Q13011: Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

General Information

Protein names	- Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial - 5.3.3.-
Gene names	ECH1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13011

8 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAGIVASRR LRDLLTRRLT GSNYPGLSIS LRLTGSSAQE EASGVALGEA PDHSYESLRV
        70         80         90        100        110        120
TSAQKHVLHV QLNRPNKRNA MNKVFWREMV ECFNKISRDA DCRAVVISGA GKMFTAGIDL
       130        140        150        160        170        180
MDMASDILQP KGDDVARISW YLRDIITRYQ ETFNVIERCP KPVIAAVHGG CIGGGVDLVT
       190        200        210        220        230        240
ACDIRYCAQD AFFQVKEVDV GLAADVGTLQ RLPKVIGNQS LVNELAFTAR KMMADEALGS
       250        260        270        280        290        300
GLVSRVFPDK EVMLDAALAL AAEISSKSPV AVQSTKVNLL YSRDHSVAES LNYVASWNMS
       310        320
MLQTQDLVKS VQATTENKEL KTVTFSKL

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

8 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13011-33-	LTGSSA...	33		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q13011-33-	LTGSSA...	33		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q13011-33-	LTGSSA...	33		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q13011-34-unknown	TGSSAQ...	34	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13011-34-	TGSSAQ...	34		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q13011-34-	TGSSAQ...	34		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q13011-34-	TGSSAQ...	34		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q13011-35-	GSSAQE...	35		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q13011-35-	GSSAQE...	35		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q13011-35-	GSSAQE...	35		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q13011-35-	GSSAQE...	35		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q13011-35-	GSSAQE...	35		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q13011-35-	GSSAQE...	35		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q13011-36-	SSAQEE...	36		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q13011-36-	SSAQEE...	36		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q13011-36-	SSAQEE...	36		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q13011-36-	SSAQEE...	36		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q13011-42-	ASGVAL...	42		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q13011-42-	ASGVAL...	42		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q13011-42-	ASGVAL...	42		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q13011-42-	ASGVAL...	42		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q13011-49-unknown	EAPDHS...	49	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7756
Q13011-81-unknown	MNKVFW...	81	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000469354

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GSSAQE	39	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000470519
...GVALGE	48	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7756
...KMFTAG	116	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000469354
...KMFTAG	116	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000471738
...SLNYVA	294	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472322
...TFSKL	328	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	48	ALGE.\|.EAPD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)