TopFIND 4.0

P61457: Pterin-4-alpha-carbinolamine dehydratase

General Information

Protein names	- Pterin-4-alpha-carbinolamine dehydratase - PHS - 4.2.1.96 - 4-alpha-hydroxy-tetrahydropterin dehydratase - Dimerization cofactor of hepatocyte nuclear factor 1-alpha - DCoH - Dimerization cofactor of HNF1 - Phenylalanine hydroxylase-stimulating protein - Pterin carbinolamine dehydratase - PCD
Gene names	PCBD1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P61457

3

N-termini

3

C-termini

1

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MAGKAHRLSA EERDQLLPNL RAVGWNELEG RDAIFKQFHF KDFNRAFGFM TRVALQAEKL
70 80 90 100
DHHPEWFNVY NKVHITLSTH ECAGLSERDI NLASFIEQVA VSMT

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P61457-2-unknown	MAGKAH...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P61457-2-Acetylation	AGKAHR...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P61457-78-unknown	STHECA...	78		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7617

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...VHITLS	77	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7617
	...AVSMT	104	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...AVSMT	104		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
	...AVSMT	104		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
	...AVSMT	104		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
	...AVSMT	104		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	77	ITLS.\|.STHE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)