Q8TEA8: D-aminoacyl-tRNA deacylase 1 {ECO:0000250|UniProtKB:Q8IIS0}

General Information

Protein names	- D-aminoacyl-tRNA deacylase 1 {ECO:0000250\|UniProtKB:Q8IIS0} - DTD - 3.1.1.96 {ECO:0000250\|UniProtKB:Q8IIS0} - DNA-unwinding element-binding protein B {ECO:0000303\|PubMed:15653697} - DUE-B {ECO:0000303\|PubMed:15653697} - Gly-tRNA(Ala) deacylase {ECO:0000250\|UniProtKB:Q8IIS0} - 3.1.1.- {ECO:0000250\|UniProtKB:Q8IIS0} - Histidyl-tRNA synthase-related
Gene names	DTD1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8TEA8

2 N-termini

2 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MKAVVQRVTR ASVTVGGEQI SAIGRGICVL LGISLEDTQK ELEHMVRKIL NLRVFEDESG
        70         80         90        100        110        120
KHWSKSVMDK QYEILCVSQF TLQCVLKGNK PDFHLAMPTE QAEGFYNSFL EQLRKTYRPE
       130        140        150        160        170        180
LIKDGKFGAY MQVHIQNDGP VTIELESPAP GTATSDPKQL SKLEKQQQRK EKTRAKGPSE
       190        200
SSKERNTPRK EDRSASSGAE GDVSSEREP

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8TEA8-1-unknown	MKAVVQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8TEA8-1-unknown	MKAVVQ...	1		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q8TEA8-1-unknown	MKAVVQ...	1		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q8TEA8-147-unknown	SPAPGT...	147	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7961
Q8TEA8-147-unknown	SPAPGT...	147	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6597

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TIELES	146	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7961
...TIELES	146	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6597
...SEREP	209	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	146	ELES.\|.SPAP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	146	ELES.\|.SPAP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)