Q7Z4W1: L-xylulose reductase

General Information

Protein names	- L-xylulose reductase - XR - 1.1.1.10 - Carbonyl reductase II - Dicarbonyl/L-xylulose reductase - Kidney dicarbonyl reductase - kiDCR - Short chain dehydrogenase/reductase family 20C member 1 - Sperm surface protein P34H
Gene names	DCXR
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7Z4W1

3 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MELFLAGRRV LVTGAGKGIG RGTVQALHAT GARVVAVSRT QADLDSLVRE CPGIEPVCVD
        70         80         90        100        110        120
LGDWEATERA LGSVGPVDLL VNNAAVALLQ PFLEVTKEAF DRSFEVNLRA VIQVSQIVAR
       130        140        150        160        170        180
GLIARGVPGA IVNVSSQCSQ RAVTNHSVYC STKGALDMLT KVMALELGPH KIRVNAVNPT
       190        200        210        220        230        240
VVMTSMGQAT WSDPHKAKTM LNRIPLGKFA EVEHVVNAIL FLLSDRSGMT TGSTLPVEGG

FWAC

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q7Z4W1-1-Acetylation	MELFLA...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7Z4W1-1-Acetylation	MELFLA...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q7Z4W1-1-Acetylation	MELFLA...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q7Z4W1-1-Acetylation	MELFLA...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q7Z4W1-1-Acetylation	MELFLA...	1	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q7Z4W1-57-unknown	VCVDLG...	57		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000463354
Q7Z4W1-188-unknown	QATWSD...	188		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7929

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ALELGP	168	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462226
...IRVNAV	176	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462725
...MTSMGQ	187	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7929
...FLLSDR	225	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462272
...GFWAC	244	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	187	SMGQ.\|.QATW	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)