Q04323: UBX domain-containing protein 1

General Information

Protein names	- UBX domain-containing protein 1 - SAPK substrate protein 1 - UBA/UBX 33.3 kDa protein
Gene names	UBXN1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q04323

7 N-termini

2 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAELTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PLETPLGHIL
        70         80         90        100        110        120
GREPTSSEQG GLEGSGSAAG EGKPALSEEE RQEQTKRMLE LVAQKQRERE EREEREALER
       130        140        150        160        170        180
ERQRRRQGQE LSAARQRLQE DEMRRAAEER RREKAEELAA RQRVREKIER DKAERAKKYG
       190        200        210        220        230        240
GSVGSQPPPV APEPGPVPSS PSQEPPTKRE YDQCRIQVRL PDGTSLTQTF RAREQLAAVR
       250        260        270        280        290
LYVELHRGEE LGGGQDPVQL LSGFPRRAFS EADMERPLQE LGLVPSAVLI VAKKCPS

Isoforms

- Isoform 2 of UBX domain-containing protein 1

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q04323-2-unknown	MAELTA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q04323-1-unknown	MAELTA...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93782
Q04323-2-Acetylation	AELTAL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q04323-2-Acetylation	AELTAL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q04323-2-Acetylation	AELTAL...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111089
Q04323-74-unknown	GSGSAA...	74		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7726
Q04323-74-unknown	GSGSAA...	74		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6223
Q04323-74-unknown	GSGSAA...	74		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt140874
Q04323-153-Pyrrolidone carboxylic acid (Glu)	EKAEEL...	153	pyrrolidone carboxylic acid-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q04323-153-Pyrrolidone carboxylic acid (Glu)	EKAEEL...	153	pyrrolidone carboxylic acid-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183006
Q04323-185-unknown	SQPPPV...	185		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168054
Q04323-185-	SQPPPV...	185			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q04323-185-	SQPPPV...	185			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q04323-185-	SQPPPV...	185			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QGGLEG	73	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7726
...QGGLEG	73	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6223
...QGGLEG	73	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124014
...KKCPS	297	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	73	GLEG.\|.GSGS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	73	GLEG.\|.GSGS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)