O00764: Pyridoxal kinase

General Information

Protein names	- Pyridoxal kinase - 2.7.1.35 - Pyridoxine kinase
Gene names	PDXK
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O00764

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Pyridoxal kinase - Isoform 3 of Pyridoxal kinase

Sequence View

        10         20         30         40         50         60
MEEECRVLSI QSHVIRGYVG NRAATFPLQV LGFEIDAVNS VQFSNHTGYA HWKGQVLNSD
        70         80         90        100        110        120
ELQELYEGLR LNNMNKYDYV LTGYTRDKSF LAMVVDIVQE LKQQNPRLVY VCDPVLGDKW
       130        140        150        160        170        180
DGEGSMYVPE DLLPVYKEKV VPLADIITPN QFEAELLSGR KIHSQEEALR VMDMLHSMGP
       190        200        210        220        230        240
DTVVITSSDL PSPQGSNYLI VLGSQRRRNP AGSVVMERIR MDIRKVDAVF VGTGDLFAAM
       250        260        270        280        290        300
LLAWTHKHPN NLKVACEKTV STLHHVLQRT IQCAKAQAGE GVRPSPMQLE LRMVQSKRDI
       310
EDPEIVVQAT VL         10         20         30         40         50         60
MEEECRVLSI QSHVIRGYVG NRAATFPLQV LGFEIDAVNS VQFSNHTGYA HWKGQVLNSD
        70         80         90        100        110        120
ELQELYEGLR LNNMNKYDYV LTGYTRDKSF LAMVVDIVQE LKQQNPRLVY VCDPVLGDKW
       130        140        150        160        170        180
DGEGSMYVPE DLLPVYKEKV VPLADIITPN QFEAELLSGR KIHSQEEALR VMDMLHSMGP
       190        200        210        220        230        240
DTVVITSSDL PSPQGSNYLI VLGSQRRRNP AGSVVMERIR MDIRKVDAVF VGTGDLFAAM
       250        260        270        280        290        300
LLAWTHKHPN NLKVACEKTV STLHHVLQRT IQCAKAQAGE GVRPSPMQLE LRMVQSKRDI
       310
EDPEIVVQAT VL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
O00764-1-unknown	MEEECR...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84798
O00764-1-Acetylation	MEEECR...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O00764-1-Acetylation	MEEECR...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt103155
O00764-10-unknown	IQSHVI...	10		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6993
O00764-10-unknown	IQSHVI...	10		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt194866
O00764-74-unknown	MNKYDY...	74		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84799

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...CRVLSI	9	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6993
...QATVL	312	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...QATVL	312	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80417
...QATVL	312	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80416

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	9	VLSI.\|.IQSH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)