Q9GZV4: Eukaryotic translation initiation factor 5A-2

General Information

Protein names	- Eukaryotic translation initiation factor 5A-2 - eIF-5A-2 - eIF-5A2 - Eukaryotic initiation factor 5A isoform 2
Gene names	EIF5A2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9GZV4

5 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADEIDFTTG DAGASSTYPM QCSALRKNGF VVLKGRPCKI VEMSTSKTGK HGHAKVHLVG
        70         80         90        100        110        120
IDIFTGKKYE DICPSTHNMD VPNIKRNDYQ LICIQDGYLS LLTETGEVRE DLKLPEGELG
       130        140        150
KEIEGKYNAG EDVQVSVMCA MSEEYAVAIK PCK

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9GZV4-2-unknown	MADEID...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9GZV4-2-Acetylation	ADEIDF...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9GZV4-2-Acetylation	ADEIDF...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9GZV4-2-Acetylation	ADEIDF...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9GZV4-20-unknown	MQCSAL...	20		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000417133
Q9GZV4-71-unknown	DICPST...	71		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6768
Q9GZV4-71-unknown	DICPST...	71		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8081
Q9GZV4-76-unknown	THNMDV...	76		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8082

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GKKYED	70	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6768
...GKKYED	70	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8081
...DICPST	75	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8082
...GEDVQV	134	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417133
...IKPCK	153	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	70	KYED.\|.DICP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	70	KYED.\|.DICP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	75	CPST.\|.THNM	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)