Q92804: TATA-binding protein-associated factor 2N

General Information

Protein names	- TATA-binding protein-associated factor 2N - 68 kDa TATA-binding protein-associated factor - TAF(II)68 - TAFII68 - RNA-binding protein 56
Gene names	TAF15
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q92804

21 N-termini

5 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSDSGSYGQS GGEQQSYSTY GNPGSQGYGQ ASQSYSGYGQ TTDSSYGQNY SGYSSYGQSQ
        70         80         90        100        110        120
SGYSQSYGGY ENQKQSSYSQ QPYNNQGQQQ NMESSGSQGG RAPSYDQPDY GQQDSYDQQS
       130        140        150        160        170        180
GYDQHQGSYD EQSNYDQQHD SYSQNQQSYH SQRENYSHHT QDDRRDVSRY GEDNRGYGGS
       190        200        210        220        230        240
QGGGRGRGGY DKDGRGPMTG SSGGDRGGFK NFGGHRDYGP RTDADSESDN SDNNTIFVQG
       250        260        270        280        290        300
LGEGVSTDQV GEFFKQIGII KTNKKTGKPM INLYTDKDTG KPKGEATVSF DDPPSAKAAI
       310        320        330        340        350        360
DWFDGKEFHG NIIKVSFATR RPEFMRGGGS GGGRRGRGGY RGRGGFQGRG GDPKSGDWVC
       370        380        390        400        410        420
PNPSCGNMNF ARRNSCNQCN EPRPEDSRPS GGDFRGRGYG GERGYRGRGG RGGDRGGYGG
       430        440        450        460        470        480
DRSGGGYGGD RSSGGGYSGD RSGGGYGGDR SGGGYGGDRG GGYGGDRGGG YGGDRGGGYG
       490        500        510        520        530        540
GDRGGYGGDR GGGYGGDRGG YGGDRGGYGG DRGGYGGDRG GYGGDRSRGG YGGDRGGGSG
       550        560        570        580        590
YGGDRSGGYG GDRSGGGYGG DRGGGYGGDR GGYGGKMGGR NDYRNDQRNR PY

Isoforms

- Isoform Short of TATA-binding protein-associated factor 2N

Sequence View

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Protein Neighborhood

Domains & Features

21 N-termini - 5 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q92804-1-unknown	MSDSGS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q92804-1-unknown	MSDSGS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87171
Q92804-57-	GQSQSG...	57		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q92804-60-	QSGYSQ...	60		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q92804-62-	GYSQSY...	62		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q92804-64-	SQSYGG...	64		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q92804-64-unknown	SQSYGG...	64	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173316
Q92804-66-	SYGGYE...	66		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q92804-66-unknown	SYGGYE...	66	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4174
Q92804-66-unknown	SYGGYE...	66	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173318
Q92804-77-	SYSQQP...	77		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q92804-77-unknown	SYSQQP...	77	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170799
Q92804-110-unknown	YGQQDS...	110	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2966
Q92804-110-unknown	YGQQDS...	110	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2278
Q92804-110-unknown	YGQQDS...	110	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142765
Q92804-115-unknown	SYDQQS...	115	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13010
Q92804-115-unknown	SYDQQS...	115	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143086
Q92804-141-	SYSQNQ...	141		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q92804-141-	SYSQNQ...	141		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q92804-141-	SYSQNQ...	141		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q92804-141-	SYSQNQ...	141		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q92804-141-	SYSQNQ...	141		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q92804-141-unknown	SYSQNQ...	141		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q92804-141-unknown	SYSQNQ...	141	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161976
Q92804-211-	NFGGHR...	211		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q92804-211-unknown	NFGGHR...	211	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178520
Q92804-378-unknown	QCNEPR...	378	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7988
Q92804-378-unknown	QCNEPR...	378	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151501
Q92804-423-	SGGGYG...	423		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q92804-423-unknown	SGGGYG...	423		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q92804-423-unknown	SGGGYG...	423	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161972
Q92804-546-	SGGYGG...	546		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q92804-546-unknown	SGGYGG...	546		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q92804-546-unknown	SGGYGG...	546	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161974

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SGYSQS	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4174
...YDQPDY	109	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2966
...YDQPDY	109	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2278
...YDQPDY	109	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125969
...YGQQDS	114	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13010
...YGQQDS	114	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126304
...RNSCNQ	377	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7988
...RNSCNQ	377	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134906
...RNRPY	592	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...RNRPY	592	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82789

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	65	YSQS.\|.SYGG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CASP7_HUMAN	109	QPDY.\|.YGQQ	inferred from experiment	unknown	MEROPS	Li J	Alves J et al.:TAF15 and the leukemia-associat... (C14.003)	19426707,
CASP3_HUMAN	109	QPDY.\|.YGQQ	inferred from experiment	unknown	MEROPS	Li J	Alves J et al.:TAF15 and the leukemia-associat... (C14.003)	19426707,
GRAB_HUMAN	114	QQDS.\|.SYDQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
CATS_HUMAN	377	SCNQ.\|.QCNE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)