TopFIND 4.0

P62861: 40S ribosomal protein S30

General Information

Protein names	- 40S ribosomal protein S30 - Small ribosomal subunit protein eS30 {ECO:0000303\|PubMed:24524803}
Gene names	FAU
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P62861

7

N-termini

6

C-termini

4

Cleavages

0

Substrates

Sequence

10 20 30 40 50
KVHGSLARAG KVRGQTPKVA KQEKKKKKTG RAKRRMQYNR RFVNVVPTFG KKKGPNANS

Isoforms

Sequence View

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Evidence Codes:

Methodology:

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Protease Assignment Confidence:

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Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 6 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P62861-1-unknown	KVHGSL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62861-1-unknown	KVHGSL...	1			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P62861-1-unknown	KVHGSL...	1			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P62861-1-	KVHGSL...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P62861-1-	KVHGSL...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P62861-1-	KVHGSL...	1			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P62861-1-	KVHGSL...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P62861-1-	KVHGSL...	1			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P62861-1-	KVHGSL...	1			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P62861-14-unknown	GQTPKV...	14		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6134
P62861-26-unknown	KKKTGR...	26		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14275
P62861-43-	VNVVPT...	43			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P62861-43-unknown	VNVVPT...	43			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P62861-45-unknown	VVPTFG...	45		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7655
P62861-45-unknown	VVPTFG...	45		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6135

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...AGKVRG	13	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6134
	...KQEKKK	25	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14275
	...GRAKRR	34	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000433139
	...RRFVNV	44	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7655
	...RRFVNV	44	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6135
	...PNANS	59		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
	...PNANS	59		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
	...PNANS	59	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...PNANS	59		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
	...PNANS	59		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	13	KVRG.\|.GQTP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAM_HUMAN	25	EKKK.\|.KKKT	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CATS_HUMAN	44	FVNV.\|.VVPT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	44	FVNV.\|.VVPT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)