P52209: 6-phosphogluconate dehydrogenase, decarboxylating

General Information

Protein names	- 6-phosphogluconate dehydrogenase, decarboxylating - 1.1.1.44
Gene names	PGD
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P52209

6 N-termini

9 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAQADIALIG LAVMGQNLIL NMNDHGFVVC AFNRTVSKVD DFLANEAKGT KVVGAQSLKE
        70         80         90        100        110        120
MVSKLKKPRR IILLVKAGQA VDDFIEKLVP LLDTGDIIID GGNSEYRDTT RRCRDLKAKG
       130        140        150        160        170        180
ILFVGSGVSG GEEGARYGPS LMPGGNKEAW PHIKTIFQGI AAKVGTGEPC CDWVGDEGAG
       190        200        210        220        230        240
HFVKMVHNGI EYGDMQLICE AYHLMKDVLG MAQDEMAQAF EDWNKTELDS FLIEITANIL
       250        260        270        280        290        300
KFQDTDGKHL LPKIRDSAGQ KGTGKWTAIS ALEYGVPVTL IGEAVFARCL SSLKDERIQA
       310        320        330        340        350        360
SKKLKGPQKF QFDGDKKSFL EDIRKALYAS KIISYAQGFM LLRQAATEFG WTLNYGGIAL
       370        380        390        400        410        420
MWRGGCIIRS VFLGKIKDAF DRNPELQNLL LDDFFKSAVE NCQDSWRRAV STGVQAGIPM
       430        440        450        460        470        480
PCFTTALSFY DGYRHEMLPA SLIQAQRDYF GAHTYELLAK PGQFIHTNWT GHGGTVSSSS

YNA

Isoforms

- Isoform 2 of 6-phosphogluconate dehydrogenase, decarboxylating

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 9 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P52209-2-unknown	AQADIA...	2	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P52209-2-unknown	AQADIA...	2	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P52209-14-unknown	MGQNLI...	14	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466358
P52209-14-unknown	MGQNLI...	14	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466574
P52209-14-unknown	MGQNLI...	14	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000437822
P52209-124-unknown	VGSGVS...	124	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3826
P52209-126-unknown	SGVSGG...	126	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5981
P52209-126-unknown	SGVSGG...	126	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7537
P52209-176-unknown	DEGAGH...	176	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7538
P52209-311-unknown	QFDGDK...	311	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14194

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KGILFV	123	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3826
...ILFVGS	125	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5981
...ILFVGS	125	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7537
...PCCDWV	173	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466574
...CDWVGD	175	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7538
...DEMAQA	218	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466358
...PVTLIG	281	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000467362
...GPQKFQ	310	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14194
...GCIIRS	369	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466156
...SSYNA	483	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	123	ILFV.\|.VGSG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	125	FVGS.\|.SGVS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	125	FVGS.\|.SGVS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	175	WVGD.\|.DEGA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAM_HUMAN	310	QKFQ.\|.QFDG	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)