Q13347: Eukaryotic translation initiation factor 3 subunit I {ECO:0000255|HAMAP-Rule:MF_03008}
General Information
Protein names | - Eukaryotic translation initiation factor 3 subunit I {ECO:0000255|HAMAP-Rule:MF_03008} - eIF3i {ECO:0000255|HAMAP-Rule:MF_03008} - Eukaryotic translation initiation factor 3 subunit 2 {ECO:0000255|HAMAP-Rule:MF_03008} - TGF-beta receptor-interacting protein 1 - TRIP-1 - eIF-3-beta {ECO:0000255|HAMAP-Rule:MF_03008} - eIF3 p36 {ECO:0000255|HAMAP-Rule:MF_03008} |
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Gene names | EIF3I |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q13347 |
11
N-termini
5
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MKPILLQGHE RSITQIKYNR EGDLLFTVAK DPIVNVWYSV NGERLGTYMG HTGAVWCVDA
70 80 90 100 110 120
DWDTKHVLTG SADNSCRLWD CETGKQLALL KTNSAVRTCG FDFGGNIIMF STDKQMGYQC
130 140 150 160 170 180
FVSFFDLRDP SQIDNNEPYM KIPCNDSKIT SAVWGPLGEC IIAGHESGEL NQYSAKSGEV
190 200 210 220 230 240
LVNVKEHSRQ INDIQLSRDM TMFVTASKDN TAKLFDSTTL EHQKTFRTER PVNSAALSPN
250 260 270 280 290 300
YDHVVLGGGQ EAMDVTTTST RIGKFEARFF HLAFEEEFGR VKGHFGPINS VAFHPDGKSY
310 320
SSGGEDGYVR IHYFDPQYFE FEFEA
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
11 N-termini - 5 C-termini - 3 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q13347-1- | MKPILL... | 1 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q13347-1- | MKPILL... | 1 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q13347-1- | MKPILL... | 1 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q13347-1- | MKPILL... | 1 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
Q13347-1- | MKPILL... | 1 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q13347-1- | MKPILL... | 1 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q13347-1-unknown | MKPILL... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q13347-174-unknown | SAKSGE... | 174 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19424 | |||
Q13347-216-unknown | DSTTLE... | 216 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19425 | |||
Q13347-217-unknown | STTLEH... | 217 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7770 | |||
Q13347-234- | SAALSP... | 234 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q13347-234- | SAALSP... | 234 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q13347-236- | ALSPNY... | 236 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q13347-236- | ALSPNY... | 236 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q13347-247- | GGGQEA... | 247 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q13347-248- | GGQEAM... | 248 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q13347-290- | SVAFHP... | 290 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q13347-290- | SVAFHP... | 290 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
Q13347-290- | SVAFHP... | 290 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q13347-290- | SVAFHP... | 290 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q13347-299- | SYSSGG... | 299 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...FVSFFD | 125 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000347194 | |||
...ELNQYS | 173 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19424 | |||
...TAKLFD | 215 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19425 | |||
...AKLFDS | 216 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7770 | |||
...FEFEA | 325 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
MEP1B_HUMAN | 173 | NQYS.|.SAKS | inferred from experiment | unknown | MEROPS | Overall CM | Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) | 21693781, |
MEP1B_HUMAN | 215 | KLFD.|.DSTT | inferred from experiment | unknown | MEROPS | Overall CM | Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) | 21693781, |
CATS_HUMAN | 216 | LFDS.|.STTL | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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