Q16576: Histone-binding protein RBBP7

General Information

Protein names	- Histone-binding protein RBBP7 - Histone acetyltransferase type B subunit 2 - Nucleosome-remodeling factor subunit RBAP46 - Retinoblastoma-binding protein 7 - RBBP-7 - Retinoblastoma-binding protein p46
Gene names	RBBP7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q16576

12 N-termini

8 C-termini

9 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASKEMFEDT VEERVINEEY KIWKKNTPFL YDLVMTHALQ WPSLTVQWLP EVTKPEGKDY
        70         80         90        100        110        120
ALHWLVLGTH TSDEQNHLVV ARVHIPNDDA QFDASHCDSD KGEFGGFGSV TGKIECEIKI
       130        140        150        160        170        180
NHEGEVNRAR YMPQNPHIIA TKTPSSDVLV FDYTKHPAKP DPSGECNPDL RLRGHQKEGY
       190        200        210        220        230        240
GLSWNSNLSG HLLSASDDHT VCLWDINAGP KEGKIVDAKA IFTGHSAVVE DVAWHLLHES
       250        260        270        280        290        300
LFGSVADDQK LMIWDTRSNT TSKPSHLVDA HTAEVNCLSF NPYSEFILAT GSADKTVALW
       310        320        330        340        350        360
DLRNLKLKLH TFESHKDEIF QVHWSPHNET ILASSGTDRR LNVWDLSKIG EEQSAEDAED
       370        380        390        400        410        420
GPPELLFIHG GHTAKISDFS WNPNEPWVIC SVSEDNIMQI WQMAENIYND EESDVTTSEL

EGQGS

Isoforms

- Isoform 2 of Histone-binding protein RBBP7

Sequence View

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Protein Neighborhood

Domains & Features

12 N-termini - 8 C-termini - 9 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q16576-2-unknown	MASKEM...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q16576-2-Acetylation	ASKEMF...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q16576-2-Acetylation	ASKEMF...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q16576-2-Acetylation	ASKEMF...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q16576-2-Acetylation	ASKEMF...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q16576-6-	MFEDTV...	6			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q16576-46-unknown	VQWLPE...	46		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4118
Q16576-46-unknown	VQWLPE...	46		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt141801
Q16576-68-unknown	GTHTSD...	68		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4120
Q16576-68-unknown	GTHTSD...	68		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6490
Q16576-68-unknown	GTHTSD...	68		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7879
Q16576-68-unknown	GTHTSD...	68		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143041
Q16576-69-unknown	THTSDE...	69		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7881
Q16576-69-unknown	THTSDE...	69		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143137
Q16576-94-unknown	ASHCDS...	94		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7883
Q16576-94-unknown	ASHCDS...	94		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144225
Q16576-99-	SDKGEF...	99			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q16576-99-	SDKGEF...	99			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q16576-99-	SDKGEF...	99			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q16576-99-	SDKGEF...	99			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q16576-99-unknown	SDKGEF...	99			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q16576-99-unknown	SDKGEF...	99		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161968
Q16576-135-unknown	NPHIIA...	135		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6492
Q16576-135-unknown	NPHIIA...	135		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145856
Q16576-314-unknown	SHKDEI...	314		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6494
Q16576-314-unknown	SHKDEI...	314		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151107
Q16576-361-unknown	GPPELL...	361		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19590
Q16576-361-unknown	GPPELL...	361		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152069

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...WPSLTV	45	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4118
...WPSLTV	45	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124982
...HWLVLG	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4120
...HWLVLG	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6490
...HWLVLG	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7879
...HWLVLG	67	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126260
...WLVLGT	68	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7881
...WLVLGT	68	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126359
...DAQFDA	93	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7883
...DAQFDA	93	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127478
...RYMPQN	134	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6492
...RYMPQN	134	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129154
...LHTFES	313	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6494
...LHTFES	313	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134509
...EDAEDG	360	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19590
...EDAEDG	360	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135478
...EGQGS	425	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EGQGS	425	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82665

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	45	SLTV.\|.VQWL	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	67	LVLG.\|.GTHT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	67	LVLG.\|.GTHT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	67	LVLG.\|.GTHT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	68	VLGT.\|.THTS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	93	QFDA.\|.ASHC	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	134	MPQN.\|.NPHI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	313	TFES.\|.SHKD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1B_HUMAN	360	AEDG.\|.GPPE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)