TopFIND 4.0

Q9Y333: U6 snRNA-associated Sm-like protein LSm2

General Information

Protein names	- U6 snRNA-associated Sm-like protein LSm2 - Protein G7b - Small nuclear ribonuclear protein D homolog - snRNP core Sm-like protein Sm-x5
Gene names	LSM2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y333

4

N-termini

3

C-termini

1

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MLFYSFFKSL VGKDVVVELK NDLSICGTLH SVDQYLNIKL TDISVTDPEK YPHMLSVKNC
70 80 90
FIRGSVVRYV QLPADEVDTQ LLQDAARKEA LQQKQ

Isoforms

Sequence View

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Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y333-1-unknown	MLFYSF...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y333-1-unmodified	MLFYSF...	1			other		CNRS/ISV	Large_scale_NTA_Human
Q9Y333-1-	MLFYSF...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9Y333-1-	MLFYSF...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9Y333-1-	MLFYSF...	1			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9Y333-31-unknown	SVDQYL...	31		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8156

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...CGTLHS	30	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8156
	...LQQKQ	95		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
	...LQQKQ	95	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...LQQKQ	95		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
	...LQQKQ	95		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	30	TLHS.\|.SVDQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)