TopFIND 4.0

P53803: DNA-directed RNA polymerases I, II, and III subunit RPABC4

General Information

Protein names	- DNA-directed RNA polymerases I, II, and III subunit RPABC4 - RNA polymerases I, II, and III subunit ABC4 - ABC10-alpha - DNA-directed RNA polymerase II subunit K - RNA polymerase II 7.0 kDa subunit - RPB7.0 - RPB10alpha
Gene names	POLR2K
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P53803

4

N-termini

3

C-termini

2

Cleavages

0

Substrates

Sequence

10 20 30 40 50
MDTQKDVQPP KQQPMIYICG ECHTENEIKS RDPIRCRECG YRIMYKKRTK RLVVFDAR

Isoforms

Sequence View

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P53803-1-unknown	MDTQKD...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P53803-9-unknown	PPKQQP...	9		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P53803-20-unknown	GECHTE...	20		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6023
P53803-20-unknown	GECHTE...	20		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P53803-20-unknown	GECHTE...	20		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P53803-21-unknown	ECHTEN...	21		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7566

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...MIYICG	19	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6023
	...IYICGE	20	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7566
	...VFDAR	58	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	19	YICG.\|.GECH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	20	ICGE.\|.ECHT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)