P61981: 14-3-3 protein gamma

General Information

Protein names	- 14-3-3 protein gamma - Protein kinase C inhibitor protein 1 - KCIP-1 - 14-3-3 protein gamma, N-terminally processed
Gene names	YWHAG
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P61981

9 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVDREQLVQK ARLAEQAERY DDMAAAMKNV TELNEPLSNE ERNLLSVAYK NVVGARRSSW
        70         80         90        100        110        120
RVISSIEQKT SADGNEKKIE MVRAYREKIE KELEAVCQDV LSLLDNYLIK NCSETQYESK
       130        140        150        160        170        180
VFYLKMKGDY YRYLAEVATG EKRATVVESS EKAYSEAHEI SKEHMQPTHP IRLGLALNYS
       190        200        210        220        230        240
VFYYEIQNAP EQACHLAKTA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDD

DGGEGNN

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

9 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P61981-1-Acetylation	MVDREQ...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P61981-1-unknown	MVDREQ...	1			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P61981-1-unknown	MVDREQ...	1			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P61981-1-	MVDREQ...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P61981-1-	MVDREQ...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P61981-2-Acetylation	VDREQL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P61981-2-Acetylation	VDREQL...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P61981-29-	NVTELN...	29			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P61981-29-	NVTELN...	29			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P61981-29-	NVTELN...	29			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P61981-29-	NVTELN...	29			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P61981-29-	NVTELN...	29			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P61981-62-	VISSIE...	62			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P61981-153-	AYSEAH...	153			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P61981-156-unknown	EAHEIS...	156		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6106
P61981-188-unknown	NAPEQA...	188		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7631

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...EKAYSE	155	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6106
...YYEIQN	187	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7631
...GEGNN	247	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...GEGNN	247		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...GEGNN	247		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	155	AYSE.\|.EAHE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	187	EIQN.\|.NAPE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)