P49593: Protein phosphatase 1F

General Information

Protein names	- Protein phosphatase 1F - 3.1.3.16 - Ca(2+)/calmodulin-dependent protein kinase phosphatase - CaM-kinase phosphatase - CaMKPase - Partner of PIX 2 - Protein fem-2 homolog - hFem-2
Gene names	PPM1F
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P49593

4 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSSGAPQKSS PMASGAEETP GFLDTLLQDF PALLNPEDPL PWKAPGTVLS QEEVEGELAE
        70         80         90        100        110        120
LAMGFLGSRK APPPLAAALA HEAVSQLLQT DLSEFRKLPR EEEEEEEDDD EEEKAPVTLL
       130        140        150        160        170        180
DAQSLAQSFF NRLWEVAGQW QKQVPLAARA SQRQWLVSIH AIRNTRRKME DRHVSLPSFN
       190        200        210        220        230        240
QLFGLSDPVN RAYFAVFDGH GGVDAARYAA VHVHTNAARQ PELPTDPEGA LREAFRRTDQ
       250        260        270        280        290        300
MFLRKAKRER LQSGTTGVCA LIAGATLHVA WLGDSQVILV QQGQVVKLME PHRPERQDEK
       310        320        330        340        350        360
ARIEALGGFV SHMDCWRVNG TLAVSRAIGD VFQKPYVSGE ADAASRALTG SEDYLLLACD
       370        380        390        400        410        420
GFFDVVPHQE VVGLVQSHLT RQQGSGLRVA EELVAAARER GSHDNITVMV VFLRDPQELL
       430        440        450
EGGNQGEGDP QAEGRRQDLP SSLPEPETQA PPRS

Isoforms

- Isoform 2 of Protein phosphatase 1F

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
P49593-1-unknown	MSSGAP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P49593-2-acetylation	SSGAPQ...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P49593-169-unknown	MEDRHV...	169		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000384930
P49593-169-unknown	MEDRHV...	169		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000392372
P49593-422-unknown	GGNQGE...	422		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7517

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LFGLSD	186	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000388350
...SGTTGV	257	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000392372
...QELLEG	421	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7517
...APPRS	454	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	421	LLEG.\|.GGNQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)