490 500 510 520 530 540
QGVPAVLKVT GPQATTGTPL VTMRPASQAG KAPVTVTSLP AGVRMVVPTQ SAQGTVIGSS
550 560 570 580 590 600
PQMSGMAALA AAAAATQKIP PSSAPTVLSV PAGTTIVKTM AVTPGTTTLP ATVKVASSPV
610 620 630 640 650 660
MVSNPATRML KTAAAQVGTS VSSATNTSTR PIITVHKSGT VTVAQQAQVV TTVVGGVTKT
670 680 690 700 710 720
ITLVKSPISV PGGSALISNL GKVMSVVQTK PVQTSAVTGQ ASTGPVTQII QTKGPLPAGT
730 740 750 760 770 780
ILKLVTSADG KPTTIITTTQ ASGAGTKPTI LGISSVSPST TKPGTTTIIK TIPMSAIITQ
790 800 810 820 830 840
AGATGVTSSP GIKSPITIIT TKVMTSGTGA PAKIITAVPK IATGHGQQGV TQVVLKGAPG
850 860 870 880 890 900
QPGTILRTVP MGGVRLVTPV TVSAVKPAVT TLVVKGTTGV TTLGTVTGTV STSLAGAGGH
910 920 930 940 950 960
STSASLATPI TTLGTIATLS SQVINPTAIT VSAAQTTLTA AGGLTTPTIT MQPVSQPTQV
970 980 990 1000 1010 1020
TLITAPSGVE AQPVHDLPVS ILASPTTEQP TATVTIADSG QGDVQPGTVT LVCSNPPCET
1030 1040 1050 1060 1070 1080
HETGTTNTAT TTVVANLGGH PQPTQVQFVC DRQEAAASLV TSTVGQQNGS VVRVCSNPPC
1090 1100 1110 1120 1130 1140
ETHETGTTNT ATTATSNMAG QHGCSNPPCE THETGTTNTA TTAMSSVGAN HQRDARRACA
1150 1160 1170 1180 1190 1200
AGTPAVIRIS VATGALEAAQ GSKSQCQTRQ TSATSTTMTV MATGAPCSAG PLLGPSMARE
1210 1220 1230 1240 1250 1260
PGGRSPAFVQ LAPLSSKVRL SSPSIKDLPA GRHSHAVSTA AMTRSSVGAG EPRMAPVCES
1270 1280 1290 1300 1310 1320
LQGGSPSTTV TVTALEALLC PSATVTQVCS NPPCETHETG TTNTATTSNA GSAQRVCSNP
1330 1340 1350 1360 1370 1380
PCETHETGTT HTATTATSNG GTGQPEGGQQ PPAGRPCETH QTTSTGTTMS VSVGALLPDA
1390 1400 1410 1420 1430 1440
TSSHRTVESG LEVAAAPSVT PQAGTALLAP FPTQRVCSNP PCETHETGTT HTATTVTSNM
1450 1460 1470 1480 1490 1500
SSNQDPPPAA SDQGEVESTQ GDSVNITSSS AITTTVSSTL TRAVTTVTQS TPVPGPSVPP
1510 1520 1530 1540 1550 1560
PEELQVSPGP RQQLPPRQLL QSASTALMGE SAEVLSASQT PELPAAVDLS STGEPSSGQE
1570 1580 1590 1600 1610 1620
SAGSAVVATV VVQPPPPTQS EVDQLSLPQE LMAEAQAGTT TLMVTGLTPE ELAVTAAAEA
1630 1640 1650 1660 1670 1680
AAQAAATEEA QALAIQAVLQ AAQQAVMGTG EPMDTSEAAA TVTQAELGHL SAEGQEGQAT
1690 1700 1710 1720 1730 1740
TIPIVLTQQE LAALVQQQQL QEAQAQQQHH HLPTEALAPA DSLNDPAIES NCLNELAGTV
1750 1760 1770 1780 1790 1800
PSTVALLPST ATESLAPSNT FVAPQPVVVA SPAKLQAAAT LTEVANGIES LGVKPDLPPP
1810 1820 1830 1840 1850 1860
PSKAPMKKEN QWFDVGVIKG TNVMVTHYFL PPDDAVPSDD DLGTVPDYNQ LKKQELQPGT
1870 1880 1890 1900 1910 1920
AYKFRVAGIN ACGRGPFSEI SAFKTCLPGF PGAPCAIKIS KSPDGAHLTW EPPSVTSGKI
1930 1940 1950 1960 1970 1980
IEYSVYLAIQ SSQAGGELKS STPAQLAFMR VYCGPSPSCL VQSSSLSNAH IDYTTKPAII
1990 2000 2010 2020 2030
FRIAARNEKG YGPATQVRWL QETSKDSSGT KPANKRPMSS PEMKSAPKKS KADGQ
10 20 30 40 50 60
MASAVSPANL PAVLLQPRWK RVVGWSGPVP RPRHGHRAVA IKELIVVFGG GNEGIVDELH
70 80 90 100 110 120
VYNTATNQWF IPAVRGDIPP GCAAYGFVCD GTRLLVFGGM VEYGKYSNDL YELQASRWEW
130 140 150 160 170 180
KRLKAKTPKN GPPPCPRLGH SFSLVGNKCY LFGGLANDSE DPKNNIPRYL NDLYILELRP
190 200 210 220 230 240
GSGVVAWDIP ITYGVLPPPR ESHTAVVYTE KDNKKSKLVI YGGMSGCRLG DLWTLDIDTL
250 260 270 280 290 300
TWNKPSLSGV APLPRSLHSA TTIGNKMYVF GGWVPLVMDD VKVATHEKEW KCTNTLACLN
310 320 330 340 350 360
LDTMAWETIL MDTLEDNIPR ARAGHCAVAI NTRLYIWSGR DGYRKAWNNQ VCCKDLWYLE
370 380 390 400 410 420
TEKPPPPARV QLVRANTNSL EVSWGAVATA DSYLLQLQKY DIPATAATAT SPTPNPVPSV
430 440 450 460 470 480
PANPPKSPAP AAAAPAVQPL TQVGITLLPQ AAPAPPTTTT IQVLPTVPGS SISVPTAART
490 500 510 520 530 540
QGVPAVLKVT GPQATTGTPL VTMRPASQAG KAPVTVTSLP AGVRMVVPTQ SAQGTVIGSS
550 560 570 580 590 600
PQMSGMAALA AAAAATQKIP PSSAPTVLSV PAGTTIVKTM AVTPGTTTLP ATVKVASSPV
610 620 630 640 650 660
MVSNPATRML KTAAAQVGTS VSSATNTSTR PIITVHKSGT VTVAQQAQVV TTVVGGVTKT
670 680 690 700 710 720
ITLVKSPISV PGGSALISNL GKVMSVVQTK PVQTSAVTGQ ASTGPVTQII QTKGPLPAGT
730 740 750 760 770 780
ILKLVTSADG KPTTIITTTQ ASGAGTKPTI LGISSVSPST TKPGTTTIIK TIPMSAIITQ
790 800 810 820 830 840
AGATGVTSSP GIKSPITIIT TKVMTSGTGA PAKIITAVPK IATGHGQQGV TQVVLKGAPG
850 860 870 880 890 900
QPGTILRTVP MGGVRLVTPV TVSAVKPAVT TLVVKGTTGV TTLGTVTGTV STSLAGAGGH
910 920 930 940 950 960
STSASLATPI TTLGTIATLS SQVINPTAIT VSAAQTTLTA AGGLTTPTIT MQPVSQPTQV
970 980 990 1000 1010 1020
TLITAPSGVE AQPVHDLPVS ILASPTTEQP TATVTIADSG QGDVQPGTVT LVCSNPPCET
1030 1040 1050 1060 1070 1080
HETGTTNTAT TTVVANLGGH PQPTQVQFVC DRQEAAASLV TSTVGQQNGS VVRVCSNPPC
1090 1100 1110 1120 1130 1140
ETHETGTTNT ATTATSNMAG QHGCSNPPCE THETGTTNTA TTAMSSVGAN HQRDARRACA
1150 1160 1170 1180 1190 1200
AGTPAVIRIS VATGALEAAQ GSKSQCQTRQ TSATSTTMTV MATGAPCSAG PLLGPSMARE
1210 1220 1230 1240 1250 1260
PGGRSPAFVQ LAPLSSKVRL SSPSIKDLPA GRHSHAVSTA AMTRSSVGAG EPRMAPVCES
1270 1280 1290 1300 1310 1320
LQGGSPSTTV TVTALEALLC PSATVTQVCS NPPCETHETG TTNTATTSNA GSAQRVCSNP
1330 1340 1350 1360 1370 1380
PCETHETGTT HTATTATSNG GTGQPEGGQQ PPAGRPCETH QTTSTGTTMS VSVGALLPDA
1390 1400 1410 1420 1430 1440
TSSHRTVESG LEVAAAPSVT PQAGTALLAP FPTQRVCSNP PCETHETGTT HTATTVTSNM
1450 1460 1470 1480 1490 1500
SSNQDPPPAA SDQGEVESTQ GDSVNITSSS AITTTVSSTL TRAVTTVTQS TPVPGPSVPP
1510 1520 1530 1540 1550 1560
PEELQVSPGP RQQLPPRQLL QSASTALMGE SAEVLSASQT PELPAAVDLS STGEPSSGQE
1570 1580 1590 1600 1610 1620
SAGSAVVATV VVQPPPPTQS EVDQLSLPQE LMAEAQAGTT TLMVTGLTPE ELAVTAAAEA
1630 1640 1650 1660 1670 1680
AAQAAATEEA QALAIQAVLQ AAQQAVMGTG EPMDTSEAAA TVTQAELGHL SAEGQEGQAT
1690 1700 1710 1720 1730 1740
TIPIVLTQQE LAALVQQQQL QEAQAQQQHH HLPTEALAPA DSLNDPAIES NCLNELAGTV
1750 1760 1770 1780 1790 1800
PSTVALLPST ATESLAPSNT FVAPQPVVVA SPAKLQAAAT LTEVANGIES LGVKPDLPPP
1810 1820 1830 1840 1850 1860
PSKAPMKKEN QWFDVGVIKG TNVMVTHYFL PPDDAVPSDD DLGTVPDYNQ LKKQELQPGT
1870 1880 1890 1900 1910 1920
AYKFRVAGIN ACGRGPFSEI SAFKTCLPGF PGAPCAIKIS KSPDGAHLTW EPPSVTSGKI
1930 1940 1950 1960 1970 1980
IEYSVYLAIQ SSQAGGELKS STPAQLAFMR VYCGPSPSCL VQSSSLSNAH IDYTTKPAII
1990 2000 2010 2020 2030
FRIAARNEKG YGPATQVRWL QETSKDSSGT KPANKRPMSS PEMKSAPKKS KADGQ
Protein Neighborhood
Domains & Features
34 N-termini - 13 C-termini - 7 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P51610-1-unknown | MASAVS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt76782 | |||
P51610-1-unknown | MASAVS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt76783 | |||
P51610-1-unknown | MASAVS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt76784 | |||
P51610-2-unknown | MASAVS... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P51610-2-Acetylation | ASAVSP... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
P51610-2-Acetylation | ASAVSP... | 2 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
P51610-2-Acetylation | ASAVSP... | 2 | acetylation- | other | CNRS/ISV | Large_scale_NTA_Human | |||
P51610-2-Acetylation | ASAVSP... | 2 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | ||
P51610-2-Acetylation | ASAVSP... | 2 | acetylation- | N-TAILS | Overall Laboratory | Lange_Huesgen_et_al-RBC | |||
P51610-2-Acetylation | ASAVSP... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110755 | ||
P51610-2-Acetylation | ASAVSP... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110756 | ||
P51610-2-Acetylation | ASAVSP... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110757 | ||
P51610-152-unknown | FGGLAN... | 152 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3818 | |||
P51610-152-unknown | FGGLAN... | 152 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144833 | |||
P51610-152-unknown | FGGLAN... | 152 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144834 | |||
P51610-152-unknown | FGGLAN... | 152 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144835 | |||
P51610-256-unknown | SLHSAT... | 256 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt172143 | |||
P51610-256-unknown | SLHSAT... | 256 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt172144 | |||
P51610-256-unknown | SLHSAT... | 256 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt172145 | |||
P51610-256- | SLHSAT... | 256 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P51610-361-unknown | TEKPPP... | 361 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5956 | |||
P51610-361-unknown | TEKPPP... | 361 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt151194 | |||
P51610-361-unknown | TEKPPP... | 361 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt151195 | |||
P51610-361-unknown | TEKPPP... | 361 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt151196 | |||
P51610-569-unknown | SVPAGT... | 569 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt168703 | |||
P51610-569-unknown | SVPAGT... | 569 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt168702 | |||
P51610-569- | SVPAGT... | 569 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P51610-755-unknown | SVSPST... | 755 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5960 | |||
P51610-755-unknown | SVSPST... | 755 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt155709 | |||
P51610-755-unknown | SVSPST... | 755 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156285 | |||
P51610-803- | VMTSGT... | 803 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P51610-803-unknown | VMTSGT... | 803 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P51610-803-unknown | VMTSGT... | 803 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159705 | |||
P51610-803-unknown | VMTSGT... | 803 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159704 | |||
P51610-837- | GAPGQP... | 837 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P51610-837-unknown | GAPGQP... | 837 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P51610-837-unknown | GAPGQP... | 837 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159702 | |||
P51610-837-unknown | GAPGQP... | 837 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159701 | |||
P51610-1020-unknown | THETGT... | 1020 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P51610-1020-unknown | THETGT... | 1020 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116445 | |||
P51610-1020-unknown | THETGT... | 1020 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116444 | |||
P51610-1082-unknown | THETGT... | 1082 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P51610-1082-unknown | THETGT... | 1082 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116447 | |||
P51610-1082-unknown | THETGT... | 1082 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116446 | |||
P51610-1111-unknown | THETGT... | 1111 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P51610-1111-unknown | THETGT... | 1111 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116465 | |||
P51610-1111-unknown | THETGT... | 1111 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116464 | |||
P51610-1111- | THETGT... | 1111 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P51610-1111- | THETGT... | 1111 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P51610-1111- | THETGT... | 1111 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P51610-1111- | THETGT... | 1111 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P51610-1296-unknown | THETGT... | 1296 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P51610-1296-unknown | THETGT... | 1296 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P51610-1296-unknown | THETGT... | 1296 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P51610-1296-unknown | THETGT... | 1296 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116479 | |||
P51610-1296-unknown | THETGT... | 1296 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116478 | |||
P51610-1296- | THETGT... | 1296 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
P51610-1296- | THETGT... | 1296 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
P51610-1296- | THETGT... | 1296 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P51610-1296- | THETGT... | 1296 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P51610-1296- | THETGT... | 1296 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
P51610-1296- | THETGT... | 1296 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P51610-1296- | THETGT... | 1296 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P51610-1296- | THETGT... | 1296 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P51610-1296- | THETGT... | 1296 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
P51610-1296- | THETGT... | 1296 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P51610-1324-unknown | THETGT... | 1324 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P51610-1324-unknown | THETGT... | 1324 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116487 | |||
P51610-1324-unknown | THETGT... | 1324 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116486 | |||
P51610-1370-unknown | SVSVGA... | 1370 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt166656 | |||
P51610-1370-unknown | SVSVGA... | 1370 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt166655 | |||
P51610-1370- | SVSVGA... | 1370 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P51610-1370- | SVSVGA... | 1370 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P51610-1370- | SVSVGA... | 1370 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P51610-1370- | SVSVGA... | 1370 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
P51610-1370- | SVSVGA... | 1370 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P51610-1370- | SVSVGA... | 1370 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P51610-1372- | SVGALL... | 1372 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P51610-1372-unknown | SVGALL... | 1372 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173133 | |||
P51610-1372-unknown | SVGALL... | 1372 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173132 | |||
P51610-1375-unknown | ALLPDA... | 1375 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5963 | |||
P51610-1375-unknown | ALLPDA... | 1375 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157907 | |||
P51610-1375-unknown | ALLPDA... | 1375 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157994 | |||
P51610-1375- | ALLPDA... | 1375 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P51610-1424-unknown | THETGT... | 1424 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P51610-1424-unknown | THETGT... | 1424 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116489 | |||
P51610-1424-unknown | THETGT... | 1424 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116488 | |||
P51610-1490-unknown | STPVPG... | 1490 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt166653 | |||
P51610-1490- | STPVPG... | 1490 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P51610-1490- | STPVPG... | 1490 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
P51610-1490- | STPVPG... | 1490 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P51610-1490- | STPVPG... | 1490 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P51610-1490- | STPVPG... | 1490 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P51610-1490- | STPVPG... | 1490 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P51610-1787-unknown | GIESLG... | 1787 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175221 | |||
P51610-1787-unknown | GIESLG... | 1787 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175220 | |||
P51610-1787- | GIESLG... | 1787 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P51610-1793-unknown | VKPDLP... | 1793 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5966 | |||
P51610-1793-unknown | VKPDLP... | 1793 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7529 | |||
P51610-1793-unknown | VKPDLP... | 1793 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158454 | |||
P51610-1793-unknown | VKPDLP... | 1793 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158599 | |||
P51610-1830-unknown | LPPDDA... | 1830 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5969 | |||
P51610-1830-unknown | LPPDDA... | 1830 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158510 | |||
P51610-1830-unknown | LPPDDA... | 1830 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158644 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...NKCYLF | 151 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3818 | |||
...NKCYLF | 151 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt128109 | |||
...NKCYLF | 151 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt128110 | |||
...NKCYLF | 151 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt128111 | |||
...LWYLET | 360 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5956 | |||
...LWYLET | 360 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt134596 | |||
...LWYLET | 360 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt134597 | |||
...LWYLET | 360 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt134598 | |||
...ILGISS | 754 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5960 | |||
...ILGISS | 754 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139155 | |||
...ILGISS | 754 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139757 | |||
...NPPCET | 1019 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...NPPCET | 1019 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93617 | |||
...NPPCET | 1019 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93616 | |||
...NPPCET | 1081 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...NPPCET | 1081 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93642 | |||
...NPPCET | 1081 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93641 | |||
...NPPCET | 1110 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...NPPCET | 1110 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93661 | |||
...NPPCET | 1110 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93660 | |||
...NPPCET | 1295 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...NPPCET | 1295 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93724 | |||
...NPPCET | 1295 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93723 | |||
...NPPCET | 1323 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...NPPCET | 1323 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93732 | |||
...NPPCET | 1323 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93731 | |||
...SVSVGA | 1374 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5963 | |||
...SVSVGA | 1374 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141402 | |||
...SVSVGA | 1374 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141489 | |||
...NPPCET | 1423 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...NPPCET | 1423 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93750 | |||
...NPPCET | 1423 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93749 | |||
...IESLGV | 1792 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5966 | |||
...IESLGV | 1792 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7529 | |||
...IESLGV | 1792 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141954 | |||
...IESLGV | 1792 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142103 | |||
...VTHYFL | 1829 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5969 | |||
...VTHYFL | 1829 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142014 | |||
...VTHYFL | 1829 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142148 | |||
...KADGQ | 2035 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...KADGQ | 2035 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt72400 | |||
...KADGQ | 2035 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt72402 |
Cleavages
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|