Q96CX2: BTB/POZ domain-containing protein KCTD12

General Information

Protein names	- BTB/POZ domain-containing protein KCTD12 - Pfetin - Predominantly fetal expressed T1 domain
Gene names	KCTD12
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96CX2

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALADSTRGL PNGGGGGGGS GSSSSSAEPP LFPDIVELNV GGQVYVTRRC TVVSVPDSLL
        70         80         90        100        110        120
WRMFTQQQPQ ELARDSKGRF FLDRDGFLFR YILDYLRDLQ LVLPDYFPER SRLQREAEYF
       130        140        150        160        170        180
ELPELVRRLG APQQPGPGPP PSRRGVHKEG SLGDELLPLG YSEPEQQEGA SAGAPSPTLE
       190        200        210        220        230        240
LASRSPSGGA AGPLLTPSQS LDGSRRSGYI TIGYRGSYTI GRDAQADAKF RRVARITVCG
       250        260        270        280        290        300
KTSLAKEVFG DTLNESRDPD RPPERYTSRY YLKFNFLEQA FDKLSESGFH MVACSSTGTC
       310        320
AFASSTDQSE DKIWTSYTEY VFCRE

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96CX2-2-unknown	MALADS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96CX2-2-Acetylation	ALADST...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96CX2-2-Acetylation	ALADST...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q96CX2-66-unknown	QQQPQE...	66		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8012
Q96CX2-196-unknown	TPSQSL...	196		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6661

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...WRMFTQ	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8012
...AGPLLT	195	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6661
...VFCRE	325	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	65	MFTQ.\|.QQQP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	195	PLLT.\|.TPSQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)